Results 251 to 260 of about 404,775 (298)

Biomimetic Ru‐Mn Nanozyme with Cascade Catalytic Activity Attenuates Secondary Brain Injury in Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan   +8 more
wiley   +1 more source

[Research progress in the field of drug-induced liver injury in 2025]. [PDF]

open access: yesZhonghua Gan Zang Bing Za Zhi
Zhi Y, Dong YN, Lei XH, Mao YM.
europepmc   +1 more source

Oral Bioinspired Peroxisome‐Engineered Probiotics for Modulating Gut Microbiota Homeostasis and Alleviating Cardiac Chemotherapy Toxicity

open access: yesAdvanced Science, EarlyView.
This study developed an oral bioinspired peroxisome‐engineered probiotic (BPEP) by anchoring lipid‐encapsulated ruthenium nanozymes onto Escherichia coli Nissle 1917, utilizing probiotics to deliver nanozymes to the intestinal barrier for reactive oxygen species/reactive nitrogen species elimination, tight junction restoration, and gut microbiota ...
Shuyu Wang   +10 more
wiley   +1 more source

Idiosyncratic Drug-Induced Liver Injury and Trastuzumab Deruxtecan in Breast Cancer: A Case Report. [PDF]

open access: yesCurr Oncol
Lisanti C   +9 more
europepmc   +1 more source

[Gut microbiota-associated metabolites with drug-induced liver injury]. [PDF]

open access: yesZhonghua Gan Zang Bing Za Zhi
Gao WK   +5 more
europepmc   +1 more source

A Case Report: Drug-Induced Liver Injury from Prolonged Topical Application of Noni (<i>Morinda citrifolia</i>). [PDF]

open access: yesJ Investig Med High Impact Case Rep
Kim CJ   +6 more
europepmc   +1 more source
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Drug-Induced Liver Injury

Hospital Practice, 1978
In the usual course of events, the liver detoxifies hepatocytotoxic intermediates of drug metabolism. But when protective systems are overloaded by normally harmless drugs, the intermediates can cause massive, even fatal, hepatic necrosis.
J R, Mitchell, B H, Lauterburg
openaire   +2 more sources

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