Results 21 to 30 of about 5,794,088 (264)

Skin Sensitization Evaluation of Carbon-Based Graphene Nanoplatelets

Toxics, 2021
Graphene nanoplatelets (GNPs) are one of the major types of carbon based nanomaterials that have different industrial and biomedical applications. There is a risk of exposure to GNP material in individuals involved in their large-scale production and in ...
Sung-Hyun Kim, So-Hye Hong, Jin Hee Lee, Dong Han Lee, Kikyung Jung, Jun-Young Yang, Hyo-Sook Shin, JeongPyo Lee, Jayoung Jeong, Jae-Ho Oh   +9 more
doaj   +1 more source

UnCorrupt SMILES: a novel approach to de novo design

Journal of Cheminformatics, 2023
Generative deep learning models have emerged as a powerful approach for de novo drug design as they aid researchers in finding new molecules with desired properties.
Linde Schoenmaker, Olivier J. M. Béquignon, Willem Jespers, Gerard J. P. van Westen   +3 more
doaj   +1 more source

Deciphering the scopolamine challenge rat model by preclinical functional MRI

Scientific Reports, 2021
During preclinical drug testing, the systemic administration of scopolamine (SCO), a cholinergic antagonist, is widely used. However, it suffers important limitations, like non-specific behavioural effects partly due to its peripheral side-effects ...
Gergely Somogyi, Dávid Hlatky, Tamás Spisák, Zsófia Spisák, Gabriella Nyitrai, András Czurkó   +5 more
doaj   +1 more source

Skin Sensitization Potential and Cellular ROS-Induced Cytotoxicity of Silica Nanoparticles

Nanomaterials, 2021
Nowadays, various industries using nanomaterials are growing rapidly, and in particular, as the commercialization and use of nanomaterials increase in the cosmetic field, the possibility of exposure of nanomaterials to the skin of product producers and ...
Sung-Hyun Kim, Dong Han Lee, SeoYoon Choi, Jun-Young Yang, Kikyung Jung, Jayoung Jeong, Jae Ho Oh, Jin Hee Lee   +7 more
doaj   +1 more source

Prevalence and Characteristics of Antimicrobial-Resistant Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus from Retail Meat in Korea

Food Science of Animal Resources, 2020
This study was to investigate the prevalence and characteristics of antimicrobial-resistant Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) from 4,264 retail meat samples including beef, pork, and chicken in Korea between 2013 and 2018 ...
Yong Hoon Kim, Han Sol Kim, Seokhwan Kim, Migyeong Kim, Hyo Sun Kwak   +4 more
doaj   +1 more source

Legacy data sharing to improve drug safety assessment

, 2022
S.811-812The sharing of legacy preclinical safety data among pharmaceutical companies and its integration with other information sources offers unprecedented opportunities to improve the early assessment of drug safety. Here, we discuss the experience of
Pognan, F., Saiz, J., Sajot, N., Lammens, L., Ecker, G.F., Kleinöder, T., Cronin, M.T.D., Northeved, H., Muster, W., Vermeulen, N.P.E., Escher, S., Jacques, P., Wichard, J., Brookes, A.J., Yang, C., Amberg, A., Vock, E., Brunak, S., Pinches, M., Valencia, A., Wolber, G., Hersey, A., Lei,, J. van der, Briggs, K., Díaz, C., Sanz, F., Steger-Hartmann, T., Pastor, M., Greene, N., Mestres, J., Marc, P., Cases, M., Beaumont, M., Zamora, I., Watson, D.K., Guzmán, A.   +35 more
core   +1 more source

Illicit drug use and awareness of health and policing initiatives at Australian music festivals among people who regularly use ecstasy and other illicit stimulants [PDF]

, 2019
There is significant concern about patron safety at music festivals, and particularly related to illicit drug use and associated harms. People who attend music festivals are more likely to report illicit drug use than the general population, and ...
Degenhardt, Louisa ; https://orcid.org/, Dietze, Paul, Lenton, Simon R, Hughes, Caitlin, Sutherland, Rachel ; https://orcid.org/, Sutherland, Rachel, Barratt, Monica ; https://orcid.org/, Ezard, Nadine, Salom, Caroline ; https://orcid.org/, Dietze, Paul ; https://orcid.org/, Degenhardt, Louisa, Bruno, Raimondo ; https://orcid.org/, Hill, Penny, Griggs, Jodie, Hughes, Caitlin ; https://orcid.org/, Peacock, Amy ; https://orcid.org/, Gibbs, Daisy, Salom, Caroline, Barrett, Monica, Bruno, Raimondo, Grigg, Jodie, Ezard, Nadine ; https://orcid.org/, Lenton, Simon ; https://orcid.org/, Gibbs, Daisy ; https://orcid.org/, Peacock, Amy   +24 more
core   +1 more source

Effect of Pulmonary Inflammation by Surface Functionalization of Zinc Oxide Nanoparticles

Toxics, 2021
Zinc oxide nanoparticles (ZnO NPs) are used in various industries such as food additives, cosmetics, and biomedical applications. In this study, we evaluated lung damage over time by three types of ZnO NPs (L-serine, citrate, and pristine) following the ...
Ayoung Jung, Sung-Hyun Kim, Jun-Young Yang, Jayoung Jeong, Jong Kwon Lee, Jae-Ho Oh, Jin Hee Lee   +6 more
doaj   +1 more source

Analysis of 13 Banned Colorants in Cosmetics via Liquid Chromatographic and Mass Spectrometric Techniques

Applied Sciences, 2023
Even though synthetic colorants can cause side effects such as allergies and pigmentation, they have not been sufficiently researched. Herein, high-performance liquid chromatography, liquid chromatography-tandem mass spectrometry, and liquid ...
Kyoung-Moon Han, You Kyung Kim, Sowoon Seo, Jun Hyoung Kim, Ji Hyun Lee, Hyung Il Kim, Sooyeul Cho   +6 more
doaj   +1 more source

Safety implications of combined antiretroviral and antituberculosis drugs [PDF]

, 2019
Introduction:Antiretroviral and anti-tuberculosis (TB) drugs are often co-administered in people living with HIV (PLWH). Early initiation of antiretroviral therapy (ART) during TB treatment improves survival in patients with advanced HIV disease ...
Wasserman, Sean, Bracchi, Margherita, Cohen, Karen, Meintjes, Graeme, Cerrone, Maddalena, Pozniak, Anton, Wilkinson, Robert J, Anton Pozniak, Margherita Bracchi, Robert J Wilkinson, Graeme Meintjes, Karen Cohen, Sean Wasserman, Maddalena Cerrone   +13 more
core   +1 more source