Results 91 to 100 of about 17,907 (178)

Humanin Mitigates Aβ‐Induced Retinal Pigment Epithelium Injury via AMPK‐Beclin1‐Dependent Mitophagy

Aging Cell, Volume 25, Issue 7, July 2026.
Humanin (HN) enhanced the clearance of Aβ‐accumulated mitochondria in the RPE while preserving retinal function and RPE barrier integrity. HN activated AMP‐activated protein kinase (AMPK), leading to phosphorylation of ULK1 and Beclin1, which promoted the interaction between Beclin1 and Parkin and their translocation to mitochondria.
Ha Young Jang, Suyeon Choi, Soo‐Jin Kim, Sooyun Kim, Dong Hyun Jo, Tae Geol Lee, Kyu‐Sang Park, Jeong Hun Kim   +7 more
wiley   +1 more source

Engineering Extracellular Vesicles for Anti‐Aging Therapy: Mechanisms, Applications, and Perspectives

Aging Cell, Volume 25, Issue 7, July 2026.
This review systematically elucidates the multifactorial anti‐aging mechanisms of extracellular vesicles (EVs). By bridging fundamental biology with advanced bioengineering, scalable manufacturing, and clinical translation, it establishes a comprehensive framework for developing next‐generation EVs‐based precision nanotherapeutics to combat systemic ...
Xian Huang, Qiujie Li, Guofang Tao, Xulin Gan, Jiangjie Lu, Sergei Krasny, Liyun Shi   +6 more
wiley   +1 more source

Choriocapillaris changes in dry age-related macular degeneration and geographic atrophy: a review

Eye and Vision, 2018
Age-related macular degeneration (AMD) is a leading cause of central vision loss worldwide. The progression of dry AMD from early to intermediate stages is primarily characterized by increasing drusen formation and adverse impact on outer retinal cells ...
Malvika Arya, Almyr S. Sabrosa, Jay S. Duker, Nadia K. Waheed   +3 more
doaj   +1 more source

Functional Visual Outcomes of Wearing Colored Filters in Patients with Dry Age-Related Macular Degeneration

Journal of Shalamar Medical & Dental College
Background: Age-related macular degeneration (AMD) leads to a permanent decrease in vision, thus affecting the quality of life. Any intervention or modality that enhances the quality of vision and, in turn, quality of life is vital.
Syeda Baneen Jannat, Muhammad Shaheer, Asima Rafique   +2 more
doaj   +1 more source

Treatments for dry age-related macular degeneration and Stargardt disease: a systematic review

Health Technology Assessment, 2018
Background: Age-related macular degeneration (AMD) is the leading cause of visual loss in older people. Advanced AMD takes two forms, neovascular (wet) and atrophic (dry).
Norman Waugh, Emma Loveman, Jill Colquitt, Pamela Royle, Jian Lee Yeong, Geraldine Hoad, Noemi Lois   +6 more
doaj   +1 more source

Bidirectional causal associations between immune cell phenotypes and age-related macular degeneration subtypes: A mendelian randomization study

Experimental Gerontology
Background: Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the elderly population, characterized by two primary subtypes: dry AMD (dAMD) and wet AMD (wAMD).
Zihao Zhuang, Xinyu Jia, Haixia Lin, Pengcheng Hu, Jianmin Hu   +4 more
doaj   +1 more source

<i>Fructus lycii</i> mitigates oxidative stress in dry age-related macular degeneration models <i>via</i> Nrf2/ARE pathway. [PDF]

Int J Ophthalmol
Peng Y, Liang LY, Wei HL, Huang Q, Yuan LM, Xie YY, Tang QY, Wang AQ, Li JM, Guo QS, Huang BL.   +10 more
europepmc   +1 more source

LONG-TERM EFFICACY AND SAFETY OF PHOTOBIOMODULATION IN DRY AGE-RELATED MACULAR DEGENERATION (LIGHTSITE III: 24-MONTH ANALYSIS). [PDF]

Retina
Jaffe GJ, Boyer D, Hu A, Warrow D, Xavier S, Gonzalez V, Lad E, Rosen RB, Do DV, Schneiderman T, Ho AC, Munk MR, Tedford SE, Croissant CL, Rückert R, Lavin PT, Tedford CE.   +16 more
europepmc   +1 more source

Dry Age-Related Macular Degeneration [PDF]

, 2016
openaire   +1 more source

Letter to the Editor Regarding "Multiwavelength Photobiomodulation Improves Multiple Aspects of Visual Function in Early-Stage Dry Age-Related Macular Degeneration". [PDF]

Ophthalmol Ther
Karakosta C, MacLaren RE.
europepmc   +1 more source