Results 131 to 140 of about 401,429 (294)

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

open access: yesAdvanced Functional Materials, EarlyView.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta   +4 more
wiley   +1 more source

A Challenge for Diagnosing Acute Liver Injury with Concomitant/Sequential Exposure to Multiple Drugs: Can Causality Assessment Scales Be Utilized to Identify the Offending Drug?

open access: yesCase Reports in Pediatrics, 2014
Drug-induced hepatotoxicity most commonly manifests as an acute hepatitis syndrome and remains the leading cause of drug-induced death/mortality and the primary reason for withdrawal of drugs from the pharmaceutical market.
Roxanne Lim   +3 more
doaj   +1 more source

Injectable Dual‐Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration

open access: yesAdvanced Functional Materials, EarlyView.
A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui   +10 more
wiley   +1 more source

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati   +2 more
wiley   +1 more source

Cholestasis Linked to Bodybuilding Supplements: Exploring the Risks of Contamination

open access: yesCase Reports in Hepatology
Drug-induced liver injury resulting from herbal and dietary supplement use is increasingly common and underrecognized. We report a case of a 34-year-old male recreational bodybuilder who presented with muscle cramping, fatigue, and diffuse itching in the
Mark Matusak   +4 more
doaj   +1 more source

Novel Functional Materials via 3D Printing by Vat Photopolymerization

open access: yesAdvanced Functional Materials, EarlyView.
This Perspective systematically analyzes strategies for incorporating functionalities into 3D‐printed materials via Vat Photopolymerization (VP). It explores the spectrum of achievable functionalities in recently reported novel materials—such as conductive, energy‐storing, biodegradable, stimuli‐responsive, self‐healing, shape‐memory, biomaterials, and
Sergey S. Nechausov   +3 more
wiley   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat   +11 more
wiley   +1 more source

Empagliflozin-induced liver injury

open access: yesEuropean Journal of Case Reports in Internal Medicine
Background: Drug-induced liver injury is an uncommon, idiosyncratic adverse reaction with heterogeneous clinical presentations, ranging from asymptomatic transaminase elevations to acute liver failure.
Hélder Diogo Gonçalves   +6 more
doaj   +1 more source

Drug-induced chronic liver injury [PDF]

open access: yesJournal of Hepatology, 2018
Lara, Dakhoul   +2 more
openaire   +2 more sources

Laser Engineering of HfN‐Based Nanoparticles for Safe NIR‐I Photothermal and X‐ray Enhancing Cancer Therapies

open access: yesAdvanced Functional Materials, EarlyView.
In this study, we produced HfN‐based nanoparticles via femtosecond laser ablation in acetone. The nanoparticles exhibit a red‐shifted plasmonic resonance in the NIR‐I window, colloidal stability after coating with polyethyleneglycol, and excellent biocompatibility. The photothermal and X‐ray sensitization therapeutic effects were demonstrated for tumor
Julia S. Babkova   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy