Cancer DNA vaccines: current preclinical and clinical developments and future perspectives
Journal of Experimental & Clinical Cancer Research, 2019 The recent developments in immuno-oncology have opened an unprecedented avenue for the emergence of vaccine strategies. Therapeutic DNA cancer vaccines are now considered a very promising strategy to activate the immune system against cancer. In the past,
Alessandra Lopes +2 more
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Acta Pharmaceutica Sinica B, 2023 As known, the benefits of photothermal therapy (PTT) are greatly limited by the heat tolerance of cancer cells resulting from overexpressed heat shock proteins (HSPs). Then HSPs further trigger the formation of stress granules (SGs) that regulate protein
Fan Tong +11 more
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Microneedle for transdermal drug delivery: current trends and fabrication
Journal of Pharmaceutical Investigation, 2021 Transdermal delivery has the advantage of bypassing the first-pass effect and allowing sustained release of the drug. However, the drug delivery is limited owing to the barrier created by the stratum corneum.
J. Jung, S. Jin
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Validation of smart nanoparticles as controlled drug delivery systems: loading and pH-dependent release of pilocarpine [PDF]
, 2017 Micelles are good devices for use as controlled drug delivery systems because they exhibit the ability to protect the encapsulated substance from the routes of degradation until they reach the site of action. The present work assesses loading kinetics of
Galbis Fuster, Elsa +4 more
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Sizing nanomatter in biological fluids by fluorescence single particle tracking [PDF]
, 2010 Accurate sizing of nanoparticles in biological media is important for drug delivery and biomedical imaging applications since size directly influences the nanoparticle processing and nanotoxicity in vivo.
Angles-Cano, Eduardo +11 more
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Modulation of Methotrexate Release from Nano-Hydrogels via Drug-Transition Metal Complexation [PDF]
Trends in Pharmaceutical Sciences, 2020 Despite the extensive application of methotrexate (MTX) as a chemotherapeutic agent and an immune system suppressor, its therapeutic implementation has been limited due to its poor pharmacokinetics, saturable cellular transport, and insufficient response
Mahsa Taheri +5 more
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Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier.
Polymers, 2011 In past two decades poly lactic-co-glycolic acid (PLGA) has been among the most attractive polymeric candidates used to fabricate devices for drug delivery and tissue engineering applications.
Hirenkumar K. Makadia, S. Siegel
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Nanoparticle-Based Drug Delivery in Cancer Therapy and Its Role in Overcoming Drug Resistance
Frontiers in Molecular Biosciences, 2020 Nanotechnology has been extensively studied and exploited for cancer treatment as nanoparticles can play a significant role as a drug delivery system.
Yihan Yao +9 more
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Chitosan Glutamate-Coated Niosomes: a proposal for Nose-to-Brain delivery [PDF]
, 2018 The aim of this in vitro study is to prepare and characterize drug free and pentamidine loaded chitosan glutamate coated niosomes for intranasal drug delivery to reach the brain through intranasal delivery.
Angeloni, Livia +9 more
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Advances in oral transmucosal drug delivery [PDF]
, 2011 Original article can be found at : http://sciencedirect.com/ Copyright ElsevierThe successful delivery of drugs across the oral mucosa represents a continuing challenge, as well as a great opportunity.
Brown, Marc +2 more
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