Results 51 to 60 of about 9,627 (224)

Pemphigus Vulgaris: Application of Occlusal Soft Splint with Topical Steroid in the Treatment

Journal of Indian Academy of Oral Medicine and Radiology, 2011
Pemphigus vulgaris (PV) is a rare autoimmune bullous dermatosis with a high mortality rate if untreated. It is characterized by the binding of IgG autoantibodies to desmogleins 3 (DSG 3), a transmembrane glycoprotein adhesion molecule present on ...
G Vivekanandh Reddy, G Ramlal, K Jitendar Reddy, K Swetha, A Madhavi   +4 more
doaj   +1 more source

Tenapanor Beyond Phosphate: Gut Sodium Transport, Stool Transit Time, and Volume Balance in Dialysis Patients

Hemodialysis International, EarlyView.
ABSTRACT Introduction Tenapanor, a minimally absorbed intestinal NHE3 inhibitor approved for hyperphosphatemia in dialysis, lowers phosphate and reduces intestinal sodium absorption. Its sodium–water signal may have implications beyond phosphate but remains poorly separated from diarrhea‐mediated losses and dialysis prescription artifacts. Methods This
Lucas Maciel de Almeida Corrêa, Luiggi Kevin Virgino Brandão, Clara Belo Gamon Santiago, Alexandre de Assis Barbosa, Gabriel Rian Mazur, Gabriel Costa de Santana, Yan Roberth Delmiro Silva, Letícia Esteves Dante, Ivan Felipe Dutra Júnior   +8 more
wiley   +1 more source

Diosgenin alleviates D-galactose-induced oxidative stress in rats’ brain and liver targeting aging and apoptotic marker genes

Frontiers in Molecular Biosciences
The theory of aging is primarily concerned with oxidative stress caused by an imbalance in reactive oxygen species generation and cellular antioxidants.
Ali H. El-Far, Mona M. Elghaity, Shymaa A. Mohamed, Ahmed E. Noreldin, Yaser H. A. Elewa, Yaser H. A. Elewa, Soad Khalil Al Jaouni, Abdelwahab A. Alsenosy   +7 more
doaj   +1 more source

Modifications of the Transcriptomic Profile of Autoreactive B Cells From Pemphigus Patients After Treatment With Rituximab or a Standard Corticosteroid Regimen

Frontiers in Immunology, 2019
Pemphigus Vulgaris is an autoimmune disease of the skin and mucous membranes, which is due to the production of pathogenic autoantibodies targeting desmoglein (DSG) 1 and 3, which are adhesion proteins of the keratinocytes.
Vivien Hébert, Vivien Hébert, Marie Petit, Maud Maho-Vaillant, Maud Maho-Vaillant, Marie-Laure Golinski, Marie-Laure Golinski, Gaëtan Riou, Céline Derambure, Olivier Boyer, Pascal Joly, Pascal Joly, Sébastien Calbo   +12 more
doaj   +1 more source

Glomerular plasmalemma vesicle‐associated protein‐1 as an endothelial remodelling marker complementing C4d in chronic active antibody‐mediated rejection

Histopathology, EarlyView.
Glomerular plasmalemma vesicle‐associated protein‐1 (PV‐1/PLVAP) identifies dynamic endothelial remodelling in chronic active antibody‐mediated rejection (caABMR), complementing glomerular C4d, which reflects a static footprint of complement activation. Combined assessment of PV‐1 and C4d captures complementary dimensions of microvascular pathology and
Yuto Igarashi, Mayu Shimokawa, Kunio Kawanishi, Toshihito Hirai, Hiroshi Seino, Tomokazu Shimizu, Hideki Ishida, Toshio Takagi   +7 more
wiley   +1 more source

European S2k guidelines on management of autoimmune blistering diseases in children and adolescents

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda, B. Tedbirt, C. Bodemer, M. C. Bolling, M. El Hachem, M. Nikolić, E. Benton, M. Caproni, D. De, D. Didona, K. Drenovska, M. Goebeler, M. Hertl, B. Horváth, M. Kasperkiewicz, D. Kiritsi, M. Larralde, A. V. Marzano, J. Meijer, D. F. Murrell, J. Powell, E. Sprecher, N. S. Chandran, M. M. Tomayko, S. Uzun, N. van Beek, H. Ott, A. Patsatsi, A. Torrelo, A. Welfringer‐Morin, E. Schmidt, P. Joly   +31 more
wiley   +1 more source

Efficacy of deoxyspergualine for antibody-mediated rejection and proteinuria after kidney transplantation

Therapeutics and Clinical Risk Management, 2008
Hideki Ishida, Kazunari TanabeDepartment of Urology, Tokyo Women’s Medical University, Tokyo, JapanAbstract: A patient showing antibody-mediated rejection (AMR) with severe vasculitis, and massive proteinuria after kidney transplantation was ...
Hideki Ishida, Kazunari Tanabe
doaj  

Cryptogenic stroke and patent foramen ovale (abridged and translated version)

Neurological Research and Practice, 2019
Interventional patent foramen ovale (PFO) closure should be performed in patients aged 16 to 60 years (after extensive neurological and cardiological diagnostic work-up) with a history of cryptogenic ischaemic stroke and patent foramen ovale, with ...
Hans-Christoph Diener, Armin Grau, Stephan Baldus   +2 more
doaj   +1 more source

OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders

Journal of the European Academy of Dermatology and Venereology, EarlyView.
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta, Julia Steriopoulos, Vasiliki Economopoulos, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Comparative System Analysis of Parabolic Trough Power Plants with DSG and Oil using Integrated Thermal Energy Storage

, 2011
In addition to the commercial parabolic trough power plants using synthetic oil, the direct steam generation (DSG) is one option for future trough plants.
Laing, Doerte, Schnatbaum-Laumann, Lars, Feldhoff, Jan Fabian, Ortiz-Vives, Francisco, Schmitz, Kai, Eck, Markus, Schulte-Fischedick, Jan   +6 more
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