Results 91 to 100 of about 435,266 (312)

Trial-based Discrimination Procedure for Studying Drug Relapse in Rats

Bio-Protocol, 2019
In abstinent drug addicts, cues formerly associated with drug-taking experiences gain relapse-inducing potency (‘incubate’) over time. Animal models of incubation may help in developing treatments for relapse prevention.
Veronica Lennon, Megan Brenner, Sophia Weber, Lauren Komer, Rajtarun Madangopal   +4 more
doaj   +1 more source

Subjectivity and media production on drug addiction

, 2021
Milena Ribeiro Siqueira, Cezar Villaça Azeredo, Raphael Fonseca Braga de Melo, Rebecca Rodrigues Cedro de Brito, Érica H. Ribeiro-Andrade   +4 more
openalex   +1 more source

Effects of Oxytocin on Drug Addiction and Its Relationship to Prosocial Behavior [PDF]

, 2023

openalex   +1 more source

How government policy affects the consumption of hard drugs: The case of opium in Java, 1873-1907 [PDF]

ecomomic history;government policy;drug addiction;consumption;hard ...
Luijk, E.W. van, Ours, J.C. van
core   +1 more source

Hijacking translation in addiction. [PDF]

, 2016
Two studies suggest that the reduced activity of a translation initiation factor called eIF2α might be partly responsible for the increased risk of drug addiction seen in ...
Izquierdo, Alicia, Silva, Alcino J
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Romantic love v.s. drug addiction may inspire a new treatment for addiction

Frontiers in Psychology, 2016
Drug addiction is a complex neurological dysfunction induced by recurring drug intoxication. Strategies to prevent and treat drug addiction constitute a topic of research interest.
Zhiling Zou, Hongwen Song, Hongwen Song, Yuting Zhang, Xiaochu Zhang, Xiaochu Zhang, Xiaochu Zhang, Xiaochu Zhang   +7 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

How the Misunderstanding that Heroin Addiction Is a Choice and the Stigma Surrounding Medication-Assisted Treatment Leads to More Overdose Deaths

, 2018
Heroin is an opioid that commonly appears as white or brown powder. Eventually a person can become physically dependent on heroin, meaning the body begins to expect the drug.
Drew, Margaret M.
core  

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source