Results 31 to 40 of about 3,393 (249)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Optimized wood drying

, 2000
Nonlinear programming methods are used to create effective drying schedules for boards. A two-dimensional. orthotropic drying model is connected to an optimization routine that solves convex sub-problems. The iterative optimi7ation program calculates the
Arfvidsson, J, Carlsson, Peter,
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Evaluation of a Moisture Diffusion Model for Analyzing the Convective Drying Kinetics of Lavandula x allardii Leaves

Computation, 2021
In the present case study, a moisture diffusion model is developed to simulate the drying kinetics of Lavandula x allardii leaves for non-stationary convective drying regimes.
Vasileios Chasiotis, Dimitrios Tzempelikos, Andronikos Filios   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

DEVELOPMENT OF DRYING SCHEDULES FOR RUBBER AND PINE TIMBER FOR THE DEHUMIDIFICATION KILN DRYING

, 2013
Most of the limber in Sri Lanka is used in unseasoned state or seasoned using conventionalkilns which use fuel wood boilers or open fires as a heating source. A study has beenconducted to introduce dehumidification drying kiln. which is easy to fabricate
H. S. Amarasekera, R. S. Sujith Rathnayake, Rathnayake, R. S. Sujith, Amarasekera, H. S.   +3 more
core   +1 more source

Evaluation the effect of kiln schedule on warp and surface checking in beech (fagus orientalis Lipsky) at 5 cm thickness [PDF]

تحقیقات علوم چوب و کاغذ ایران, 2011
In this research , beech (fagus orientalis Lipsky ) lumbers at 5 cm thickness wereran domically selected and commercially cut down from sari region(Neka choobcompany) ,with three schedule namely T5-C3, T5-C4, T6-C4 were adapted fordrying the lumbers down
Yadolah Hossein poor, Vahid Tazkrrezaei
doaj   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Comparing two intermittent drying schedules for timber drying quality

, 2018
Intermittent drying techniques for drying timber may provide various benefits by improving timber quality and addressing energy efficiency through saving in energy consumption.
Phonetip, K, Belleville, B, Brodie, G, Ozarska, B   +3 more
core   +1 more source

Development of Drying Schedule of Superior and Conventional Teak Wood of Ten Years-old Planted in Blora, Central Java

Jurnal Ilmu Kehutanan, 2016
The aims of this study were to investigate drying defect characteristics, to develop proper drying schedule, and to analyze the relationship between the developed drying schedule and its wood properties.
Tomy Listyanto, Yusuf Setia Darmawan, Rini Pujiarti, Fanny Hidayati, Ganis Lukmandaru, Joko Sulistyo   +5 more
doaj   +1 more source