Results 31 to 40 of about 12,752,015 (316)
Antitumor Drugs and Their Targets [PDF]
Molecules, 2020 Through novel methodologies, including both basic and clinical research, progress has been made in the therapy of solid cancer. Recent innovations in anticancer therapies, including immune checkpoint inhibitor biologics, therapeutic vaccines, small drugs, and CAR-T cell injections, mark a new epoch in cancer research, already known for faster (epi ...
openaire +4 more sources
Drugs and Targets in Fibrosis [PDF]
Frontiers in Pharmacology, 2017 Fibrosis contributes to the development of many diseases and many target molecules are involved in fibrosis. Currently, the majority of fibrosis treatment strategies are limited to specific diseases or organs. However, accumulating evidence demonstrates great similarities among fibroproliferative diseases, and more and more drugs are proved to be ...
Xiaoyi Li +5 more
openaire +3 more sources
Asian Journal of Pharmaceutical Sciences, 2019 To achieve targeted thrombolysis, a targeted delivery system of lumbrokinase (LK) was constructed using RGDfk-conjugated hybrid micelles. Based on the specific affinity of RGDfk to glycoprotein complex of GPⅡb/Ⅲa expressed on the surface of membrane of ...
Yang Pan, Xiahui Wang, Zongning Yin
doaj +1 more source
Nano-Drug Delivery Systems in Oral Cancer Therapy: Recent Developments and Prospective
, 2023 Oral cancer (OC), characterized by malignant tumors in the mouth, is one of the most prevalent malignancies worldwide. Chemotherapy is a commonly used treatment for OC; however, it often leads to severe side effects on human bodies.
Zhiyong Li +9 more
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Nature Communications, 2017 Mesangial cell-mediated glomerulonephritis is a frequent cause of kidney disease. Here the authors show that celastrol loaded in albumin nanoparticles efficiently targets mesangial cells, and is effective in rat models.
Ling Guo +8 more
doaj +1 more source
Recent Progress in Gas Sensors Based on P3HT Polymer Field-Effect Transistors
Sensors, 2023 In recent decades, the rapid development of the global economy has led to a substantial increase in energy consumption, subsequently resulting in the emission of a significant quantity of toxic gases into the environment.
Si Cheng +5 more
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Magnetic aerosol drug targeting in lung cancer therapy using permanent magnet
Drug Delivery, 2019 Primary bronchial cancer accounts for almost 20% of all cancer death worldwide. One of the emerging techniques with tremendous power for lung cancer therapy is magnetic aerosol drug targeting (MADT).
M. D. Manshadi +6 more
semanticscholar +1 more source
Targeting Strategies for Tissue-Specific Drug Delivery.
Cell, 2020 Off-target effects of systemically administered drugs have been a major hurdle in designing therapies with desired efficacy and acceptable toxicity.
Zong-Min Zhao +3 more
semanticscholar +1 more source
Bisphosphonate conjugation for bone specific drug targeting
Bone Reports, 2018 Bones provide essential functions and are sites of unique biochemistry and specialized cells, but can also be sites of disease. The treatment of bone disorders and neoplasia has presented difficulties in the past, and improved delivery of drugs to bone ...
Kristen Farrell +3 more
semanticscholar +1 more source
Implantable sandwich PHBHHx film for burst-free controlled delivery of thymopentin peptide
Acta Pharmaceutica Sinica B, 2018 Sustained release and non-parental formulations of peptides and protein drugs are highly desirable because of enhanced therapeutic effects as well as improved patient compliance. This is especially true for small peptides such as thymopentin (TP5).
Ke Peng +5 more
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