Results 191 to 200 of about 119,642 (302)
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi +6 more
wiley +1 more source
Mathematical modelling of OAS2 activation by dsRNA and effects of dsRNA lengths
The activation of 2'-5'-oligoadenylate synthetase (OAS) enzymes by direct interaction with viral double-stranded RNA (dsRNA) is a key part of the innate immune response to viral infection. The downstream effect of the OAS-dsRNA interaction is to degrade the viral single-stranded RNA (ssRNA) to prevent the spread of the virus.
openaire +1 more source
Sero‐Epidemiology and Molecular Detection of Bluetongue Virus in Goats in Bangladesh
The first large‐scale study in Bangladesh confirmed bluetongue virus infection in goats through combined c‐ELISA and nested RT‐PCR approaches, revealing high seroprevalence and identifying key management‐related risk factors. ABSTRACT Background Bluetongue (BT) is an arthropod‐transmitted, non‐contagious viral disease of domestic ruminants caused by ...
Md Habibur Rahman +5 more
wiley +1 more source
Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract
ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik +3 more
wiley +1 more source
SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity
The SARS‐CoV‐2 nucleocapsid (N) protein is not only the specific viral RNA packaging protein, but also acts as an RNA chaperone, facilitating RNA folding. We show that it facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone.
Sabrina Babl +11 more
wiley +1 more source
Why Is MS a More Frequent Complication of EBV Infection in Females?
ABSTRACT Multiple sclerosis (MS) is a T helper (Th) cell‐mediated disease that targets central nervous system (CNS) white matter. This disease affects three times more females than males. For many years, the etiology of MS was not well understood and the exact nature of the autoimmune reaction was speculative.
Shannon E. Dunn +2 more
wiley +1 more source
dsRNA viruses in Nadsonia fulvescens
Ilona, Pfeiffer +2 more
openaire +3 more sources
Genetic Variation in Chemical Defence Affects Protection of an Herbivorous Insect Against Predation
ABSTRACT Genetic variation contributes to intraspecific differences in the chemical defence in many insect species, yet the underlying genetic mechanisms remain poorly understood. The horseradish flea beetle, Phyllotreta armoraciae, sequesters glucosinolates from its horseradish host plant and activates them using endogenous myrosinase enzymes.
Johannes Körnig +9 more
wiley +1 more source
ABSTRACT Amaranthus palmeri is one of the most troublesome invasive agricultural weeds worldwide, exhibiting super invasiveness and high resistance to conventional management strategies. Artificial microRNA‐mediated silencing technology, coupled with a nanoparticle‐mediated delivery system, represents an attractive approach for fertility control in A ...
Liyong Sun +6 more
wiley +1 more source
Enhancing the delivery and stability of lipid nanoparticle-dsRNA formulations in the RNAi-recalcitrant fall armyworm (<i>Spodoptera frugiperda</i>). [PDF]
Kaarow M +8 more
europepmc +1 more source

