Results 31 to 40 of about 8,375,389 (400)
Nanoparticle-Based Drug Delivery in Cancer Therapy and Its Role in Overcoming Drug Resistance
Frontiers in Molecular Biosciences, 2020 Nanotechnology has been extensively studied and exploited for cancer treatment as nanoparticles can play a significant role as a drug delivery system.
Yihan Yao +9 more
semanticscholar +1 more source
Apoptosis Deregulation and the Development of Cancer Multi-Drug Resistance
Cancers, 2021 Simple Summary Despite recent therapeutic advances against cancer, many patients do not respond well or respond poorly, to treatment and develop resistance to more than one anti-cancer drug, a term called multi-drug resistance (MDR).
C. Neophytou +3 more
semanticscholar +1 more source
Hypoxia, Metabolic Reprogramming, and Drug Resistance in Liver Cancer
Cells, 2021 Hypoxia, low oxygen (O2) level, is a hallmark of solid cancers, especially hepatocellular carcinoma (HCC), one of the most common and fatal cancers worldwide. Hypoxia contributes to drug resistance in cancer through various molecular mechanisms.
Macus Hao-Ran Bao, C. C. Wong
semanticscholar +1 more source
Survival outcomes of autologous breast reconstruction after mastectomy: A matched case-control study
Frontiers in Oncology, 2023 BackgroundDue to the lack of strong evidence-based medical evidence, the relationship between autologous breast reconstruction (ABR) after mastectomy and long-term prognosis is unclear.
Shang Wu +11 more
doaj +1 more source
Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer. [PDF]
, 2019 Although targeted therapies often elicit profound initial patient responses, these effects are transient due to residual disease leading to acquired resistance.
A Hübner +66 more
core +1 more source
Pharmacological Reviews, 2020 Epilepsy is a chronic neurologic disorder that affects over 70 million people worldwide. Despite the availability of over 20 antiseizure drugs (ASDs) for symptomatic treatment of epileptic seizures, about one-third of patients with epilepsy have seizures
W. Löscher +3 more
semanticscholar +1 more source
Resisting Bacterial Drug Resistance [PDF]
Chemistry & Biology, 2003 In this issue of Chemistry & Biology, Wright and colleagues report an elegant method for inhibiting enzymes critical for rendering bacteria drug resistant. By using cationic peptides as inhibitors, the authors have exploited two antibacterial mechanisms, making it doubly difficult for microbial retaliation.
openaire +3 more sources
Genetic and genomic approaches for the discovery of parasite genes involved in antimalarial drug resistance [PDF]
, 2013 The biggest threat to the war on malaria is the continued evolution of drug resistance by the parasite. Resistance to almost all currently available antimalarials now exists in Plasmodium falciparum which causes the most suffering among all human malaria
Mwangi, J.M., Ranford-Cartwright, L.C.
core +1 more source
Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond.
Chemical Reviews, 2020 Fungal infections are a major contributor to infectious disease-related deaths across the globe. Candida species are among the most common causes of invasive mycotic disease, with Candida albicans reigning as the leading cause of invasive candidiasis ...
Yunjin Lee +3 more
semanticscholar +1 more source
Drug resistant tuberculosis [PDF]
BMJ, 1995 EDITOR,—Concern is growing over the spread of drug resistant Mycobacterium tuberculosis. New evidence suggests that this spread may be increasing in certain sections of the British population. The recent advances in molecular techniques have equipped us with the means to make substantial inroads into the possible impact of drug resistant tuberculosis.1
openaire +6 more sources