Results 51 to 60 of about 6,370 (180)
A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics
Andrology, EarlyView.ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis +3 more
wiley +1 more source
Cryptogenic stroke and patent foramen ovale (abridged and translated version)
Neurological Research and Practice, 2019 Interventional patent foramen ovale (PFO) closure should be performed in patients aged 16 to 60 years (after extensive neurological and cardiological diagnostic work-up) with a history of cryptogenic ischaemic stroke and patent foramen ovale, with ...
Hans-Christoph Diener +2 more
doaj +1 more source
Gut microbiota as a novel therapeutic target for eating disorders and obesity
British Journal of Pharmacology, EarlyView.The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė +5 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Site‐specific antibody modification is a useful chemical strategy to elaborate antibody therapeutic function. Conventional lysine‐ or cysteine‐based conjugation methods generate heterogeneous products, while protein engineering approaches are resource‐intensive.
Karolina Krygier +2 more
wiley +1 more source
Study of the Discrete Shear Gap Technique in Timoshenko Beam Elements
Civil Engineering Dimension, 2017 A major difficulty in formulating a finite element for shear-deformable beams, plates, and shells is the shear locking phenomenon. A recently proposed general technique to overcome this difficulty is the discrete shear gap (DSG) technique. In this study,
Foek Tjong Wong, Steven Sugianto
doaj +3 more sources
Financial Management, EarlyView.ABSTRACT We examine how mergers and acquisitions (M&As) enable firms to adapt to climate policy shocks. Exploiting the adoption of the Nitrogen Oxides (NOx) Budget Trading Program (NBP) across US states as an exogenous shock, we find that firms with NOx‐emitting plants subject to the NBP are more likely to engage in M&As, particularly through vertical ...
Samer Adra +3 more
wiley +1 more source
Therapeutics and Clinical Risk Management, 2008 Hideki Ishida, Kazunari TanabeDepartment of Urology, Tokyo Women’s Medical University, Tokyo, JapanAbstract: A patient showing antibody-mediated rejection (AMR) with severe vasculitis, and massive proteinuria after kidney transplantation was ...
Hideki Ishida, Kazunari Tanabe
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