Results 61 to 70 of about 11,641 (246)

Acute Liver Failure Due to Etodolac, a Selective Cycloxygenase- 2 (COX -2) Inhibitor Non-Steroidal Anti-Inflammatory Drug Established by RUCAM-Based Causality Assessment

Annals of Hepatology, 2017
Drug induced liver injury is a common cause of acute liver failure (ALF). While most of these cases are due to dose dependent hepa-totoxicity with acetaminophen, idiosyncratic drug-induced liver injury (DILI) is responsible for about 15% cases of ALF ...
Sunil Taneja, Pramod Kumar, Sahaj Rathi, Ajay Duseja, Virendra Singh, Radha Krishan Dhiman, Yogesh Kumar Chawla   +6 more
doaj   +1 more source

Drug‐Induced Liver Injury in GI Practice

Hepatology Communications, 2020
Although drug‐induced liver injury (DILI) is a rare clinical event, it carries significant morbidity and mortality, leaving it as the leading cause of acute liver failure in the United States.
Naemat Sandhu, Victor Navarro
doaj   +1 more source

Death and Liver Transplantation within Two Years of Onset of Drug-Induced Liver Injury [PDF]

, 2017
Drug-induced liver injury (DILI) is an important cause of death and indication for liver transplantation (fatality). The role of DILI in these fatalities ispoorly characterized particularly when fatalities occur > 26 weeks after DILI onset.
Anania, Andrade, Bjornsson, Chalasani, Fontana, Fontana, Fontana, Fontana, Gustot, Jalan, Karvellas, Lee, Lee, Martinez, Medina-Caliz, Olson, Ostapowicz, Robles-Diaz, Rockey, Stickel, Stravitz, Zimmerman   +21 more
core   +2 more sources

Bismuth subcitrate, metronidazole and tetracycline – a rare cause of drug-induced liver injury

European Journal of Case Reports in Internal Medicine, 2023
Drug-induced liver injury (DILI) is a liver condition caused by any drug or toxic substance. The spectrum of DILI manifestations can range from asymptomatic elevation of liver enzymes to acute liver failure.
Carina Silva, Susana Merim, Rita Sevivas, João Mota, Alexandra Leitão   +4 more
doaj   +1 more source

Liver Enzyme Abnormalities and Associated Risk Factors in HIV Patients on Efavirenz-Based HAART with or without Tuberculosis Co-Infection in Tanzania. [PDF]

, 2012
To investigate the timing, incidence, clinical presentation, pharmacokinetics and pharmacogenetic predictors for antiretroviral and anti-tuberculosis drug induced liver injury (DILI) in HIV patients with or without TB co-infection.
A Habtewold, A Kwara, A Patel, A Tostmann, A Tostmann, A Tostmann, A Turkova, AK Daly, AM Anderson, B Lopman, BS Kappelhoff, C Benichou, C Nyakutira, CJ Hoffmann, CJ Hoffmann, D Voora, DF Wares, E Aklillu, E Aklillu, E Lopez-Lopez, E Ngaimisi, E Ngaimisi, E Pukenyte, Eleni Aklillu, Eliford Ngaimisi, Eric Sandstrom, Ferdinand Mugusi, G Yimer, G Yimer, G Yimer, GJ Dore, GL Dean, JG Stine, JJ Saukkonen, JK Mukonzo, JR Ungo, Juergen Burhenne, K Cohen, Klaus-Dieter Riedel, Lars Lindquist, LK Shipton, M Fiegenbaum, M Nelson, MI Matee, Mohamed Janabi, Muhammad Bakari, N Abrescia, N Soleman, Omary Minzi, P Kuehl, P Ocama, Petros C. Karakousis, R Kalyesubula, R Singla, RA Mirghani, S Russmann, Sabina Mugusi, SC Figueroa, SF Mugusi, V Gounden, W Mankhatitham, Z Desta, ZS Lamar   +62 more
core   +2 more sources

Adverse drug reaction and organ damage: the liver [PDF]

, 2016
Drug-induced liver injury (Dili) is among the most challenging acute or chronic liver conditions to be handled by physicians. Despite its low incidence in the general population, Dili is a frequent cause of acute liver failure.
LICATA, Anna
core   +1 more source

A Comprehensive Review on the Use of Herbal Dietary Supplements in the USA, Reasons for Their Use, and Review of Potential Hepatotoxicity

Livers, 2022
Herbal and dietary supplement (HDS) use has grown exponentially in the United States. Unfortunately, the incidence of HDS-related liver injury has proportionally increased.
Adnan Khan, Kashyap Chauhan, Heather Ross, Natalia Salinas Parra, John Magagna, Makala Wang, Patrick Zhu, Ryan Erwin, Dina Halegoua-DeMarzio   +8 more
doaj   +1 more source

Drug-induced liver injury [PDF]

, 2016
Drug-induced liver injury (DILI) remains the most common cause of acute liver failure (ALF) in the western world. Excluding paractamol overdose, nearly all DILI encountered in the clinical setting is idiosyncratic in nature, since affected individuals ...
A, Amacher, Chalasani, Chen, Chien, El Sherrif, Hillman, Maggi, Russo, Sakaan, Studniarz, Suk, Yeong   +12 more
core   +1 more source

Hepatotoxicity reports in the FDA adverse event reporting system database: A comparison of drugs that cause injury via mitochondrial or other mechanisms

Acta Pharmaceutica Sinica B, 2021
Drug-induced liver injury (DILI) is a leading reason for preclinical safety attrition and post-market drug withdrawals. Drug-induced mitochondrial toxicity has been shown to play an essential role in various forms of DILI, especially in idiosyncratic ...
Payal Rana, Michael D. Aleo, Xuerong Wen, Stephen Kogut   +3 more
doaj   +1 more source

Hepatitis E Virus Detection in Liver Tissue from Patients with Suspected Drug-Induced Liver Injury [PDF]

, 2015
Hepatitis E virus (HEV) infection is increasingly recognized as a cause of acute hepatitis in the industrialized world. We aimed to determine the frequency of acute Hepatitis E virus (HEV) infection in cases of suspected drug-induced liver injury (DILI),
Achim Weber, Erik Springer, Marion Bawohl, Obinna Chijioke   +3 more
core   +2 more sources