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Drug safety in pregnancy. [PDF]

open access: yesAust Prescr
Drugs can affect the fetus in various ways, with the timing of exposure during pregnancy a key factor in determining both if and how a drug will impact a developing fetus. The exclusion of women of childbearing age from clinical trials, and the challenges in conducting large epidemiological studies, have resulted in a paucity of data on the fetal and ...
Kennedy D, Batagol R.
europepmc   +3 more sources

Points to consider for COVID-19 vaccine quality control and national lot release in Republic of Korea: focus on a viral vector platform [PDF]

open access: yesOsong Public Health and Research Perspectives, 2022
Due to the global public health crisis caused by the coronavirus disease 2019 (COVID-19) pandemic, the importance of vaccine development has increased. In particular, a rapid supply of vaccines and prompt deployment of vaccination programs are essential ...
Jung Hun Ju   +10 more
doaj   +1 more source

Determination of Residual Triflumezopyrim Insecticide in Agricultural Products through a Modified QuEChERS Method

open access: yesFoods, 2021
A rapid and simple analytical method for triflumezopyrim, a new class of mesoionic insecticides and commercialized molecules from DuPont, was developed with a modified QuEChERS method.
Sung-Min Cho   +9 more
doaj   +1 more source

Establishment of analysis method for the quantification of residues of halquinol and its metabolites in livestock and fishery products using liquid chromatography–tandem mass spectrometry

open access: yesApplied Biological Chemistry, 2023
In this study, an analysis method was established for the quantification of residues of halquinol and its metabolites in livestock and fishery products using liquid chromatography–tandem mass spectrometry (LC–MS/MS).
Tae Ho Lee   +4 more
doaj   +1 more source

Determination of Modified QuEChERS Method for Chlorothalonil Analysis in Agricultural Products Using Gas Chromatography–Mass Spectrometry (GC-MS/MS)

open access: yesFoods, 2023
Chlorothalonil is an organochlorine fungicide that blocks the respiratory process of cells and persists in agricultural products because it is used extensively to prevent fungal diseases. An analytical method of chlorothalonil using the modified QuEChERS
Da-Young Yun   +4 more
doaj   +1 more source

Risk of genital and urinary tract infections associated with SGLT‐2 inhibitors as an add‐on therapy to metformin in patients with type 2 diabetes mellitus: A retrospective cohort study in Korea

open access: yesPharmacology Research & Perspectives, 2022
Sodium‐glucose cotransporter‐2 (SGLT‐2) inhibitors are antidiabetic drugs with associated safety concerns regarding the risk of genital and urinary tract infections.
Hyeri Yang   +6 more
doaj   +1 more source

The complete chloroplast genome sequence of three medicinal species; Curcuma longa, Curcuma wenyujin, and Curcuma phaeocaulis (Zingiberaceae)

open access: yesMitochondrial DNA. Part B. Resources, 2021
Curcuma longa, C. wenyujin and C. phaeocaulis are important herbal medicine which of rhizomatous herbaceous perennial plant of the family Zingiberaceae.
Min-Kyeoung Kim   +5 more
doaj   +1 more source

Skin Sensitization Evaluation of Carbon-Based Graphene Nanoplatelets

open access: yesToxics, 2021
Graphene nanoplatelets (GNPs) are one of the major types of carbon based nanomaterials that have different industrial and biomedical applications. There is a risk of exposure to GNP material in individuals involved in their large-scale production and in ...
Sung-Hyun Kim   +9 more
doaj   +1 more source

o-Aminoazotoluene, 7,12-dimethylbenz[a]anthracene, and N-ethyl-N-nitrosourea, which are mutagenic but not carcinogenic in the colon, rapidly induce colonic tumors in mice with dextran sulfate sodium-induced colitis

open access: yesGenes and Environment, 2022
Background Several rodent models with chemically induced colon cancer have been developed. Among these models, dextran sulfate sodium (DSS), a colitis inducer, combined with azoxymethane as a colon mutagenic carcinogen, is commonly used.
Atsushi Hakura   +4 more
doaj   +1 more source

The Research of Toxicity and Sensitization Potential of PEGylated Silver and Gold Nanomaterials

open access: yesToxics, 2021
Polyethylene glycol (PEG) is a polymer used for surface modification of important substances in the modern pharmaceutical industry and biopharmaceutical fields.
Dong-Han Lee   +7 more
doaj   +1 more source

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