Results 111 to 120 of about 2,071,500 (370)

Management of Multiple Drug-Resistant Infections [PDF]

Journal of Antimicrobial Chemotherapy, 2004
Part I: Gram-Positive Bacteria Management of Community-Acquired Pneumonia Caused by Drug-Resistant Streptococcus pneumoniae Eric L. Nuermberger and William R. Bishai Management of Meningitis Caused by Resistant Streptococcus pneumoniae P. Fernandez Viladrich Emerging Resistance to Vancomycin, Rifampin, and Fluoroquinolones in Streptococcus pneumoniae ...
  +7 more sources

ANALYSIS OF THE PATIENTS REFERRED FOR TREATMENT TO NOVOSIBIRSK TUBERCULOSIS RESEARCH INSTITUTE FROM THE AREAS SUPERVISED BY THIS INSTITUTE. CHANGES IN CHEMOTHERAPY EFFICIENCY AFTER INTRODUCTION OF THE UPDATED TREATMENT REGIMENS AND MICROBIOLOGICAL DIAGNOSTICS

Туберкулез и болезни лёгких, 2017
In 2015 the implementation of Edicts no. 951 by the Russian Ministry of Health On Guidelines on Improvement of Respiratory Tuberculosis Treatment and Diagnostics was started.Goal of the study: to analyze the characteristics of tuberculosis patients ...
E. P. Myshkova, E. M. Zhukova, T. A. Reykhrud   +2 more
doaj   +1 more source

Noncoding RNAs in gastric cancer: implications for drug resistance

Molecular Cancer, 2020
Gastric cancer is the fourth most common malignancy and the third leading cause of cancer-related deaths worldwide. Advanced gastric cancer patients can notably benefit from chemotherapy including adriamycin, platinum drugs, 5-fluorouracil, vincristine ...
Ling Wei, Jujie Sun, Nasha Zhang, Yan Zheng, Xing-wu Wang, L. Lv, Jiandong Liu, Yeyang Xu, Yue Shen, Ming Yang   +9 more
semanticscholar   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Knowledge and Attitude of Students on Antimicrobial Resistance at Debre Markos University, Ethiopia [PDF]

, 2016
Irrational use of medicines is a key reason for the increase and spread of antimicrobial resistance and it is a global concern. It is a fast mounting universal crisis. The main of this study of this study was to assess knowledge, attitude and practice of
Bizuayehu, H. M. (Habtamu), Zelellw, D. A. (Desalegne)   +1 more
core  

EXPERIENCE OF USING BEDAQUILINE IN THE TREATMENT OF PULMONARY TUBERCULOSIS PATIENTS WITH MULTIPLE ANDEXTENSIVE DRUG RESISTANCE

Туберкулез и болезни лёгких, 2018
The article presents the evaluation of safety and efficiency of chemotherapy regimens including the new anti-tuberculosis agent of bedaquiline in 21 pulmonary tuberculosis patients with multiple and extensive drug resistance who were treated in Stavropol
N. M. Konovаlovа, V. S. Odinets, T. I. Vаsilenko, T. A. Zаdremаylovа   +3 more
doaj   +1 more source

Irreversible evolution, obstacles in fitness landscapes and persistent drug resistance [PDF]

arXiv, 2023
We use fitness graphs, or directed cube graphs, for analyzing evolutionary reversibility. The main application is antimicrobial drug resistance. Reversible drug resistance has been observed both clinically and experimentally. If drug resistance depends on a single point mutation, then a possible scenario is that the mutation reverts back to the wild ...
arxiv  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Multiple drug resistance in Candida albicans.

Acta Biochimica Polonica, 1995
By functional complementation of a PDR 5 (pleiotropic drug resistance) null mutant of S. cerevisiae, we have recently cloned and sequenced a multidrug resistance gene CDR 1 (Candida Drug Resistance). Transformation by CDR 1 of a PDR 5 disrupted host hypersensitive to cycloheximide and chloramphenicol resulted in resistance to these as well as other ...
R, Prasad, S K, Murthy, V, Gupta, R, Prasad   +3 more
openaire   +4 more sources

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source