Results 31 to 40 of about 464,584 (319)

Advances in Medical Devices for Augmented Acupuncture Therapy

Advanced Science
Acupuncture, as a traditional medicine applied worldwide, is considered an effective treatment for numerous chronic diseases. Many researches have explored the biological mechanisms of acupuncture, including the skin‐neuro‐immune axis and inflammation ...
Ruisi Cai, Chenyi Yu, Xinyi Luo, Ningyu Xu, Jicheng Yu, Xiao Ye, Yuqi Zhang, Zhen Gu   +7 more
doaj   +1 more source

Characterisation of 2-HP-β-cyclodextrin-PLGA nanoparticle complexes for potential use as ocular drug delivery vehicles

Artificial Cells, Nanomedicine, and Biotechnology, 2019
Aim 2-HP-β-cyclodextrin-PLGA nanoparticle complexes were prepared to enhance the aqueous humour delivery of Triamcinolone acetonide.Materials & methods Drug-loaded 2-HP-β-CD/PLGA nanoparticle complexes prepared by adapting a quasi-emulsion solvent ...
Fan Li, Yuqin Wen, Yan Zhang, Kangyu Zheng, Junfeng Ban, Qingchun Xie, Yifeng Wen, Qing Liu, Fohua Chen, Zhenjie Mo, Lizhong Liu, Yanzhong Chen, Zhufen Lu   +12 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Hydrogel Drug Delivery Systems for Bone Regeneration

, 2023
With the in-depth understanding of bone regeneration mechanisms and the development of bone tissue engineering, a variety of scaffold carrier materials with desirable physicochemical properties and biological functions have recently emerged in the field ...
Jingang Xiao, Yuping Xie, Maogeng Feng, Gang Tao, Shuyu Cai, Shuanglin Peng, Long Bai   +6 more
core   +1 more source

Mucoadhesive drug delivery systems

Journal of Pharmacy And Bioallied Sciences, 2011
Mucoadhesion is commonly defined as the adhesion between two materials, at least one of which is a mucosal surface. Over the past few decades, mucosal drug delivery has received a great deal of attention. Mucoadhesive dosage forms may be designed to enable prolonged retention at the site of application, providing a controlled rate of drug release for ...
Rahamatullah, Shaikh, Thakur, Raj Singh, Garland, M.J., Woolfson, David, Donnelly, Ryan   +4 more
openaire   +4 more sources

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Immunological Risk of Injectable Drug Delivery Systems [PDF]

, 2009
Injectable drug delivery systems (DDS) such as particulate carriers and water-soluble polymers are being used and developed for a wide variety of therapeutic applications.
Schellekens, H., Jiskoot, W., Huub Schellekens, Wim Jiskoot, Rianne M. F. van Schie, Myrra G. Carstens, Carstens, M.G., van Schie, R.M.F.   +7 more
core   +1 more source

Polymeric Drug Delivery Systems by Additive Manufacturing

, 2021
Additive manufacturing (AM) is gaining interests in drug delivery applications, offering innovative opportunities for the design and development of systems with complex geometry and programmed controlled release profile.
Borandeh, Sedigheh, Teotia, Arun, Seppälä, Jukka, van Bochove, Bas   +3 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source