Results 41 to 50 of about 1,484,823 (337)

Simultaneous Determination of 15 Mycotoxins in Grains by Solid Phase Extraction with Impurity Adsorption and UPLC/MSMS

open access: yesLiang you shipin ke-ji, 2021
To establish a method for the simultaneous determination of 15 mycotoxins in grains by ultra performance liquid chromatography tandem mass spectrometry (UPLC/MSMS).
LIU Xiao-xiao   +6 more
doaj   +1 more source

The Role of Genetic Polymorphisms in High-Dose Methotrexate Toxicity and Response in Hematological Malignancies: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Pharmacology, 2021
Objective: High-dose methotrexate (HDMTX) is a mainstay therapeutic agent for the treatment of diverse hematological malignancies, and it plays a significant role in interindividual variability regarding the pharmacokinetics and toxicity.
Zaiwei Song   +20 more
doaj   +1 more source

Genetic and genomic approaches for the discovery of parasite genes involved in antimalarial drug resistance [PDF]

open access: yes, 2013
The biggest threat to the war on malaria is the continued evolution of drug resistance by the parasite. Resistance to almost all currently available antimalarials now exists in Plasmodium falciparum which causes the most suffering among all human malaria
Mwangi, J.M., Ranford-Cartwright, L.C.
core   +1 more source

Age Differences in Psychoactive Substance Abuse in Population of the Republic of Belarus

open access: yesCentral European Journal of Sport Sciences and Medicine, 2016
Background. The recent epidemiological studies conducted in Belarus point to a fall in the average age of registered drug abusers and in the age of drug use onset, an increasing proportion of injecting drugs, and addicted persons.
Vladimir Lelevich   +3 more
doaj   +1 more source

Study on the Mass Spectrometry Fragmentation Patterns for Rapid Screening and Structure Identification of Ketamine Analogues in Illicit Powders

open access: yesMolecules, 2023
Ketamine analogues have been emerging in recent years and are causing severe health and social problems worldwide. Ketamine analogues use 2-phenyl-2-aminocyclohexanone as the basic structure and achieve physiological reactions similar to or even more ...
Yilei Fan   +5 more
doaj   +1 more source

Individualized immunosuppression in transplant patients: potential role of pharmacogenetics. [PDF]

open access: yes, 2012
The immunosuppressive drugs used to prevent the rejection of transplanted organs have a narrow therapeutic index. Under treatment results in episodes of rejection leading to either damage or loss of the organ. Over immunosuppression increases the risk of
Abboudi, H, Macphee, IA
core   +2 more sources

Therapeutic drug monitoring [PDF]

open access: yesCurrent Opinion in Anaesthesiology, 2002
Traditionally, therapeutic drug monitoring has been used for the management of epilepsy, cardiac arrhythmias, asthma and depression. This review provides an update, particularly for the newer clinical applications, and how therapeutic drug monitoring (including use of analytical and interpretation tools) can improve clinical outcomes.Improved drug ...
Gillian M, Shenfield, Raymond G, Morris
openaire   +4 more sources

The impact of clinical pharmacists’ intervention on the rational use of intravenous paracetamol vials in Baghdad Teaching Hospital: A case-control study [PDF]

open access: yesPharmacia
Paracetamol has been recognized worldwide as a safe and effective agent for relieving pain and reducing fever in many patients. This study aimed to investigate the role of clinical pharmacist interventions in the rational and appropriate use of ...
Kawthar Faris Nassir   +7 more
doaj   +3 more sources

Knowledge, Attitudes and Practice of Healthcare Providers, Healthcare Regulatory Practitioners and Patients Toward Biosimilars in China: Insights From a Nationwide Survey

open access: yesFrontiers in Pharmacology, 2022
Objective: With increasing numbers of biosimilars entering the market or in the approval pipeline in China, understanding the current awareness and attitudes of biosimilars still remains the first step to promote uptake.
Yang Hu   +17 more
doaj   +1 more source

From clinical application to cognitive enhancement: the example of methylphenidate [PDF]

open access: yes, 2016
Methylphenidate (MPD) is a central nervous system (CNS) stimulant, which belongs to the phenethylamine group and is mainly used in the treatment of attention deficit hyperactive disorder (ADHD).
Busardo', FRANCESCO PAOLO   +4 more
core   +1 more source

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