Results 11 to 20 of about 328,364 (290)

Modeling microbial drug-resistance: from mathematics to pharmacoeconomics

Фармакоэкономика, 2018
Complicated intra-abdominal infection (IAI) requires increased health care expenditures and additional resources to compensate for an ineffective starting therapy.Aim. To select the economically optimal algorithm for using antimicrobial agents (AMA) that
Yu. M. Gomon, M. A. Arepyeva, Yu. E. Balykina, A. S. Kolbin, A. A. Kurylev, M. A. Proskurin, S. V. Sidorenko   +6 more
doaj   +4 more sources

Microbial Persistence and the Road to Drug Resistance [PDF]

Cell Host & Microbe, 2013
Microbial drug persistence is a widespread phenomenon in which a subpopulation of microorganisms is able to survive antimicrobial treatment without acquiring resistance-conferring genetic changes. Microbial persisters can cause recurrent or intractable infections, and, like resistant mutants, they carry an increasing clinical burden.
Michael A. Lobritz, James J. Collins, Nadia Cohen   +2 more
openaire   +3 more sources

Overcoming Multidrug Resistance of Antibiotics via Nanodelivery Systems

Pharmaceutics, 2022
Antibiotic resistance has become a threat to microbial therapies nowadays. The conventional approaches possess several limitations to combat microbial infections.
Mohammad Imran, Saurav Kumar Jha, Nazeer Hasan, Areeba Insaf, Jitendra Shrestha, Jesus Shrestha, Hari Prasad Devkota, Salman Khan, Nisha Panth, Majid Ebrahimi Warkiani, Kamal Dua, Philip M. Hansbro, Keshav Raj Paudel, Yousuf Mohammed   +13 more
doaj   +1 more source

Chronic arsenic exposure and microbial drug resistance [PDF]

Proceedings of the National Academy of Sciences, 2013
Resistance to antimicrobial drugs represents one of the greatest threats to the control of infectious diseases and is a particular problem in treating diseases caused by parasitic protists. These pathogens are of enormous medical importance, causing diseases such as malaria, toxoplasmosis, trypanosomiasis, and leishmaniasis. In the absence of effective
Malcolm J. McConville, Stuart A. Ralph
openaire   +3 more sources

The Impact of Triclosan on the Spread of Antibiotic Resistance in the Environment [PDF]

, 2015
Triclosan (TCS) is a commonly used antimicrobial agent that enters wastewater treatment plants (WWTPs) and the environment. An estimated 1.1 × 105 to 4.2 × 105 kg of TCS are discharged from these WWTPs per year in the United States.
Carey, Daniel E., McNamara, Patrick J.
core   +7 more sources

Multimodal Role of Amino Acids in Microbial Control and Drug Development

Antibiotics, 2020
Amino acids are ubiquitous vital biomolecules found in all kinds of living organisms including those in the microbial world. They are utilised as nutrients and control many biological functions in microorganisms such as cell division, cell wall formation,
Muhammad Idrees, Afzal R. Mohammad, Nazira Karodia, Ayesha Rahman   +3 more
doaj   +1 more source

Drug Resistance in Eukaryotic Microorganisms [PDF]

, 2016
Eukaryotic microbial pathogens are major contributors to illness and death globally. Although much of their impact can be controlled by drug therapy as with prokaryotic microorganisms, the emergence of drug resistance has threatened these treatment ...
A Abdolrasouli, A Cassone, A Chowdhary, A Ecker, A Heinberg, A Kulshrestha, A Mbengue, A Mukherjee, A Selmecki, A Selmecki, A Trochine, AC Coelho, AF Cowman, AF Cowman, AH Fairlamb, AH Fairlamb, AJ Kazibwe, AM Abd-Alla, AM Dondorp, AM Mejia, AY Sokolova, B Chawla, B Gourbal, B Zingales, BD Alexander, BJ Kullberg, BK Kubata, BM Mony, BS Hall, BS Hall, BS McGwire, C Amaratunga, C Amaratunga, C Brochu, C Costa, C Mathieu, C Sisowath, C Wongsrichanalai, CA Morillo, CD Goodman, CF Oliva, CP Sanchez, CP Sanchez, D Begolo, D Rojo, DA Fidock, DS Guttery, DS Perlin, DW Denning, E Castanys-Munoz, E Chatelain, E Kussell, E Matovu, E Shor, E Snelders, E Snelders, E Vermeulen, E Wang, F Ariey, F Nosten, FC Odds, FE Graf, FE Graf, FJ Perez-Victoria, FJ Perez-Victoria, FJ Perez-Victoria, FM Fernandez, G Awasthi, G Blum, G Priotto, GA Canuto, GA Pankey, GM Nayyar, GW Rose, H Noedl, HL Callahan, HM Andrade, HY Sun, I Keren, I Molina, IH Cheeseman, IM Vincent, IM Vincent, IM Vincent, J Hemingway, J Robays, J Song, J Straimer, J Yuan, JA Urbina, JA Urbina, JC Dias, JC Dias, JC Munday, JC Wootton, JI Manzano, JL Nishikawa, JM Perez-Victoria, JR Franco, JW van der Linden, K El Fadili, K Lewis, K Seifert, KC Gray, KJ Kwon-Chung, KW Dantzler, L Denoeud-Ndam, L Glover, LE Cowen, LE Cowen, M Berg, M Ghorbal, M Maharjan, M Manske, M Plourde, M Rakotomanga, M Rakotomanga, M Venkatesan, M Woolhouse, M Woolhouse, MA Pfaller, MB Rogers, MC Brotherton, MD LaFleur, MD LaFleur, MK Kinga, MK Laufer, MR Perry, MR Perry, MR Perry, MT Duraisingh, MT Ferdig, N Baker, N Biyani, N Marquis, N Regev-Rudzki, N Rovira-Graells, NJ White, NR Cohen, NS Carter, O Epaulard, O Miotto, P Baiocco, P Maser, P Shaked-Mishan, P Vandeputte, P Wang, PE Verweij, PJ Hotez, PK Fyfe, PL Olliaro, PP Pyana, PY Mantel, R Kumar, R Mukhopadhyay, R Prasad, RD Cannon, S Alsford, S Decuypere, S Decuypere, S Dey, S Dey, S Imhof, S Kucharikova, S Leroux, S Mandal, S Mok, S Patterson, S Pelleau, S Pulcini, S Rijal, S Sundar, S Sundar, S Takala-Harrison, S Wyllie, S Wyllie, S Wyllie, S Wyllie, SA Flowers, SC Welburn, SD Singh, SE Kidd, SG Valderramos, SK Katiyar, SMF Murta, SR Meshnick, SR Wilkinson, TE Wellems, TE Wellems, TPC Dorlo, V Lutje, W Peters, Y Sterkers, Y Zhou   +193 more
core   +4 more sources

Inulin Can Alleviate Metabolism Disorders in ob/ob Mice by Partially Restoring Leptin-related Pathways Mediated by Gut Microbiota

Genomics, Proteomics & Bioinformatics, 2019
Inulin has been used as a prebiotic to alleviate glucose and lipid metabolism disorders in mice and humans by modulating the gut microbiota. However, the mechanism underlying the alleviation of metabolic disorders by inulin through interactions between ...
Xiaofeng Song, Liang Zhong, Na Lyu, Fei Liu, Boxing Li, Yanan Hao, Yong Xue, Jing Li, Yuqing Feng, Yue Ma, Yongfei Hu, Baoli Zhu   +11 more
doaj   +1 more source

Model Systems of Human Intestinal Flora, to Set Acceptable Daily Intakes of Antimicrobial Residues [PDF]

, 2000
The veterinary use of antimicrobial drugs in food producing animals may result in residues in food, that might modify the consumer gut flora. This review compares three model systems that maintain a complex flora of human origin: (i) human flora ...
Cemiglia CE, Corpet DE, Corpet DE Antibiotic residues and drug resistance in human intestinal flora, Corpet DE Antibiotic resistance from food, Corpet DE Current status of models for testing antibiotic residues, Freter R, Licht TR, Rollins LD, Tancrede C, Vollaard El   +9 more
core   +2 more sources

State of Knowledge on the Acquisition, Diversity, Interspecies Attribution and Spread of Antimicrobial Resistance between Humans, Animals and the Environment: A Systematic Review

Antibiotics, 2022
Resistance to antibiotics is considered one of the most urgent global public health concerns. It has considerable impacts on health and the economy, being responsible for the failure to treat infectious diseases, higher morbidity and mortality rates, and
Hélène Meier, Keira Spinner, Lisa Crump, Esther Kuenzli, Gertraud Schuepbach, Jakob Zinsstag   +5 more
doaj   +1 more source