Multilevel Dimension-Independent Likelihood-Informed MCMC for Large-Scale Inverse Problems [PDF]
We present a non-trivial integration of dimension-independent likelihood-informed (DILI) MCMC (Cui, Law, Marzouk, 2016) and the multilevel MCMC (Dodwell et al., 2015) to explore the hierarchy of posterior distributions. This integration offers several advantages: First, DILI-MCMC employs an intrinsic likelihood-informed subspace (LIS) (Cui et al., 2014)
arxiv
AN ANALYSIS OF CASES OF DRUG-INDUCED LIVER INJURY REPORTED TO AN ADVERSE DRUG REACTION MONITORING CENTER [PDF]
Objectives: Drug-induced liver injury (DILI) is a frequent cause of liver injury and acute liver failure .We aimed to analyze the cases of DILI reported over a period of 8 years to the adverse drug reaction (ADR) monitoring center (AMC) at our ...
DESAI, CHETNA+4 more
core +1 more source
Drug induced liver injury: risk factors [PDF]
Introduction. Drug induced liver injury (DILI) is a relatively rare hepatic condition as a result of the use of illegal drugs, herbal products, dietary supplements, medications or other xenobiotics.
Guzun, Cristina
core
Progress in the treatment of drug-induced liver injury with natural products
There are numerous prescription drugs and non-prescription drugs that cause drug-induced liver injury (DILI), which is the main cause of liver disease in humans around the globe. Its mechanism becomes clearer as the disease is studied further.
Yuan-kai Sun+7 more
doaj
Venlafaxine induced hepatotoxicity in a carcinoma of breast survivor with co-morbid depression [PDF]
Drug Induced Liver Injury (DILI) is one of the leading causes of liver damage worldwide and raises concerns about its prescription in lieu of the limited drug options available for the depression.
Bhagat, Nisha, Raj, Rajnish
core +2 more sources
Infliximab (IFX)-Biosimilar Induced Drug-Induced Liver Injury (DILI): A Case Report. [PDF]
Zachou M+4 more
europepmc +1 more source
Drug induced liver injury: accuracy of diagnosis in published reports
The diagnosis of drug induced liver injury (DILI) is based primarily on the exclusion of alternative causes. To assess the frequency of alternative causes in initially suspected DILI cases, we searched the Medline database with the following terms: drug ...
Rolf Teschke+4 more
doaj
Drug-Induced Liver Injury: An Institutional Case Series and Review of Literature
Drug-induced liver injury (DILI) is the most common cause of acute liver failure in the USA. DILI can be broadly classified as Intrinsic and Idiosyncratic.
Vijay Gayam MD+8 more
doaj +1 more source
Gene networks-based mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney [PDF]
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.
Wijaya, L.S.
core +1 more source
Drug-Induced Liver Injury during Antidepressant Treatment: Results of AMSP, a Drug Surveillance Program [PDF]
Background: Drug-induced liver injury is a common cause of liver damage and the most frequent reason for withdrawal of a drug in the United States. The symptoms of drug-induced liver damage are extremely diverse, with some patients remaining asymptomatic.
Akimova, Elena+9 more
core +1 more source