Results 31 to 40 of about 2,040,970 (208)

Safety of antiobesity drugs [PDF]

Therapeutic Advances in Drug Safety, 2013
Obesity is a major health problem worldwide. Although diet and physical activity are crucial in the management of obesity, the long-term success rate is low. Therefore antiobesity drugs are of great interest, especially when lifestyle modification has failed.
Cheung, TT, SAMARANAYAKE, NR, Cheung, BMY   +2 more
openaire   +4 more sources

The Influence of Safety, Efficacy, and Medical Condition Severity on Natural v. Synthetic Drug Preference

, 2016
Research indicates that there is a preference for natural v. synthetic products, but the influence of this preference on drug choice in the medical domain is largely unknown.
Lappas, Courtney M., Meier, Brian P.
core   +1 more source

A study of the dopamine transporter using the TRACT assay, a novel in vitro tool for solute carrier drug discovery

Scientific Reports, 2021
Members of the solute carrier (SLC) transporter protein family are increasingly recognized as therapeutic drug targets. The majority of drug screening assays for SLCs are based on the uptake of radiolabeled or fluorescent substrates.
Hubert J. Sijben, Julie J. E. van den Berg, Jeremy D. Broekhuis, Adriaan P. IJzerman, Laura H. Heitman   +4 more
doaj   +1 more source

Rewarding and Reinforcing Effects of 25H-NBOMe in Rodents

Brain Sciences, 2022
The drug 25H-NBOMe is a new psychoactive substance (NPS). The use of these substances is likely to pose a threat to public health because they elicit effects similar to those of known psychoactive substances with similar chemical structures.
Cheolmin Jo, Hyejin Joo, Dong-Hyun Youn, Jin Mook Kim, Young-Ki Hong, Na Young Lim, Kwan Soo Kim, Su-Jeong Park, Sun Ok Choi   +8 more
doaj   +1 more source

Monitoring of veterinary drug residues in livestock products with antimicrobial resistance

Applied Biological Chemistry
Antimicrobial resistance (AMR) in animal-derived products remains a global concern, while reports on veterinary drug (VD) residues in such products are relatively rare.
Dahae Park, Yu Ra Kim, Ji Young Kim, Jang-Duck Choi, Guiim Moon, Dong Woo Shin   +5 more
doaj   +1 more source

Simultaneous determination of 31 Sulfonamide residues in various livestock matrices using liquid chromatography-tandem mass spectrometry

Applied Biological Chemistry
The widespread use of sulfonamides can result in the residue of sulfonamides in the foods of animal origin that are the major concerns of consumers and regulatory bodies due to their adverse reaction such as the development of antibiotic resistance.
Yu Ra Kim, Sunyoung Park, Ji Young Kim, Jang-Duck Choi, Gui-Im Moon   +4 more
doaj   +1 more source

Papyrus: a large-scale curated dataset aimed at bioactivity predictions

Journal of Cheminformatics, 2023
With the ongoing rapid growth of publicly available ligand–protein bioactivity data, there is a trove of valuable data that can be used to train a plethora of machine-learning algorithms.
O. J. M. Béquignon, B. J. Bongers, W. Jespers, A. P. IJzerman, B. van der Water, G. J. P. van Westen   +5 more
doaj   +1 more source

Risk Perception and Drug Safety Evaluation [PDF]

, 1991
The authors present a Risk communication framework based on a survey of empirical research concerning public Risk perceptions.
Vertinsky, Ilan B., Wehrung, Donald A.
core   +1 more source

Optimization of an LC–MS/MS analytical method for strychnine in livestock and fishery products

Applied Biological Chemistry
Strychnine, an alkaloid recognized for its antagonist effects on glycine and acetylcholine receptors, is highly toxic and banned in several countries. It is also set to restricted in Republic of Korea from 2024, creating a need for a quantitative test ...
Jin Ha Sim, Hyesu Lee, Ji Young Kim, So–Ra Park, Gui–Hyun Jang, Miok Eom   +5 more
doaj   +1 more source

Arrests for Drug Offenses in Alaska: 2000-2011 [PDF]

, 2013
This fact sheet presents data on arrests for drug offenses made by Alaska police agencies for the period 2000 through 2011. The report presents drug offense arrest information for both adults and juveniles for the 12-year period, including number of drug
Myrstol, Brad A.
core