Frontiers in Pharmacology, 2022 Objective: With increasing numbers of biosimilars entering the market or in the approval pipeline in China, understanding the current awareness and attitudes of biosimilars still remains the first step to promote uptake.
Yang Hu +17 more
doaj +1 more source
Metabolites, 2022 Galangin, a naturally available flavonoid, induces a variety of pharmacological activities and biological effects via several mechanisms. However, in vivo metabolism of galangin has not been fully explored, which means knowledge of its pharmacodynamics ...
Feng Zhao +5 more
doaj +1 more source
Determination of itraconazole and hydroxyitraconazole in plasma by use of liquid chromatography-tandem mass spectrometry with on-line solid-phase extraction [PDF]
, 2003 In this paper a method for the simultaneous quantification of the anti-fungal drug itraconazole and its co-active metabolite hydroxyitraconazole in plasma employing liquid chromatography tandem-mass spectrometry and automated solid-phase extraction is ...
Schiel, Xaver +2 more
core +1 more source
Challenges and Opportunities for the Implementation of Virological Testing in resource-limited settings [PDF]
, 2012 Though the advantages of routine virological monitoring for patients on anti-retroviral therapy have been established, cost and complexity limit its full implementation.
Bartlett +22 more
core +3 more sources
Food and Agricultural Immunology, 2022 A decoction is the most common form of Chinese herbal medicine dosing. An Angelica sinensis decoction was qualitatively and semi-quantitatively analyzed for 15 highly toxic pesticide residues by thermal desorption electrospray ionization mass ...
Hongyan Zhang +7 more
doaj +1 more source
Synthetic Drug Production in Belgium – Environmental Harms as Collateral Damage?
Journal of Illicit Economies and Development, 2021 The production of illicit drugs contributes to important environmental harms. In the European context, the production of synthetic drugs, particularly MDMA and amphetamine (and more recently methamphetamine), increasingly poses environmental challenges ...
Mafalda Pardal +2 more
doaj +1 more source
Timeliness of Clinic Attendance is a good predictor of Virological Response and Resistance to Antiretroviral drugs in HIV-infected patients [PDF]
, 2012 Ensuring long-term adherence to therapy is essential for the success of HIV treatment. As access to viral load monitoring and genotyping is poor in resource-limited settings, a simple tool to monitor adherence is needed.
A Ammassari +28 more
core +4 more sources
Quantifying Isoniazid Levels in Small Hair Samples: A Novel Method for Assessing Adherence during the Treatment of Latent and Active Tuberculosis. [PDF]
, 2016 BackgroundTuberculosis (TB) is the leading cause of death from an infectious pathogen worldwide and the most prevalent opportunistic infection in people living with HIV.
Bacchetti, Peter +6 more
core +1 more source
A lab-on-a-disc platform enables serial monitoring of individual CTCs associated with tumor progression during EGFR-targeted therapy for patients with NSCLC [PDF]
, 2020 Rationale: Unlike traditional biopsy, liquid biopsy, which is a largely non-invasive diagnostic and monitoring tool, can be performed more frequently to better track tumors and mutations over time and to validate the efficiency of a cancer treatment ...
Cho, Yoon-Kyoung +9 more
core +1 more source
Toward therapeutic drug monitoring of citalopram in depression? Insights from a systematic review
Frontiers in Psychiatry, 2023 BackgroundWithin the framework of individualized psychopharmacotherapy, therapeutic drug monitoring (TDM) has gained increasing relevance. In the absence of high-quality evidence, the TDM of citalopram (CIT) and the recommended therapeutic ranges of the ...
Na Xu +10 more
doaj +1 more source