Results 81 to 90 of about 1,107,910 (309)
Assessing the potential for drug interactions [PDF]
, 2017 Understanding the potential for adverse drug reactions (ADRs), resulting from plant-drug interactions,is a key aspect of medicinal plant safety. The aim of this study was to provide an in-depth assessment of standardised extracts of Hyptis verticillata ...
Picking, D. +5 more
core
Ultra-High to Ultra-Low Drug Loaded Micelles: Probing Host-Guest Interactions by Fluorescence Spectroscopy [PDF]
, 2019 Polymer micelles are an attractive means to solubilize water insoluble compounds such as drugs. Drug loading, formulations stability and control over drug release are crucial factors for drug loaded polymer micelles.
Michael M, Lübtow +5 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Journal of CheminformaticsIn drug development, managing interactions such as drug–drug, drug–disease, and drug–nutrient is critical for ensuring the safety and efficacy of pharmacological treatments.
Nour H. Marzouk +4 more
doaj +1 more source
Drug-drug interactions : from knowledge base to clinical impact [PDF]
, 2014 Drug usage has increased steadily, and the more drugs used, the higher the risk for adverse effects or loss of effect due to drug-drug interactions. For drug prescribers it is difficult to know what drugs a patient is taking and whether they interact ...
Marine Andersson (18690100)
core
A drug-drug conditioning paradigm reveals multiple antipsychotic-nicotine interactions [PDF]
, 2017 Clinical studies indicate a reciprocal impact between nicotine use and antipsychotic medications in patients with schizophrenia. The present study used a conditioned avoidance response (CAR) test (a behavioral test of antipsychotic effect) and examined
Li, Ming +3 more
core +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Measuring drug similarity using drug–drug interactions
Quantitative BiologyCombination therapy is a promising approach to address the challenge of antimicrobial resistance, and computational models have been proposed for predicting drug–drug interactions.
Ji Lv +4 more
doaj +1 more source
Drug Interactions of Direct-Acting Oral Anticoagulants [PDF]
, 2016 In recent years, new direct-acting oral anticoagulants (DOACs) have been introduced into clinical practice that specifically inhibit either factor Ia or Xa.
Howes, Laurence +2 more
core +1 more source