Results 31 to 40 of about 8,234,358 (305)

Analysis of 13 Banned Colorants in Cosmetics via Liquid Chromatographic and Mass Spectrometric Techniques

Applied Sciences, 2023
Even though synthetic colorants can cause side effects such as allergies and pigmentation, they have not been sufficiently researched. Herein, high-performance liquid chromatography, liquid chromatography-tandem mass spectrometry, and liquid ...
Kyoung-Moon Han, You Kyung Kim, Sowoon Seo, Jun Hyoung Kim, Ji Hyun Lee, Hyung Il Kim, Sooyeul Cho   +6 more
doaj   +1 more source

Systematic review of spontaneous reports of myocarditis and pericarditis in transplant recipients and immunocompromised patients following COVID-19 mRNA vaccination

BMJ Open, 2022
Objectives To determine whether spontaneous reporting rates of myocarditis and pericarditis differed in immunocompromised patients compared with the whole population overall, and in terms of demographics, vaccine dose and time-to-onset.Design Systematic ...
Saad Shakir, Samantha Lane, Alison Yeomans   +2 more
doaj   +1 more source

Use of real‐world evidence from healthcare utilization data to evaluate drug safety during pregnancy

Pharmacoepidemiology and Drug Safety, 2019
Because preapproval clinical trials typically exclude pregnant women, the evidence on drug safety during pregnancy required to inform drug labeling must come from postapproval controlled observational studies.
K. Huybrechts, B. Bateman, S. Hernández-Díaz   +2 more
semanticscholar   +1 more source

Reports of myocarditis and pericarditis following mRNA COVID-19 vaccination: a systematic review of spontaneously reported data from the UK, Europe and the USA and of the scientific literature

BMJ Open, 2022
Objectives To combine spontaneously reported data from multiple countries to estimate reporting rate, and better understand risk factors for myocarditis and pericarditis following COVID-19 messenger RNA (mRNA) vaccines.Design Systematic review of ...
Saad Shakir, Samantha Lane, Alison Yeomans   +2 more
doaj   +1 more source

3DDPDs: describing protein dynamics for proteochemometric bioactivity prediction. A case for (mutant) G protein-coupled receptors

Journal of Cheminformatics, 2023
Proteochemometric (PCM) modelling is a powerful computational drug discovery tool used in bioactivity prediction of potential drug candidates relying on both chemical and protein information.
Marina Gorostiola González, Remco L. van den Broek, Thomas G. M. Braun, Magdalini Chatzopoulou, Willem Jespers, Adriaan P. IJzerman, Laura H. Heitman, Gerard J. P. van Westen   +7 more
doaj   +1 more source

Establishment of the MID‐NET® medical information database network as a reliable and valuable database for drug safety assessments in Japan

Pharmacoepidemiology and Drug Safety, 2019
To establish a new medical information database network (designated MID‐NET®) to provide real‐world data for drug safety assessments in Japan.
M. Yamaguchi, Satomi Inomata, Sayoko Harada, Yusuke Matsuzaki, Maiko Kawaguchi, Mayuko Ujibe, Mari Kishiba, Yoshiaki Fujimura, M. Kimura, K. Murata, N. Nakashima, M. Nakayama, K. Ohe, T. Orii, Eizaburo Sueoka, Takahiro Suzuki, H. Yokoi, Fumitaka Takahashi, Y. Uyama   +18 more
semanticscholar   +1 more source

Expression of Concern to: Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatoxicity

Molecular Medicine, 2020
The Editors-in-Chief would like to alert readers that this article [1] is part of an investigation being conducted by the journal following the conclusions of an institutional enquiry at the University of Liverpool with respect to the quantitative mass ...
Daniel James Antoine, Dominic P. Williams, Anja Kipar, Hugh Laverty, B. Kevin Park   +4 more
doaj   +1 more source

Adverse Drug Reactions in Children: Pediatric Pharmacy and Drug Safety.

The Journal of Pediatric Pharmacology and Therapeutics, 2019
An underappreciated problem in child health is the risk for adverse drug reactions (ADRs). While there is an impression that children are at a lower risk than adults for ADRs, in fact a number of factors germane to pediatric therapy place certain groups ...
M. Rieder
semanticscholar   +1 more source

The REporting of A Disproportionality Analysis for DrUg Safety Signal Detection Using Individual Case Safety Reports in PharmacoVigilance (READUS-PV): Explanation and Elaboration

Drug Safety
In pharmacovigilance, disproportionality analyses based on individual case safety reports are widely used to detect safety signals. Unfortunately, publishing disproportionality analyses lacks specific guidelines, often leading to incomplete and ambiguous
M. Fusaroli, Francesco Salvo, Bernard Bégaud, T. Alshammari, Andrew Bate, V. Battini, Andreas Brueckner, G. Candore, Carla Carnovale, Salvatore Crisafulli, P. Cutroneo, Charles Dolladille, M. Drici, J. Faillie, Adam Goldman, M. Hauben, M. T. Herdeiro, Olivia Mahaux, Katrin Manlik, François Montastruc, Yoshihiro Noguchi, G. N. Norén, Roberta Noseda, Igho J Onakpoya, Antoine Pariente, E. Poluzzi, Myriam Salem, D. Sartori, N. T. Trinh, Marco Tuccori, Florence van Hunsel, E. V. van Puijenbroek, Emanuel Raschi, C. Khouri   +33 more
semanticscholar   +1 more source

DrugEx v3: scaffold-constrained drug design with graph transformer-based reinforcement learning

Journal of Cheminformatics, 2023
Rational drug design often starts from specific scaffolds to which side chains/substituents are added or modified due to the large drug-like chemical space available to search for novel drug-like molecules.
Xuhan Liu, Kai Ye, Herman W. T. van Vlijmen, Adriaan P. IJzerman, Gerard J. P. van Westen   +4 more
doaj   +1 more source