Results 101 to 110 of about 1,165,839 (240)

Structural Basis for the dsRNA Specificity of the Lassa Virus NP Exonuclease

PLoS ONE, 2012
Lassa virus causes hemorrhagic fever characterized by immunosuppression. The nucleoprotein of Lassa virus, termed NP, binds the viral genome. It also has an additional enzymatic activity as an exonuclease that specifically digests double-stranded RNA (dsRNA). dsRNA is a strong signal to the innate immune system of viral infection. Digestion of dsRNA by
Kathryn M Hastie, Liam B King, Michelle A Zandonatti, Erica Ollmann Saphire   +3 more
openaire   +4 more sources

RNA interference of the ecdysone receptor gene AgEcR in a wolfberry ‐ specialized strain of Aphis gossypii Glover affects its survival and fecundity and confers resistance in transgenic goji (Lycium barbarum L.)

Pest Management Science, EarlyView.
AgEcR, an ecdysone receptor from Aphis gossypii, is an RNA interference (RNAi) target. Artificial diet screening of five double ‐ stranded RNA fragments identified dsAgEcR2 targeting the D/E junction as the most potent. Transgenic goji expressing dsAgEcR2 caused molting defects and reduced fecundity, suppressing population growth and offering a ...
Ting Yan, Ao‐Ga Li, Run‐Yao Bai, Long Hai, Shu‐Juan Chang, Ying Zhang, Ri‐Heng Wu   +6 more
wiley   +1 more source

Evolutionary genomics of mycovirus-related dsRNA viruses reveals cross-family horizontal gene transfer and evolution of diverse viral lineages

BMC Evolutionary Biology, 2012
Background Double-stranded (ds) RNA fungal viruses are typically isometric single-shelled particles that are classified into three families, Totiviridae, Partitiviridae and Chrysoviridae, the members of which possess monopartite, bipartite and ...
Liu Huiquan, Fu Yanping, Xie Jiatao, Cheng Jiasen, Ghabrial Said A, Li Guoqing, Peng Youliang, Yi Xianhong, Jiang Daohong   +8 more
doaj   +1 more source

(A,B) Northern gel blot analysis of CYP3-dsRNA and CYP3-dsRNA-derived siRNA accumulation in local and distal (semi-systemic) barley leaf areas.

, 2016
(A) Detection of 791 nt long CYP3-dsRNA precursor in pooled leaf tissue from non-infected leaves using [α-32P]-dCTP labeled CYP3-dsRNA as probe. Local (L) and distal (semi-systemic [S]) leaf segments were sampled separately at the indicated times after ...
John McMillan (3217584), Dagmar Biedenkopf (201484), Aline Koch (3217596), Vinitha Cardoza (3217605), Eltayb Abdellatef (3217602), Lennart Weber (479942), Alexandra Furch (3217590), Karl-Heinz Kogel (54116), Lukas Jelonek (839039), Alexander Goesmann (11354), Lukas Linicus (3217587), Tobias Mentzel (3217593), Jan Johannsmeier (3217581), Oliver Rossbach (3217599)   +13 more
core   +1 more source

Biomaterial Platforms for Spatiotemporal Control of mRNA Delivery in Tissue Engineering and Regenerative Medicine: Design Rules, Therapeutic Applications, and Translational Roadmap

Small, EarlyView.
Biomaterial platforms can control where and when mRNA‐encoded proteins are expressed to support tissue repair. This Review proposes a cargo–target–timing framework linking therapeutic function, target tissues and cells, and expression profiles with carrier and scaffold design.
Huachun Pan, Shumin Yang, Katarina Holubova, Huifang Yin, Hongbo Chen, Xintian Zheng, Xiangan Han, Jinqiu Zhang, Xueping Li, Hui Zhang, Xiaojun Cai, Václav Slovák, Lihong Zhang, Quan Mo, Quazi T. H. Shubhra   +14 more
wiley   +1 more source

A Novel Totivirus Naturally Occurring in Two Different Fungal Genera

Frontiers in Microbiology, 2019
Mycoviruses are widely distributed across different phyla of the fungal kingdom. Viruses that share significant sequence similarities have been reported in different fungi, suggesting descent from a common ancestor.
Mahmoud E. Khalifa, Mahmoud E. Khalifa, Robin M. MacDiarmid, Robin M. MacDiarmid   +3 more
doaj   +1 more source

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source

A third cryptic virus in beet (Beta vulgaris )

, 1993
Japanese leaf beet Beta vulgaris var. cicla cv. Fudanso plants were found to contain four double-stranded RNA (dsRNA) components in apparently healthy beet plants.
White, R. F., Antoniw, J. F., Woods, R. D., Xie, W. S., Antoniw, John   +4 more
core   +1 more source

LsFAMeT and LsJHAMT coordinate JH biosynthesis to regulate fecundity in Laodelphax striatellus

Insect Science, EarlyView.
The small brown planthopper (SBPH), Laodelphax striatellus, can trigger large‐scale outbreaks when encountering suitable habitats during migration due to their strong reproductive ability. This study investigated the role of juvenile hormone (JH) in regulating SBPH reproduction.
Yan Guo, Bing‐Bing Shi, Xue‐Qi Zhang, Qiong Yang   +3 more
wiley   +1 more source

Perbaikan Metode Ekstraksi dsRNA Virus secara Sederhana untuk RT-PCR Tiga Virus Tumbuhan

, 2018
Replicative form (RF) of RNA viruses are dsRNA structured nucleic acid, always found in plants infected by RNA virus. The principle of dsRNA extraction is based on the different affinity of nucleic acids for the cellulose powder and the specific ...
Wiwik Endarsih, Sri Sulandari, Sedyo Hartono   +2 more
core   +1 more source