Results 11 to 20 of about 43,453 (280)

Revisiting the isobole and related quantitative methods for assessing drug synergism. [PDF]

J Pharmacol Exp Ther, 2012
Tallarida RJ.
europepmc   +3 more sources

Evaluation the combination of chlorpheniramine and tramadol at a level of thermal and visceral antinociceptive in a mouse acute pain model [PDF]

Iraqi Journal of Veterinary Sciences, 2023
The possible benefits of employing combination treatment include the ability to increase antinociceptive effects while minimizing the occurrence of unfavorable side effects.
Ali I. Thannon, Gada A. Faris
doaj   +1 more source

The synergism between alcohols and other drugs

The Journal of Physiology, 1927
L. M. Pickford
openalex   +5 more sources

In vitro and in vivo antimicrobial activity of an active plant-based quadrocomplex for skin hygiene [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2022
Context: The current epidemiological situation causes a new surge of interest to perspective antimicrobial formulations for proper skin hygiene. Aims: To evaluate in vitro and in vivo the antimicrobial activity of a novel active quadrocomplex (QC) for
Viktor A. Filatov, Olesya Yu. Kulyak, Elena I. Kalenikova   +2 more
doaj   +1 more source

Pharmacodynamic target attainment of the synergism of ceftazidime-avibactam in combination with amikacin against OXA-producing extensively drug-resistant or pan drug-resistant (XDR/PDR) Pseudomonas aeruginosa. [PDF]

Eur J Clin Microbiol Infect Dis
Kang Y, Cui J.
europepmc   +2 more sources

Synergistic anti-cancer effects of silibinin-etoposide combination against human breast carcinoma MCF-7 and MDA-MB-231 cell lines [PDF]

Iranian Journal of Basic Medical Sciences, 2021
Objective(s): Recently, there is a significant focus on combination chemotherapy for cancer using a cytotoxic drug and a phytochemical compound. We investigated the effect of silibinin on etoposide-induced apoptosis in MCF-7 and MDA-MB-231 breast ...
Mahdie Koushki, Azam Khedri, Mohammad Aberomand, Kourosh Akbari Baghbani, Ghorban Mohammadzadeh   +4 more
doaj   +1 more source

Synergistic Interaction and Binding Efficiency of Tetracaine Hydrochloride (Anesthetic Drug) with Anionic Surfactants in the Presence of NaCl Solution Using Surface Tension and UV–Visible Spectroscopic Methods

Gels, 2022
Surfactants are ubiquitous materials that are used in diverse formulations of various products. For instance, they improve the formulation of gel by improving its wetting and rheological properties. Here, we describe the effects of anionic surfactants on
Naved Azum, Malik Abdul Rub, Anish Khan, Maha M. Alotaibi, Abdullah M. Asiri   +4 more
doaj   +1 more source

Dichloroacetate and PX-478 exhibit strong synergistic effects in a various number of cancer cell lines

BMC Cancer, 2021
Background One key approach for anticancer therapy is drug combination. Drug combinations can help reduce doses and thereby decrease side effects. Furthermore, the likelihood of drug resistance is reduced.
Jonas Parczyk, Jérôme Ruhnau, Carsten Pelz, Max Schilling, Hao Wu, Nicole Nadine Piaskowski, Britta Eickholt, Hartmut Kühn, Kerstin Danker, Andreas Klein   +9 more
doaj   +1 more source

Combination of Conventional Drugs with Biocompounds Derived from Cinnamic Acid: A Promising Option for Breast Cancer Therapy

Biomedicines, 2023
Despite the options available for breast cancer (BC) therapy, several adverse effects and resistance limit the success of the treatment. Furthermore, the use of a single drug is associated with a high failure rate.
Lyvia Eloiza de Freitas Meirelles, Maria Vitória Felipe de Souza, Lucimara Rodrigues Carobeli, Fabrício Morelli, Natália Lourenço Mari, Edilson Damke, Cristiane Suemi Shinobu Mesquita, Jorge Juarez Vieira Teixeira, Marcia Edilaine Lopes Consolaro, Vânia Ramos Sela da Silva   +9 more
doaj   +1 more source

Drug Combinations: A New Strategy to Extend Drug Repurposing and Epithelial-Mesenchymal Transition in Breast and Colon Cancer Cells

Biomolecules, 2022
Despite the progressive research and recent advances in drug therapy to treat solid tumours, the number of cases and deaths in patients with cancer is still a major health problem.
Diana Duarte, Alexandra Rêma, Irina Amorim, Nuno Vale   +3 more
doaj   +1 more source