Results 161 to 170 of about 26,250 (194)

MOVING BEYOND BINARY PREDICTIONS OF HUMAN DRUG-INDUCED LIVER INJURY (DILI) TOWARDS CONTRASTING RELATIVE RISK POTENTIAL.

Chemical Research in Toxicology, 2020
The hepatic risk matrix (HRM) was developed and used to differentiate lead clinical and back-up drug candidates against competitor/marketed drugs within the same pharmaceutical class for their potential to cause human drug-induced liver injury (DILI ...
M. Aleo, F. Shah, S. Allen, Hugh A. Barton, Chester Costales, Sarah Lazzaro, Louis Leung, Andrea L. Nilson, R. Obach, A. David Rodrigues, Y. Will   +10 more
semanticscholar   +1 more source

Drug-Induced Liver Injury (DILI): Current status and future directions for drug development and the post-market setting

, 2020
Drug-induced liver injury (DILI) is a growing challenge because of the ever- increasing number of drugs used in medical care. DILI is rare but can be serious and is largely unpredictable.

semanticscholar   +1 more source

Drug-Induced Liver Injury (DILI) With Micafungin: The Importance of Causality Assessment

The Annals of Pharmacotherapy, 2019
Background: Micafungin is increasingly used in the treatment and prevention of candidiasis in hospitalized patients. Limited data are available from which to assess the risk of drug-induced liver injury (DILI) with micafungin.
Caitlin Mullins, Kirthana Beaulac, L. Sylvia   +2 more
semanticscholar   +1 more source

WHY TARGET AYURVEDIC DRUGS FOR DRUG INDUCED LIVER INJURY (DILI)?

Indian drugs
Dear Reader, Use of herbs as medicines is as old as history of human civilization. Discovery of most of the modern medicines dates back to 19th and 20th century.

semanticscholar   +1 more source

Drug-induced liver injury (DILI)

, 2012
S. Russmann, G. Kullak-Ublick
semanticscholar   +1 more source

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

Ca-A Cancer Journal for Clinicians, 2021
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel   +2 more
exaly  

Cancer statistics, 2023

Ca-A Cancer Journal for Clinicians, 2023
Rebecca L Siegel, Kimberly D Miller, Nikita Sandeep Wagle   +2 more
exaly  

Global Epidemiology of Drug-Induced Liver Injury (DILI)

Current Hepatology Reports, 2019
E. Björnsson
semanticscholar   +2 more sources

Onconephrology: The intersections between the kidney and cancer

Ca-A Cancer Journal for Clinicians, 2021
Kenar D Jhaveri, Mark A Perazella
exaly  

In vitro to in vivo extrapolation and species response comparisons for drug-induced liver injury (DILI) using DILIsym™: a mechanistic, mathematical model of DILI

Journal of Pharmacokinetics and Pharmacodynamics, 2012
B. Howell, Yuching Yang, Rukmini Kumar, J. Woodhead, A. Harrill, H. Clewell, M. Andersen, S. Siler, P. Watkins   +8 more
semanticscholar   +1 more source