Results 1 to 10 of about 7,785,599 (366)
Therapeutic drug monitoring—antiepileptic drugs [PDF]
British Journal of Clinical Pharmacology, 1998 Aims To provide a brief critical review of the basis and contemporary practice of monitoring the concentrations of antiepileptic drugs in biological fluids. Methods The review is based on literature data and observations from clinical practice.
M. J. Eadie
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Therapeutic drug monitoring of immunosuppressant drugs [PDF]
British Journal of Clinical Pharmacology, 1999 Individualizing a patient’s drug therapy to obtain the optimum balance between therapeutic efficacy and the occurrence of adverse events is the physician’s goal. However, achieving this goal is not always straight forward, being complicated by within and between patient variability in both pharmacokinetics and pharmacodynamics.
A. E. Johnston, David W. Holt
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Pediatric Neurology Briefs, 1995 The appropriateness of antiepileptic drug (AED) level monitoring was assessed in a tertiary care center performing more than 10,000 AED level determinations per year and reported from the Brigham and Womens Hospital, Boston, MA.
J Gordon Millichap
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online quantitative analysis, online process mass spectrometer, quadrupole mass spectrometer [PDF]
Zhipu Xuebao, 2023 As of October 2022, the United Nations Office on Drugs and Crime (UNODC) Early Warning Advisory (EWA) has monitored over 1 150 new psychoactive substances (NPS) that had appeared in 137 countries and territories, including 76 substances that were ...
LIU Cui-mei1 +5 more
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Impact of COVID-19 on drug markets, use, harms and drug services in Europe
Journal of Geography, Politics and Society, 2022 Since early 2020, the COVID-19 pandemic has had a dramatic impact on the way we live, with European countries having to introduce unprecedented measures to protect public health. As with all areas of life, drug consumption, related harms and drug markets
Alessandro Pirona +12 more
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From Therapeutic Drug Monitoring to Model‐Informed Precision Dosing for Antibiotics
Clinical pharmacology and therapy, 2021 Therapeutic drug monitoring (TDM) and model‐informed precision dosing (MIPD) have evolved as important tools to inform rational dosing of antibiotics in individual patients with infections.
S. Wicha +6 more
semanticscholar +1 more source
Therapeutic Drug Monitoring, 2021 When mycophenolic acid (MPA) was originally marketed for immunosuppressive therapy, fixed doses were recommended by the manufacturer. Awareness of the potential for a more personalized dosing has led to development of methods to estimate MPA area under ...
S. Bergan +37 more
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Molecules, 2022 Lenvatinib is a multi-targeted tyrosine kinase inhibitor that inhibits tumor angiogenesis, but hypertension is the most common adverse reaction. Telmisartan is an angiotensin receptor blocker used to treat hypertension.
Yanjun Cui +6 more
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Journal of the American Medical Association (JAMA), 2021 Importance Proactive therapeutic drug monitoring (TDM), defined as individualized drug dosing based on scheduled monitoring of serum drug levels, has been proposed as an alternative to standard therapy to maximize efficacy and safety of infliximab and ...
S. W. Syversen +32 more
semanticscholar +1 more source
Molecules, 2022 Sorafenib (SOR), an inhibitor of multiple kinases, is a classic targeted drug for advanced hepatocellular carcinoma (HCC) which often coexists with type 2 diabetes mellitus (T2DM). Dapagliflozin (DAPA), a sodium–glucose cotransporter-2 inhibitor (SGLT2i),
Xueru He +6 more
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