Results 71 to 80 of about 2,849,098 (354)
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Combination Drug Therapy for Benign Prostatic Hyperplasia (BPH)
Background: The incidence of benign prostatic hyperplasia peaks 80% in old age. Bothersome symptoms and progression to acute urinary retention and need for surgery are important concerns.
Oliech J.S.
doaj
Cancer chemotherapy suffers from drug resistance and side effects of the drugs. Combination therapies have been attracted attention to overcome these limitations of traditional cancer treatments.
Bilgi Kip, Cansu Umran Tunc, Omer Aydin
doaj +1 more source
In silico drug combination discovery for personalized cancer therapy
BackgroundDrug combination therapy, which is considered as an alternative to single drug therapy, can potentially reduce resistance and toxicity, and have synergistic efficacy. As drug combination therapies are widely used in the clinic for hypertension,
Minji Jeon +4 more
semanticscholar +1 more source
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman +8 more
wiley +1 more source
Antiarrhythmic drug combination therapy.
Enhanced antiarrhythmic ef~cacy may be achieved using a number of theoretic strategies. First, a drug that prolongs “time to ~rst recurrence” of a symptomatic arrhythmia could be combined with a second drug that changes the character of the recurrent arrhythmia from a hemodynamically compromising episode to one that produces few symptoms and no ...
openaire +3 more sources
Trigeminal neuralgia: successful antiepileptic drug combination therapy in three refractory cases
Lara Prisco1, Mario Ganau2, Federica Bigotto1, Francesca Zornada11Department of Anaesthesiology, Intensive Care and Emergency Medicine, University Hospital of Cattinara, 2Graduate School of Nanotechnology, University of Trieste, ItalyAbstract ...
Prisco L, Ganau M, Bigotto F, Zornada F
doaj
Management of intestinal transplantation in humans [PDF]
We report here the clinical experience and management guidelines for the nine consecutive cases who received either an isolated small intestinal graft (n = 1) or an intestine liver combination at the University of Pittsburgh, with FK 506 being the basic ...
Abu-Elmagd, K +14 more
core
Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma [PDF]
Intratumoral heterogeneity of signaling networks may contribute to targeted cancer therapy resistance, including in the highly lethal brain cancer glioblastoma (GBM).
Bonetti, Bruno +23 more
core +1 more source
Sensitization of Drug Resistant Cancer Cells: A Matter of Combination Therapy
Cancer drug resistance is an enormous problem. It is responsible for most relapses in cancer patients following apparent remission after successful therapy.
M. Leary +3 more
semanticscholar +1 more source

