Epidermal growth factor receptor: Target for delivery and silencing [PDF]
Epidermal growth factor receptor in cancer therapy Recently, cancer research has been able to identify molecular targets that are specific for (or highly expressed by) cancer cells.
Santos Oliveira, S. +2 more
core +1 more source
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager +8 more
wiley +1 more source
Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer–based drug delivery systems [PDF]
The direct intratumoral (i.t.) injection of anticancer agents has been evaluated extensively in the past few decades. Thus far, however, it has failed to become established as an alternative route of administration in routine clinical practice.
Ulbrich, K. +9 more
core +1 more source
Pulsed in vitro release and in vivo behavior of exploding microcapsules [PDF]
Drug delivery systems which can generate multiple drug pulses after a single injection can be of major importance for e.g. the delivery of vaccines which often require multiple booster injections to generate sufficient immunity.
De Smedt, Stefaan +11 more
core +1 more source
Nanomaterial-Based Drug Delivery Systems for Ischemic Stroke
Ischemic stroke is a leading cause of death and disability in the world. At present, reperfusion therapy and neuroprotective therapy, as guidelines for identifying effective and adjuvant treatment methods, are limited by treatment time windows, drug ...
Haimei Zhou +7 more
core +1 more source
Global Efforts to Reduce Paediatric Cancer Care Disparities in Radiotherapy: A Decade Change
ABSTRACT Background We present an update on the status, needs and challenges faced by paediatric imaging and radiotherapy (RT) programmes globally after a previous survey conducted by the International Atomic Energy Agency (IAEA) 10 years prior. Methods We developed and distributed a 121‐question survey to radiation oncologists, medical physicists and ...
Raymond B. Mailhot Vega +10 more
wiley +1 more source
Reduction-sensitive polymers and bioconjugates for biomedical applications [PDF]
Reduction-sensitive biodegradable polymers and conjugates have emerged as a fascinating class of biomedical materials that can be elegantly applied for intracellular triggered gene and drug delivery.
Meng, F.H. +4 more
core
Hydrogel Drug Delivery Systems for Bone Regeneration
With the in-depth understanding of bone regeneration mechanisms and the development of bone tissue engineering, a variety of scaffold carrier materials with desirable physicochemical properties and biological functions have recently emerged in the field ...
Jingang Xiao +6 more
core +1 more source
Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine +17 more
wiley +1 more source
Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers [PDF]
Copolymers of N-(2-hydroxypropyl)methacrylamide (HPMA) are prototypic and well-characterized polymeric drug carriers that have been broadly implemented in the delivery of anticancer therapeutics.
Ulbrich, K. +8 more
core

