Results 11 to 20 of about 22,360 (228)

Multimodal Imaging and En Face OCT Detection of Calcified Drusen in Eyes with Age-Related Macular Degeneration

Ophthalmology Science, 2022
Purpose: En face OCT imaging was investigated as a method for the detection and monitoring of calcified drusen in eyes with nonexudative age-related macular degeneration (AMD). Design: Retrospective case series of a prospective study.
Jeremy Liu, BS, Rita Laiginhas, MD, Mengxi Shen, MD, Yingying Shi, MD, Jianqing Li, MD, Omer Trivizki, MD, Nadia K. Waheed, MD, Giovanni Gregori, PhD, Philip J. Rosenfeld, MD, PhD   +8 more
doaj   +2 more sources

Patients with MPNs and retinal drusen show signs of complement system dysregulation and a high degree of chronic low-grade inflammation

EClinicalMedicine, 2022
Summary: Background: The hematopoietic stem cell disorders, myeloproliferative neoplasms (MPNs), are characterised by chronic low-grade inflammation (CLI).
Charlotte Liisborg, Vibe Skov, Lasse Kjær, Hans Carl Hasselbalch, Torben Lykke Sørensen   +4 more
doaj   +2 more sources

Drusen-specific dark adaptation profiles in intermediate age-related macular degeneration [PDF]

International Journal of Retina and Vitreous
Aims To investigate the influence of macular drusen phenotypes on dark adaptation (DA) in intermediate age-related macular degeneration (iAMD). Methods This cross-sectional, multicentric study enrolled 57 eyes of 43 iAMD patients.
Paolo Forte, Lorenzo Ferro Desideri, Marco Nassisi, Federica Milanesi, Alessandro Feo, Irene Bagnasco, Sharlot M. Iglesia, Giovanni Forte, Davide Scandella, Fabiola Roccatagliata, Vincenzo Fontana, Chiara Maria Eandi, Michele Iester, Jasleen K. Jolly, Martin S. Zinkernagel, Francesco Viola, Massimo Nicolò   +16 more
doaj   +2 more sources

Choriocapillaris Flow and Retinal Vascular Fractal Dimension in Dry Age-Related Macular Degeneration [PDF]

Diagnostics
Background/Objective: To evaluate the association between optical coherence tomography angiography (OCTA)-derived choriocapillaris flow (CCflow), retinal vascular fractal dimension (FD), and drusen burden in eyes with dry age-related macular degeneration
Mine Ozturk, Abdullah Ağın
doaj   +2 more sources

Multimodal imaging for early drusen detection: RM-SLO as a promising imaging approach [PDF]

Frontiers in Medicine
PurposeThis study aimed to evaluate the diagnostic performance of retro-mode scanning laser ophthalmoscopy (RM-SLO) in detecting drusen compared to conventional multimodal imaging.
Shujun Zhang, Xiaoling Zhang, Zixun Wang, Wei Shi, Zhaoyang Ren, Yanna Wang, Qian Jia, Yongchao Li, Yali Guo, Zhiqing Li   +9 more
doaj   +2 more sources

A Deep Learning Framework for the Detection and Quantification of Reticular Pseudodrusen and Drusen on Optical Coherence Tomography [PDF]

Translational Vision Science & Technology, 2022
Purpose The purpose of this study was to develop and validate a deep learning (DL) framework for the detection and quantification of reticular pseudodrusen (RPD) and drusen on optical coherence tomography (OCT) scans. Methods A DL framework was developed
R. Schwartz, Hagar Khalid, S. Liakopoulos, Y. Ouyang, Coen de Vente, C. González-Gonzalo, Aaron Y. Lee, R. Guymer, E. Chew, C. Egan, Zhichao Wu, Himeesh Kumar, Joseph Farrington, C. S'anchez, A. Tufail   +14 more
semanticscholar   +1 more source

Point-to-point associations of drusen and hyperreflective foci volumes with retinal sensitivity in non-exudative age-related macular degeneration

Eye, 2023
Objectives To evaluate the quantitative impact of drusen and hyperreflective foci (HRF) volumes on mesopic retinal sensitivity in non-exudative age-related macular degeneration (AMD).
G. Reiter, Hrvoje Bogunović, F. Schlanitz, Wolf-Dieter Vogl, Philipp Seeböck, Dariga Ramazanova, U. Schmidt-Erfurth   +6 more
semanticscholar   +1 more source

Automated segmentation and quantification of calcified drusen in 3D swept source OCT imaging.

Biomedical Optics Express, 2023
Qualitative and quantitative assessments of calcified drusen are clinically important for determining the risk of disease progression in age-related macular degeneration (AMD).
Jie Lu, Yuxuan Cheng, Jianqing Li, Ziyu Liu, Mengxi Shen, Qinqin Zhang, Jeremy Liu, Gissel Herrera, Farhan E. Hiya, Rosalyn Morin, Joan Joseph, Giovanni Gregori, P. Rosenfeld, Ruikang K Wang   +13 more
semanticscholar   +1 more source

Histology, dimensions, and fluorescein staining characteristics of nodular and cuticular drusen in age-related macular degeneration

Retina, 2023
Supplemental Digital Content is Available in the Text. Base widths were determined for isolated nodular drusen in donor eyes and two eyes with fluorescein angiography during life, including “starry sky” cuticular drusen.
C. Evers, Ling Chen, J. Messinger, M. Killingsworth, K. Freund, C. Curcio   +5 more
semanticscholar   +1 more source

Relationship Between Drusen Height and OCT Biomarkers of Atrophy in Non-Neovascular AMD

Investigative Ophthalmology and Visual Science, 2022
Purpose To determine if increasing drusen height correlates with predictive optical coherence tomography (OCT) biomarkers of atrophy. Methods Retrospective cross-sectional study that enrolled patients with drusen associated with intermediate AMD. Macular
A. Au, Ahmad Santina, Neda Abraham, Miri Fogel Levin, Giulia Corradetti, S. Sadda, D. Sarraf   +6 more
semanticscholar   +1 more source