Results 91 to 100 of about 2,667,430 (358)

Combination drug therapy for hyperlipidemia [PDF]

open access: yesClinical Cardiology, 2009
Low-dose combination hypolipidemic therapy may be the best approach to achieve the stringent target low-density lipoprotein cholesterol (LDL-C) levels recominended by the latest National Cholesterol Education Program guidelines in patients with multiple risk factors or existing coronary heart disease. Three randomized, double-blind clinical trials have
openaire   +2 more sources

Combination of tocainide and quinidine for better tolerance and additive effects in patients with coronary artery disease [PDF]

open access: yes, 1987
The efficacy and tolerance of tocainide used alone and in combination with quinidine were studied in 20 patients with coronary artery disease and frequent (≥30/h) ventricular premature complexes.
Fisher, John D.   +2 more
core   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Drug‑Drug and Drug‑Nutraceutical Cocrystal/Salt as Alternative Medicine for Combination Therapy: A Crystal Engineering Approach

open access: yes, 2018
The pre-formulation of pharmaceutical cocrystals and salts is a concept of crystal engineering that has emerged as a promising technique for drug development in pharmaceutical industry.
Ranjit Thakuria, B. Sarma
semanticscholar   +1 more source

Exploiting the synergy between carboplatin and ABT-737 in the treatment of ovarian carcinomas [PDF]

open access: yes, 2012
Platinum drug-resistance in ovarian cancers is a major factor contributing to chemotherapeutic resistance of recurrent disease. Members of the Bcl-2 family such as the anti-apoptotic protein Bcl-XL have been shown to play a role in this resistance ...
Byrne, H. M.   +3 more
core  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Trigeminal neuralgia: successful antiepileptic drug combination therapy in three refractory cases

open access: yesDrug, Healthcare and Patient Safety, 2011
Lara Prisco1, Mario Ganau2, Federica Bigotto1, Francesca Zornada11Department of Anaesthesiology, Intensive Care and Emergency Medicine, University Hospital of Cattinara, 2Graduate School of Nanotechnology, University of Trieste, ItalyAbstract ...
Prisco L, Ganau M, Bigotto F, Zornada F
doaj  

Modeling antibiotic treatment in hospitals: A systematic approach shows benefits of combination therapy over cycling, mixing, and mono-drug therapies

open access: yesPLoS Comput. Biol., 2017
Multiple treatment strategies are available for empiric antibiotic therapy in hospitals, but neither clinical studies nor theoretical investigations have yielded a clear picture when which strategy is optimal and why. Extending earlier work of others and
Burcu Tepekule   +4 more
semanticscholar   +1 more source

Management of intestinal transplantation in humans [PDF]

open access: yes, 1992
We report here the clinical experience and management guidelines for the nine consecutive cases who received either an isolated small intestinal graft (n = 1) or an intestine liver combination at the University of Pittsburgh, with FK 506 being the basic ...
Abu-Elmagd, K   +14 more
core  

Analysis of prescription pattern of antihypertensive medication and adherence to Beers criteria in geriatric department of a tertiary care hospital in Mysuru [PDF]

open access: yes, 2019
Background: The objective of the present study was to evaluate the prescription pattern of anti-hypertensive drugs and adherence to Beers’ criteria in geriatric department of JSS Hospital, Mysuru.Methods: An observational, prospective, cross-sectional ...
K., Jayanthi M.   +3 more
core   +2 more sources

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