Results 31 to 40 of about 22,360 (228)

OCT Based Interpretation of the Optic Nerve Head Anatomy and Prevalence of Optic Disc Drusen in Patients with Idiopathic Intracranial Hypertension (IIH)

Life, 2021
We aimed to systematically examine the optic nerve head anatomy in patients with idiopathic intracranial hypertension (IIH) using a standardized optical coherence tomography (OCT) protocol.
E. Wibroe, L. Malmqvist, S. Hamann
semanticscholar   +1 more source

Increased retinal drusen in IgA glomerulonephritis are further evidence for complement activation in disease pathogenesis

Scientific Reports, 2022
Drusen are retinal deposits comprising cell debris, immune material and complement that are characteristic of macular degeneration but also found in glomerulonephritis.
P. Harraka, Tony Wightman, Sarah Akom, Kieran Sandhu, Deb Colville, Andrew Catran, David Langsford, Timothy Pianta, David Barit, Frank Ierino, Alison Skene, Heather Mack, Judy Savige   +12 more
doaj   +1 more source

Clinical Characteristics of Neovascular Age-Related Macular Degeneration without Typical Drusen

Journal of Ophthalmology, 2021
Purpose. To evaluate the clinical characteristics of neovascular age-related macular degeneration (nAMD) patients without typical drusen. Methods. We retrospectively studied 165 eyes in 165 patients with treatment-naïve nAMD, including typical AMD and ...
Hiroyuki Kamao, Katsutoshi Goto, Kento Matsuno, Kenichi Mizukawa, Atsushi Miki, Junichi Kiryu   +5 more
doaj   +1 more source

A New Method for Visualizing Drusen and Their Progression in Flood-Illumination Adaptive Optics Ophthalmoscopy

Translational Vision Science & Technology, 2021
Purpose Drusen are dynamic sub-RPE deposits that are risk factors for late-stage age-related macular degeneration (AMD). Here we show a new imaging method using flood-illumination adaptive optics (FIAO) that reveal drusen with high contrast and ...
E. Rossi, N. Norberg, C. Eandi, Céline Chaumette, S. Kapoor, Laura Le, V. Snyder, J. Martel, J. Gautier, K. Gocho, K. Dansingani, J. Chhablani, Angelo Arleo, S. Mrejen, J. Sahel, K. Grieve, M. Pâques   +16 more
semanticscholar   +1 more source

Multispectral pattern recognition measures change in drusen area in age-related macular degeneration with high congruency to expert graders

Scientific Reports, 2022
Drusen are a hallmark lesion of age-related macular degeneration (AMD) and changes in their area and/or volume are strongly associated with disease progression. Assessment of longitudinal change in drusen size in clinical practice however is limited to a
Judy Nam, Angelica Ly, Michael Kalloniatis, Lisa Nivison-Smith   +3 more
doaj   +1 more source

Dry Age-Related Macular Degeneration – A New Approach In Optical Coherence Tomography Monitoring And Quantitative Assessment [PDF]

Journal of Biomedical & Clinical Research, 2014
The purpose of the study was to present the ability of Drusen analysis software tool to measure drusen area and volume in patients with dry age-related macular degeneration (AMD).
Elitsa Hristova, Zornitsa Zlatarova
doaj   +3 more sources

Evaluating the Occurrence of Rare Variants in the Complement Factor H Gene in Patients With Early-Onset Drusen Maculopathy

JAMA ophthalmology, 2021
Key Points Question What are the genotypic and phenotypic characteristics of patients with early-onset drusen maculopathy? Findings In this case-control study, patients with early-onset drusen maculopathy were frequently carriers of rare genetic variants
Anita de Breuk, T. Heesterbeek, Bjorn Bakker, T. Verzijden, Y. Lechanteur, C. Klaver, A. D. den Hollander, C. Hoyng   +7 more
semanticscholar   +1 more source

Ex Vivo Hyperspectral Autofluorescence Imaging and Localization of Fluorophores in Human Eyes with Age-Related Macular Degeneration

Vision, 2018
To characterize fluorophore signals from drusen and retinal pigment epithelium (RPE) and their changes in age related macular degeneration (AMD), the authors describe advances in ex vivo hyperspectral autofluorescence (AF) imaging of human eye tissue ...
Taariq Mohammed, Yuehong Tong, Julia Agee, Nayanika Challa, Rainer Heintzmann, Martin Hammer, Christine A. Curcio, Thomas Ach, Zsolt Ablonczy, R. Theodore Smith   +9 more
doaj   +1 more source

Retinal drusen in glomerulonephritis with or without immune deposits suggest systemic complement activation in disease pathogenesis

Scientific Reports, 2022
Retinal drusen are characteristic of macular degeneration and complement activation, but also occur in C3, lupus and IgA nephropathy. This cross-sectional observational study compared drusen counts in different forms of glomerulonephritis.
P. Harraka, H. Mack, D. Colville, D. Barit, D. Langsford, T. Pianta, F. Ierino, Judy Savige   +7 more
doaj   +1 more source

Macular neovascularization in eyes with pachydrusen

Scientific Reports, 2021
The natural history and clinical significance of pachydrusen is unclear. This study aims to compare the longitudinal changes of eyes with pachydrusen and soft drusen and progression to exudative macular neovascularisation (MNV). Patients with a diagnosis
Kelvin Yi Chong Teo, Kai Xiong Cheong, Ricardo Ong, Haslina Hamzah, Yasuo Yanagi, Tien Yin Wong, Usha Chakravarthy, Chui Ming Gemmy Cheung   +7 more
doaj   +1 more source