Results 151 to 160 of about 20,588 (191)
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Drug-induced liver injury (DILI)
, 2012S. Russmann, G. Kullak-Ublick
semanticscholar +3 more sources
Critical Reviews in Toxicology, 2017
Drug-induced liver injury (DILI) is a major safety issue during drug development, as well as the most common cause for the withdrawal of drugs from the pharmaceutical market. The identification of DILI biomarkers is a labor-intensive area. Conventional biomarkers are not specific and often only appear at significant levels when liver damage is ...
A. M. Araújo +4 more
semanticscholar +5 more sources
Drug-induced liver injury (DILI) is a major safety issue during drug development, as well as the most common cause for the withdrawal of drugs from the pharmaceutical market. The identification of DILI biomarkers is a labor-intensive area. Conventional biomarkers are not specific and often only appear at significant levels when liver damage is ...
A. M. Araújo +4 more
semanticscholar +5 more sources
American Journal of Gastroenterology, 2023
INTRODUCTION: Diagnosis of drug-induced liver injury (DILI) is difficult. We reviewed cases in the DILI Network prospective study that were adjudicated to have liver injury due to other causes to discover pearls for improved diagnostic accuracy.
A Sidney, Barritt +5 more
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INTRODUCTION: Diagnosis of drug-induced liver injury (DILI) is difficult. We reviewed cases in the DILI Network prospective study that were adjudicated to have liver injury due to other causes to discover pearls for improved diagnostic accuracy.
A Sidney, Barritt +5 more
openaire +2 more sources
Chemical Research in Toxicology, 2020
The hepatic risk matrix (HRM) was developed and used to differentiate lead clinical and back-up drug candidates against competitor/marketed drugs within the same pharmaceutical class for their potential to cause human drug-induced liver injury (DILI ...
M. Aleo +10 more
semanticscholar +1 more source
The hepatic risk matrix (HRM) was developed and used to differentiate lead clinical and back-up drug candidates against competitor/marketed drugs within the same pharmaceutical class for their potential to cause human drug-induced liver injury (DILI ...
M. Aleo +10 more
semanticscholar +1 more source
Case of cholestatic drug-induced liver injury (DILI) associated with black cohosh
BMJ Case Reports, 2021Drug-induced liver injury is an uncommon yet fatal cause of liver injury. Black cohosh is a herbal supplement that is derived from Actaea racemosa. It has been used for vasomotor symptoms in postmenopausal women, but it can cause liver injury. A 50-year-old Afro-American woman presented with a 2-month history of malaise, itching and severe jaundice ...
Rachana Marathi, Himmat S. Brar
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, 2020
Drug-induced liver injury (DILI) is a growing challenge because of the ever- increasing number of drugs used in medical care. DILI is rare but can be serious and is largely unpredictable.
semanticscholar +1 more source
Drug-induced liver injury (DILI) is a growing challenge because of the ever- increasing number of drugs used in medical care. DILI is rare but can be serious and is largely unpredictable.
semanticscholar +1 more source
Arzneimittel als Auslöser von Leberschäden [PDF]
MMW - Fortschritte der Medizin, 2019 Medikamenten-induzierte Leberschaden (Drug-induced liver injuries, DILI) fuhren zunachst zu auffalligen Leberparametern. Sie sind zwar selten, in den USA und Europa aber die haufigste Ursache fur das akute Leberversagen. Daher stellen sie eine wichtige Differenzialdiagnose dar. Der Hausarzt muss v. a. bei der Anamnese grundlich vorgehen.
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Steatosis as risk factor for drug-induced liver injury (DILI)
Toxicology Letters, 2021A. Wolf +5 more
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WHY TARGET AYURVEDIC DRUGS FOR DRUG INDUCED LIVER INJURY (DILI)?
Indian drugsDear Reader, Use of herbs as medicines is as old as history of human civilization. Discovery of most of the modern medicines dates back to 19th and 20th century.
semanticscholar +1 more source
DRUG-INDUCED LIVER INJURY-DILI AND HILI IN CLINICAL PRACTICE
Drug-induced liver damage is still a problem for modern medicine. On the one hand, it is related tothe polyprogression found mainly in the elderly and chronically ill, and on the other hand, to thefashion for young people to use dietary supplements and herbs. The course of DILI can range froma mild, asymptomatic, reversible increase in liver parametersRajewski, Paweł +2 more
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