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HIV drug resistance, viral suppression, and survival in children living with HIV in Brazil
HIV MedicineAbstractIntroductionMutations associated with HIV drug resistance (DR) affect clinical outcomes. Understanding the prevalence of HIV DR and its association with viral suppression and survival in the paediatric population is key to inform patient care and health policies.MethodsWe used Brazilian monitoring systems to identify genotyping tests performed ...
Alexandre A. C. Mendes‐Ferreira +5 more
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Structure and Dynamics of Viral Substrate Recognition and Drug Resistance: A Dissertation
2013Drug resistance is a major problem in quickly evolving diseases, including the human immunodeficiency (HIV) and hepatitis C viral (HCV) infections. The viral proteases (HIV protease and HCV NS3/4A protease) are primary drug targets. At the molecular level, drug resistance reflects a subtle change in the balance of molecular recognition; the drug ...
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Drug combination therapy for emerging viral diseases
Drug Discovery Today, 2021Zeenat A Shyr +2 more
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Repurposing of approved drug molecules for viral infectious diseases: a molecular modelling approach
Journal of Biomolecular Structure and Dynamics, 2022Nandan Kumar, G Narahari Sastry
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HIV viral resistance to antiretroviral drugs: foreword
Scandinavian Journal of Infectious Diseases, 2003openaire +2 more sources
Drug-Induced vs. Viral Maculopapular Exanthem—Resolving the Dilemma
Dermatopathology (Basel, Switzerland), 2022Sujay Khandpur, Rhea Ahuja
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Host-directed therapies for bacterial and viral infections
Nature Reviews Drug Discovery, 2017Stefan H E Kaufmann +2 more
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