Results 51 to 60 of about 466,787 (269)

Superparamagnetic Iron Oxide Nanoparticles Encapsulated in Biodegradable Thermosensitive Polymeric Micelles: Toward a Targeted Nanomedicine Suitable for Image-Guided Drug Delivery [PDF]

, 2009
Superparamagnetic iron oxide nanoparticles (SPIONs) have been receiving great attention lately due to their various biomedical applications, such as in MR imaging and image guided drug delivery.
Seevinck, P.R., Talelli, M., Dep Farmaceutische wetenschappen, van Nostrum, C.F., Rijcken, C.J.F., Lammers, T., Storm, G., Hennink, W.E., Advanced drug delivery systems/drug targeting   +8 more
core  

Local Drug Delivery in Bladder Cancer: Advances of Nano/Micro/Macro-Scale Drug Delivery Systems [PDF]

, 2023
Treatment of bladder cancer remains a critical unmet need and requires advanced approaches, particularly the development of local drug delivery systems. The physiology of the urinary bladder causes the main difficulties in the local treatment of bladder ...
Irina Marchenko, Daria Trushina
core   +1 more source

Identification of beagle food taking patterns and protocol for food effects evaluation on bioavailability

Scientific Reports, 2018
Food is a known primary role to the exposure of the drugs orally administered. Since each animal may have unique food taking pattern and it is difficult to manipulate the food taking to animals, there lacks rationalized protocol for the food effects in ...
Guoqing Zhang, Caifen Wang, Li Wu, Jian Xu, Xiaoxiao Hu, Shailendra Shakya, Yuanzhi He, Xiaohong Ren, Weidong Chen, Jiwen Zhang   +9 more
doaj   +1 more source

BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish‐Language mHealth Adherence Support App for Spanish‐Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens, Madeline R. Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin   +4 more
wiley   +1 more source

Polysaccharide drug delivery systems based on pectin and chitosan [PDF]

, 2010
Chitosans and pectins are natural polysaccharides which show great potential in drug delivery systems. Chitosans are a family of strongly polycationic derivatives of poly-N-acetyl-D-glucosamine.
Kok, M. S., Adams, G. G., Morris, Gordon, Harding, S. E.   +3 more
core  

Childhood Acute Lymphoblastic Leukemia Survival in Western Kenya: Reduction in Early Deaths and Treatment Abandonment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara, George Bogonko, Festus Njuguna, Sandra Langat, Martha Kipngetich, Dennis Njenga, Gertjan Johannes Kaspers, Terry Allen Vik   +7 more
wiley   +1 more source

Handbook of non-invasive drug delivery systems : science and technology / [PDF]

, 2009
With the improvements in formulation science and certain transdermal delivery technologies, the non-invasive mode of drug delivery is now ready to compete with traditional methods of oral and injectible routes of drug delivery.
Kulkarni, Vitthal S.
core  

Modulating nuclear stiffness and envelope barrier facilitates AAV nuclear entry and reduces immunogenicity

Nature Communications
Recombinant adeno-associated viruses (rAAVs) have shown promise for orthopedic diseases. However, conventional AAV vectors face major challenges, where immune responses reduce transgene efficacy and inadequate vector potency requires higher doses ...
Yangsen Ou, Fuhua Wu, Chunting He, Shuang Luo, Zhaofei Guo, Yongshun Zhang, Rui Hu, Yanhua Xu, Xue Tang, Yuanhao Zhao, Lin Ye, Xiaoyan Chen, Shuting Bai, Guangsheng Du, Xun Sun   +14 more
doaj   +1 more source

Implantable sandwich PHBHHx film for burst-free controlled delivery of thymopentin peptide

Acta Pharmaceutica Sinica B, 2018
Sustained release and non-parental formulations of peptides and protein drugs are highly desirable because of enhanced therapeutic effects as well as improved patient compliance. This is especially true for small peptides such as thymopentin (TP5).
Ke Peng, Chengyu Wu, Guoxu Wei, Jinghui Jiang, Zhirong Zhang, Xun Sun   +5 more
doaj   +1 more source

Scarless wound healing programmed by core-shell microneedles

Nature Communications, 2023
Effective reprogramming of chronic wound healing remains challenging due to the limited drug delivery efficacy hindered by physiological barriers, as well as the inappropriate dosing timing in distinct healing stages.
Ying Zhang, Shenqiang Wang, Yinxian Yang, Sheng Zhao, Jiahuan You, Junxia Wang, Jingwei Cai, Hao Wang, Jie Wang, Wei Zhang, Jicheng Yu, Chunmao Han, Yuqi Zhang, Zhen Gu   +13 more
doaj   +1 more source