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Predictive Performance of Bayesian Methods to Forecast Vancomycin Concentration for Therapeutic Drug Monitoring in Critically Ill Pediatric Patients [PDF]
PharmaceuticsBackground: This study aimed to evaluate different Bayesian algorithms and the first-order pharmacokinetics (PK) equation approach for forecasting vancomycin concentrations in critically ill pediatric patients and to identify influencing factors. Methods:
Ha T. Pham +11 more
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online quantitative analysis, online process mass spectrometer, quadrupole mass spectrometer [PDF]
Zhipu Xuebao, 2023 As of October 2022, the United Nations Office on Drugs and Crime (UNODC) Early Warning Advisory (EWA) has monitored over 1 150 new psychoactive substances (NPS) that had appeared in 137 countries and territories, including 76 substances that were ...
LIU Cui-mei1 +5 more
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Impact of COVID-19 on drug markets, use, harms and drug services in Europe
Journal of Geography, Politics and Society, 2022 Since early 2020, the COVID-19 pandemic has had a dramatic impact on the way we live, with European countries having to introduce unprecedented measures to protect public health. As with all areas of life, drug consumption, related harms and drug markets
Alessandro Pirona +12 more
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Molecules, 2022 Lenvatinib is a multi-targeted tyrosine kinase inhibitor that inhibits tumor angiogenesis, but hypertension is the most common adverse reaction. Telmisartan is an angiotensin receptor blocker used to treat hypertension.
Yanjun Cui +6 more
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Molecules, 2022 Sorafenib (SOR), an inhibitor of multiple kinases, is a classic targeted drug for advanced hepatocellular carcinoma (HCC) which often coexists with type 2 diabetes mellitus (T2DM). Dapagliflozin (DAPA), a sodium–glucose cotransporter-2 inhibitor (SGLT2i),
Xueru He +6 more
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Pharmacokinetic Interactions between Canagliflozin and Sorafenib or Lenvatinib in Rats
Molecules, 2022 Hepatocellular carcinoma (HCC) and type 2 diabetes mellitus (T2DM) are common clinical conditions, and T2DM is an independent risk factor for HCC. Sorafenib and lenvatinib, two multi-targeted tyrosine kinase inhibitors, are first-line therapies for ...
Yanjun Cui +5 more
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Pharmaceutical Biology, 2022 Context Atorvastatin (ATV) and QiShenYiQi pills (QSYQ), a Chinese patent medicine, are often co-prescribed to Chinese cardiovascular patients. The effects of QSYQ on the pharmacokinetics of ATV have not been studied.
Congyang Ding +8 more
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Molecules, 2022 The third-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), osimertinib, aumolertinib, and furmonertinib represent a new treatment option for patients with EGFR p.Thr790 Met (T790 M)-mutated non-small cell lung cancer ...
Ying Li +6 more
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Fayixue Zazhi, 2022 ObjectiveTo analyze the chemical structure of the interfering substance that affects the result of methamphetamine analysis in wastewater.MethodsA combination of GC-MS and liquid chromatography-quadrupole time-of-flight mass spectrometry （LC-QTOF-MS） was
ZHANG Ting-ting +4 more
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Monitoring drug adherence [PDF]
Transplantation Reviews, 2015 Medication nonadherence is prevalent in transplant recipients and is a major reason for graft loss. The present review discusses the measurement of adherence in transplant recipients and strategies to improve adherence. SOURCES REVIEWED: Since adherence research is not confined to transplant recipients, our literature review included studies relevant ...
Sarah R, Lieber +2 more
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