Results 221 to 230 of about 915,020 (267)
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Fabrication of porous, drug‐releasing, biodegradable, polymer scaffolds for sustained drug release
Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2008AbstractTwo different approaches were used to fabricate porous scaffolds, and their in vitro drug releasing characteristics were examined. In the first method, a poly(L‐lactic acid) (PLLA) solution and poly(vinyl alcohol) (PVA) + acetaminophen solution was homogenized. The emulsion was then blended with a PLLA solution in chloroform.
Mayur, Uttarwar, Pranesh, Aswath
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Intraocular Sustained Drug Release Devices
Archives of Ophthalmology, 1995The articleon treatment of cytomegalovirus (CMV) retinitis with an intraocular sustained-release ganciclovir implant by Martin et al 1 in the December 1994 issue of theArchivesrepresents an important breakthrough. Past studies indicate that CMV retinitis occurs in 20% to 25% of all persons with the acquired immunodeficiency syndrome (AIDS); Douglass ...
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Timed Release from Polymeric Films Containing Drugs and Kinetics of Drug Release
Journal of Pharmaceutical Sciences, 1975The preparation of cast films of ethylcellulose containing caffeine and salicylic acid is described. These films exhibit timed release of drugs. Release rates were found to agree with both the classical first-order equation (log drug retained against time) and diffusion-controlled release models, as exemplified by Higuchi's equations (drug release ...
M, Donbrow, M, Friedman
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Controlled Drug Release from Polymers
Hospital Practice, 1978Unlike conventional routes of drug administration, controlled-release systems that use implanted, inserted, or surface-applied noninflammatory polymeric vehicles can deliver a steady quantity of drug to a target area over long periods of time. This is now true for drugs of both high and low molecular weight.
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Chronopharmacology and controlled drug release
Expert Opinion on Drug Delivery, 2005Circadian rhythms in the body are well established and are an important factor to consider when administering drugs. Many diseases display symptoms and onset characteristics that are not randomly distributed within 24 h (e.g., coronary infarction, angina pectoris, asthmatic attacks and peptic ulcer perforations); therefore, it is not surprising that ...
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Drug release through liposome pores
Colloids and Surfaces B: Biointerfaces, 2015Electrical, ultrasound and other types of external fields are known to induce the formation of pores in cellular and model membranes. This paper examines drug release through field induced liposome pores using Monte Carlo simulations. We find that drug release rates vary as a function of pore size and spacing, as well as the overall fraction of surface
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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Paolo Tarantino +2 more
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Clinical translation of long-acting drug delivery formulations
Nature Reviews Materials, 2022Wei Li, Dennis Lee, Thomas R Tice
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