Results 21 to 30 of about 15,961 (225)

Increased retinal drusen in IgA glomerulonephritis are further evidence for complement activation in disease pathogenesis

Scientific Reports, 2022
Drusen are retinal deposits comprising cell debris, immune material and complement that are characteristic of macular degeneration but also found in glomerulonephritis.
P. Harraka, Tony Wightman, Sarah Akom, Kieran Sandhu, Deb Colville, Andrew Catran, David Langsford, Timothy Pianta, David Barit, Frank Ierino, Alison Skene, Heather Mack, Judy Savige   +12 more
doaj   +1 more source

Clinical Characteristics of Neovascular Age-Related Macular Degeneration without Typical Drusen

Journal of Ophthalmology, 2021
Purpose. To evaluate the clinical characteristics of neovascular age-related macular degeneration (nAMD) patients without typical drusen. Methods. We retrospectively studied 165 eyes in 165 patients with treatment-naïve nAMD, including typical AMD and ...
Hiroyuki Kamao, Katsutoshi Goto, Kento Matsuno, Kenichi Mizukawa, Atsushi Miki, Junichi Kiryu   +5 more
doaj   +1 more source

Multispectral pattern recognition measures change in drusen area in age-related macular degeneration with high congruency to expert graders

Scientific Reports, 2022
Drusen are a hallmark lesion of age-related macular degeneration (AMD) and changes in their area and/or volume are strongly associated with disease progression. Assessment of longitudinal change in drusen size in clinical practice however is limited to a
Judy Nam, Angelica Ly, Michael Kalloniatis, Lisa Nivison-Smith   +3 more
doaj   +1 more source

Comparison of Drusen Volume Assessed by Two Different OCT Devices. [PDF]

, 2020
To compare drusen volume between Heidelberg Spectral Domain (SD-) and Zeiss Swept-Source (SS) PlexElite Optical Coherence Tomography (OCT) determined by manual and automated segmentation methods.
Stefanos Apostolopoulos, Martin S. Zinkernagel, Marco Beck, Mosinska, Agata, Devika S. Joshi, Apostolopoulos, Stefanos, Sandro De Zanet, Agata Mosinska, Andreas Ebneter, Lieselotte Berger, Zinkernagel, Martin S., Gerd Klose, Sebastian Wolf, Joshi, Devika S, Berger, Lieselotte, Munk, Marion R., Beck, Marco, Klose, Gerd, Marion R. Munk, De Zanet, Sandro, Ebneter, Andreas, Wolf, Sebastian   +21 more
core   +1 more source

Dry Age-Related Macular Degeneration – A New Approach In Optical Coherence Tomography Monitoring And Quantitative Assessment [PDF]

Journal of Biomedical & Clinical Research, 2014
The purpose of the study was to present the ability of Drusen analysis software tool to measure drusen area and volume in patients with dry age-related macular degeneration (AMD).
Elitsa Hristova, Zornitsa Zlatarova
doaj   +3 more sources

Multimodal Imaging and En Face OCT Detection of Calcified Drusen in Eyes with Age-Related Macular Degeneration

Ophthalmology Science, 2022
Purpose: En face OCT imaging was investigated as a method for the detection and monitoring of calcified drusen in eyes with nonexudative age-related macular degeneration (AMD). Design: Retrospective case series of a prospective study.
Jeremy Liu, BS, Rita Laiginhas, MD, Mengxi Shen, MD, Yingying Shi, MD, Jianqing Li, MD, Omer Trivizki, MD, Nadia K. Waheed, MD, Giovanni Gregori, PhD, Philip J. Rosenfeld, MD, PhD   +8 more
doaj   +1 more source

Retinal drusen in glomerulonephritis with or without immune deposits suggest systemic complement activation in disease pathogenesis

Scientific Reports, 2022
Retinal drusen are characteristic of macular degeneration and complement activation, but also occur in C3, lupus and IgA nephropathy. This cross-sectional observational study compared drusen counts in different forms of glomerulonephritis.
P. Harraka, H. Mack, D. Colville, D. Barit, D. Langsford, T. Pianta, F. Ierino, Judy Savige   +7 more
doaj   +1 more source

Ex Vivo Hyperspectral Autofluorescence Imaging and Localization of Fluorophores in Human Eyes with Age-Related Macular Degeneration

Vision, 2018
To characterize fluorophore signals from drusen and retinal pigment epithelium (RPE) and their changes in age related macular degeneration (AMD), the authors describe advances in ex vivo hyperspectral autofluorescence (AF) imaging of human eye tissue ...
Taariq Mohammed, Yuehong Tong, Julia Agee, Nayanika Challa, Rainer Heintzmann, Martin Hammer, Christine A. Curcio, Thomas Ach, Zsolt Ablonczy, R. Theodore Smith   +9 more
doaj   +1 more source

Macular neovascularization in eyes with pachydrusen

Scientific Reports, 2021
The natural history and clinical significance of pachydrusen is unclear. This study aims to compare the longitudinal changes of eyes with pachydrusen and soft drusen and progression to exudative macular neovascularisation (MNV). Patients with a diagnosis
Kelvin Yi Chong Teo, Kai Xiong Cheong, Ricardo Ong, Haslina Hamzah, Yasuo Yanagi, Tien Yin Wong, Usha Chakravarthy, Chui Ming Gemmy Cheung   +7 more
doaj   +1 more source

Exploration of cuticular drusen: comprehensive analysis from multi-modal imaging characteristics to clinical diagnosis and treatment

Yanke Xuebao
With the application of multimodal imaging techniques, a specific subtype of age-related macular degeneration (AMD), known as cuticular drusen, has been identified.
ZHANG Guanghan, ZHANG Xiongze, JI Yuying
doaj   +1 more source