Results 121 to 130 of about 2,205,477 (304)

Potensi Interaksi Obat Pada Pasien Gangguan Ginjal Kronis di Instalasi Rawat Inap RSUD Dr. Moewardi Tahun 2014 [PDF]

open access: yes, 2016
Chronic kidney disease (CKD) is a condition which characterized by a gradual loss of kidney function accompanied by manifestations of kidney pathology abnormality for at least three months. Patients with chronic kidney disease who have some complications
Khasanah, Rizqi Nurul
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Opportunities and Challenges of Using Big Data to Detect Drug-Drug Interaction Risk [PDF]

open access: yes, 2019
Chasioti D.   +1 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Pantoprazole – safety in drug-drug interaction

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2012
The aim of review. To carry out comparative analysis of metabolic pathways of proton pump inhibitors (PPI), to determine the agent with lowest effect on activity of cytochrome CYP2C19 isoenzyme for improvement of safety of combined treatment by ...
E. V. Shikh, D. A. Sychev
doaj  

Te Aka Roa o Te Oranga, the far reaching vines of wellness: The development of a framework to evaluate alcohol and drug treatment for Māori [PDF]

open access: yes, 2003
The impact of alcohol and other drug problems for Māori is well documented. Substance use has been implicated in a range of physical and mental health problems, and a variety of negative social statistics such as high rates of imprisonment.
Armstrong, Pam   +6 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Physicians’ awareness and use of drug-drug interactions software: A preliminary study

open access: yesIbom Medical Journal
Background: Drug-drug interactions software is used as a tool to investigate clinically harmful interactions. Prescribers need to be aware of these tools to improve the quality of drug prescriptions, thus ensuring better patient care.
Oriaifo OG, Opadeyi AO, Isah AO
doaj   +1 more source

Maternal Drug Addiction: Influences on mother-child relationship and on early child development. [PDF]

open access: yes, 2016
Much literature has pointed out parental drug addiction as a risk factor at multiple levels for the dyad, affecting parenting quality, child development and more globally the adult-child relationship.
DE PALO, Francesca   +2 more
core  

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