Results 11 to 20 of about 2,035 (168)

Inulin Can Alleviate Metabolism Disorders in ob/ob Mice by Partially Restoring Leptin-related Pathways Mediated by Gut Microbiota

Genomics, Proteomics & Bioinformatics, 2019
Inulin has been used as a prebiotic to alleviate glucose and lipid metabolism disorders in mice and humans by modulating the gut microbiota. However, the mechanism underlying the alleviation of metabolic disorders by inulin through interactions between ...
Xiaofeng Song, Liang Zhong, Na Lyu, Fei Liu, Boxing Li, Yanan Hao, Yong Xue, Jing Li, Yuqing Feng, Yue Ma, Yongfei Hu, Baoli Zhu   +11 more
doaj   +1 more source

State of Knowledge on the Acquisition, Diversity, Interspecies Attribution and Spread of Antimicrobial Resistance between Humans, Animals and the Environment: A Systematic Review

Antibiotics, 2022
Resistance to antibiotics is considered one of the most urgent global public health concerns. It has considerable impacts on health and the economy, being responsible for the failure to treat infectious diseases, higher morbidity and mortality rates, and
Hélène Meier, Keira Spinner, Lisa Crump, Esther Kuenzli, Gertraud Schuepbach, Jakob Zinsstag   +5 more
doaj   +1 more source

Antimicrobial profile of Acinetobacter baumannii at a tertiary hospital in Honduras: a cross-sectional analysis

Revista Panamericana de Salud Pública, 2020
Acinetobacter baumannii is considered to be a worldwide threat to public health due to its high antimicrobial resistance rates and the severe infections it can cause. Little is known about this pathogen’s resistance in Central America.
Julio Cesar Zuniga-Moya, Clerk Annette Caballero, Mariela Loucel-Linares, Mayra Jazmin Benitez, Edoardo Zambrano-Garcia, Lidice Vanesa Fajardo, Julissa Stephanie Paz, Suyapa A Bejarano, Emilio Barrueto Saavedra, Luis Enrique Romero   +9 more
doaj   +1 more source

Exploring Phytochemicals for Combating Antibiotic Resistance in Microbial Pathogens

Frontiers in Pharmacology, 2021
Antibiotic resistance or microbial drug resistance is emerging as a serious threat to human healthcare globally, and the multidrug-resistant (MDR) strains are imposing major hurdles to the progression of drug discovery programs.
Tushar Khare, Tushar Khare, Uttpal Anand, Abhijit Dey, Yehuda G. Assaraf, Zhe-Sheng Chen, Zhijun Liu, Vinay Kumar, Vinay Kumar   +8 more
doaj   +1 more source

Biological properties of the major causes factors of purulently inflammatory diseases of surgical patients in Zaporizhzhia Clinical Hospital of Emergency and Critical Care Medicine

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
The problem of antibiotic resistance of purulent-inflammatory diseases pathogens that arise in patients during treatment in surgery units is urgent and requires a thorough knowledge of the spectrum of circulating strains of microorganisms and changes in ...
N. M. Polishchuck, D. L. Kyryk, I. Ye. Yurchuk, O. M. Filippova, T. M. Lischenko, S. V. Yehorova   +5 more
doaj   +1 more source

Transcriptional response to the host cell environment of a multidrug-resistant Mycobacterium tuberculosis clonal outbreak Beijing strain reveals its pathogenic features

Scientific Reports, 2021
Tuberculosis is a global public health problem with emergence of multidrug-resistant infections. Previous epidemiological studies of tuberculosis in Thailand have identified a clonal outbreak multidrug-resistant strain of Mycobacterium tuberculosis in ...
Pakorn Aiewsakun, Pinidphon Prombutara, Tegar Adriansyah Putra Siregar, Thanida Laopanupong, Phongthon Kanjanasirirat, Tanawadee Khumpanied, Suparerk Borwornpinyo, Pirut Tong-Ngam, Alisa Tubsuwan, Prapaporn Srilohasin, Angkana Chaiprasert, Wuthiwat Ruangchai, Prasit Palittapongarnpim, Therdsak Prammananan, Brian C. VanderVen, Marisa Ponpuak   +15 more
doaj   +1 more source

Modeling microbial drug-resistance: from mathematics to pharmacoeconomics

Фармакоэкономика, 2018
Complicated intra-abdominal infection (IAI) requires increased health care expenditures and additional resources to compensate for an ineffective starting therapy.Aim. To select the economically optimal algorithm for using antimicrobial agents (AMA) that
Yu. M. Gomon, M. A. Arepyeva, Yu. E. Balykina, A. S. Kolbin, A. A. Kurylev, M. A. Proskurin, S. V. Sidorenko   +6 more
doaj   +1 more source

Advancing Antimicrobial Resistance Research Through Quantitative Modeling and Synthetic Biology

Frontiers in Bioengineering and Biotechnology, 2020
Antimicrobial resistance (AMR) is an emerging global health crisis that is undermining advances in modern medicine and, if unmitigated, threatens to kill 10 million people per year worldwide by 2050.
Kevin S. Farquhar, Harold Flohr, Daniel A. Charlebois   +2 more
doaj   +1 more source

Prevalence of Extended-Spectrum β-lactamase and Integron Gene Carriage in Multidrug-Resistant Klebsiella Species Isolated from Outpatients in Yazd, Iran [PDF]

Iranian Journal of Medical Sciences, 2020
Background: Community-acquired infections by multidrug-resistant (MDR), extended-spectrum β-lactamase (ESBL) producing Klebsiella species (Klebsiella spp.) is of major concern worldwide. Antibiotic resistance, production of extended-spectrum β-lactamases
Mohammad Reza Malekjamshidi, Hengameh Zandi, Fereshteh Eftekhar   +2 more
doaj   +1 more source

A review on lipid-based nanocarriers mimicking chylomicron and their potential in drug delivery and targeting infectious and cancerous diseases

AAPS Open, 2023
Infectious and cancerous diseases are tedious to manage. The problem of drug resistance is often associated with anti-microbial and anti-cancer agents and is one of the most significant challenges that restrict their activity.
Rana E. Elnady, Maha M. Amin, Mohamed Y. Zakaria   +2 more
doaj   +1 more source