Results 81 to 90 of about 1,165,839 (240)

Deep Sequencing Analysis Reveals the Mycoviral Diversity of the Virome of an Avirulent Isolate of Rhizoctonia solani AG-2-2 IV. [PDF]

open access: yesPLoS ONE, 2016
Rhizoctonia solani represents an important plant pathogenic Basidiomycota species complex and the host of many different mycoviruses, as indicated by frequent detection of dsRNA elements in natural populations of the fungus.
Anika Bartholomäus   +5 more
doaj   +1 more source

CHARACTERIZING dsRNA PRODUCTION IN VIRUS-INFECTED FISH CELLS [PDF]

open access: yes, 2014
Viral dsRNA is produced by almost all viruses sometime during their replicative cycle. These viral nucleic acids are potent inducers of both innate and adaptive immune responses, and are therefore considered important immuno-modulators.
Aloufi, Amal Brek
core  

Influence of cellular dsRNA binding proteins in the replication process of a dsRNA virus

open access: yes, 2012
Die Fragestellung dieser Arbeit war, ob Proteine des Virus der infektiösen Bursitis (IBDV) mit den aviären Proteinen p68 und NF45 (nuclear factor 45) interagieren. Beide Hühnerproteine wurden exprimiert und gereinigt um spezifische Seren herzustellen.
openaire   +2 more sources

Duck Orbivirus and Egg Production: A Newly Identified Duck Orbivirus Is the Etiological Agent of Egg Production Decline in Chinese Breeder Ducks

open access: yesAnimal Research and One Health, EarlyView.
Field samples from breeder duck farms with egg‐production decline were subjected to viral detection, genome sequencing, and virus isolation. Experimental infection demonstrated that duck orbivirus (DORV) causes a significant and persistent reduction in egg production in breeder ducks.
Bing Li   +18 more
wiley   +1 more source

Honey Bee Viruses, Colony Health, and Antiviral Defense

open access: yesProceedings, 2020
Honey bee colony losses are influenced by multiple abiotic and biotic factors, including viruses. To investigate the effects of RNA viruses on honey bees, we infected bees with a model virus (Sindbis-GFP) in the presence or absence of double-stranded RNA
Katie F. Daughenbaugh   +4 more
doaj   +1 more source

In silico and in vitro methods to identify ebola virus VP35-dsRNA inhibitors [PDF]

open access: yesBioorganic & Medicinal Chemistry, 2016
Ebola virus continues to be problematic as sporadic outbreaks in Africa continue to arise, and as terrorist organizations have considered the virus for bioterrorism use. Several proteins within the virus have been targeted for antiviral chemotherapy, including VP35, a dsRNA binding protein that promotes viral replication, protects dsRNA from ...
Jason G, Glanzer   +5 more
openaire   +2 more sources

RNA‐Binding Proteins Shape Mammalian Retroelement RNA Fate: Lessons From HIV‐1, LINE‐1, and Related Reverse‐Transcribing Elements

open access: yesAnimal Research and One Health, EarlyView.
RNA‐binding proteins (RBPs) and RNA‐associated factors shape retroelement RNA fate by regulating RNA processing, translation, RNP assembly and remodeling, reverse transcription, nuclear trafficking, chromatin engagement, and RNA surveillance. These pathways balance productive retroviral replication or retrotransposon insertion with RNA decay ...
Mingrui Li, Zhangyuan Pan, Yongjuan Guan
wiley   +1 more source

Process Analytical Technology (PAT) for Continuous Purification of mRNA via Precipitation and Tangential Flow Filtration

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Continuous downstream processing of messenger ribonucleic acid (mRNA) therapeutics requires purification strategies that are scalable, robust, and capable of removing product‐ and process‐related impurities from in vitro transcription mixtures.
Rajan R. Bhawnani   +8 more
wiley   +1 more source

Avian Toll-like receptor 3 isoforms and evaluation of Toll-like receptor 3–mediated immune responses using knockout quail fibroblast cells

open access: yesPoultry Science, 2020
Toll-like receptor 3 (TLR3) induces host innate immune response on recognition of viral double-stranded RNA (dsRNA). Although several studies of avian TLR3 have been reported, none of these studies used a gene knockout (KO) model to directly assess its ...
Mahesh KC   +8 more
doaj   +1 more source

Translation of the L-species dsRNA genome of the killer-associated virus-like particles of Saccharomyces cerevisiae [PDF]

open access: yes, 2019
Virus-like particles containing the L (P1)-species of double-stranded RNA (dsRNA) were isolated from Saccharomyces cerevisiae, and the translational activity of the virus-like particle-derived dsRNA was analyzed in the wheat germ cell-free system ...
Bostian, Keith A.   +3 more
core  

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