Comparative study of the potential of poly(2-ethyl-2-oxazoline) as carrier in the formulation of amorphous solid dispersions of poorly soluble drugs [PDF]
, 2019 Despite the fact that solid dispersions are gaining momentum, the number of polymers that have been used as a carrier during the past 50 years is rather limited.
Boel, Eline +5 more
core +1 more source
Solubility improvement of progesterone from solid dispersions prepared by solvent evaporation and co-milling [PDF]
, 2020 The aim of this contribution was to evaluate the impact of processing methods and polymeric carriers on the physicochemical properties of solid dispersions of the poorly soluble drug progesterone (PG). Five polymers: hydroxypropyl methylcellulose (HPMC),
Al-Obaidi, Hisham +3 more
core +1 more source
Characterization and cytotoxicty of nanostructured lipid carriers formulated with olive oil, hydrogenated palm oil and polysorbate 80. [PDF]
, 2013 Nanostructured lipid carriers (NLC) composed of solid and liquid lipids, and surfactants are potentially good colloidal drug carriers. Before NLC can be used as drug carriers, the cytotoxicity of their components must be ascertained.
Abbasalipourkabir, Roghayeh +2 more
core +1 more source
First-Principles Calculations on Monolayer WX2 (X = S, Se) as an Effective Drug Delivery Carrier for Anti- Tuberculosis Drugs [PDF]
arXiv, 2023 Tuberculosis (TB) remains a major global health concern, necessitating the exploration of novel drug delivery systems to combat the challenges posed by conventional approaches. We investigated the potential of monolayer transition metal dichalcogenides (TMDs) as an innovative platform for efficient and targeted delivery of antituberculosis drugs ...
arxiv
Intraocular drug delivery systems for Diabetic retinopathy: Current and future prospective [PDF]
BioImpactsIn pharmaceutical research and development, novel drug delivery systems represent a significant advancement aimed at enhancing the efficacy of therapeutic agents through innovative delivery mechanisms.
Sayed Latif Taheri +2 more
doaj +1 more source
Nanoparticles as carriers of proteins, peptides and other therapeutic molecules
Open Life Sciences, 2018 Nanoparticles have many applications both in industry and medicine. Depending upon their physical and chemical properties, they can be used as carriers of therapeutic molecules or as therapeutics.
Pudlarz Agnieszka, Szemraj Janusz
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Nanoparticles in the treatment of chronic lung diseases [PDF]
, 2019 Nanoparticles, although considered a topic of modern medicine, actually have an interesting history. Currently, advances in nanomedicine hold great promise as drug carrier systems for sustained release and targeted delivery of diverse therapeutic agents.
Alexescu, Teodora G +9 more
core +1 more source
An overview of the most important mechanisms and systems of targeted drug delivery [PDF]
بیولوژی کاربردی, 2016 Drug delivery is one of the most important and most complex pharmaceutical branch that today due to use of other sciences is expanding dramatically. These improvements, especially in the field of drug delivery mechanisms and systems is very effective and
سید محمدجواد حسینی زاده
doaj
New Approaches in Nanomedicine for Ischemic Stroke
Pharmaceutics, 2021 Ischemic stroke, caused by the interruption of blood flow to the brain and subsequent neuronal death, represents one of the main causes of disability in developed countries. Therapeutic methods such as recanalization approaches, neuroprotective drugs, or
Clara Correa-Paz +7 more
doaj +1 more source