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Drug resistance and combating drug resistance in cancer
Cancer Drug Resistance, 2019 Cancer is the second leading cause of death in the US. Current major treatments for cancer management include surgery, cytotoxic chemotherapy, targeted therapy, radiation therapy, endocrine therapy and immunotherapy.
Xuan Wang, Haiyun Zhang, Xiaozhuo Chen
semanticscholar +4 more sources
Potential of nanopore sequencing for tuberculosis diagnosis and drug resistance detection [PDF]
BMC Infectious DiseasesObjectives This study evaluates the effectiveness of nanopore sequencing for accurate detection of Mycobacterium tuberculosis pathogens and drug resistance mutations in clinical specimens.
Fei Ren +8 more
doaj +2 more sources
The Different Mechanisms of Cancer Drug Resistance: A Brief Review
Advanced Pharmaceutical Bulletin, 2017 Anticancer drugs resistance is a complex process that arises from altering in the drug targets. Advances in the DNA microarray, proteomics technology and the development of targeted therapies provide the new strategies to overcome the drug resistance ...
Behzad Mansoori +2 more
exaly +2 more sources
Microbiology Spectrum, 2023 With the application of bedaquiline (Bdq), the success rate of multidrug-resistant tuberculosis (MDR-TB) treatment has been significantly improved; however, the cardiac safety of the patients during treatment cannot be ignored. Hence, this study compared
Rong Li +6 more
doaj +1 more source
malERA: An updated research agenda for insecticide and drug resistance in malaria elimination and eradication. [PDF]
PLoS Medicine, 2017 Resistance to first-line treatments for Plasmodium falciparum malaria and the insecticides used for Anopheles vector control are threatening malaria elimination efforts. Suboptimal responses to drugs and insecticides are both spreading geographically and
malERA Refresh Consultative Panel on Insecticide and Drug Resistance
doaj +1 more source
A Review: Understanding Molecular Mechanisms of Antibody-Dependent Enhancement in Viral Infections
Vaccines, 2023 Antibody Dependent Enhancement (ADE) of an infection has been of interest in the investigation of many viruses. It is associated with the severity of the infection.
Jyoti Sawant, Ajit Patil, Swarali Kurle
doaj +1 more source
BMC Infectious Diseases, 2023 Background The World Health Organization has reported that the treatment success rate of multi-drug resistance tuberculosis is approximately 57% globally. Although new drugs such as bedaquiline and linezolid is likely improve the treatment outcome, there
J-B Ma +9 more
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Molecular Mechanisms of Drug Resistance in Staphylococcus aureus
International Journal of Molecular Sciences, 2022 This paper discusses the mechanisms of S. aureus drug resistance including: (1) introduction. (2) resistance to beta-lactam antibiotics, with particular emphasis on the mec genes found in the Staphylococcaceae family, the structure and occurrence of ...
B. Młynarczyk-bonikowska +3 more
semanticscholar +1 more source