Results 121 to 130 of about 1,165,839 (240)

Characteristics of dsRNA genome segments (cDNA copy) and proteins of the bluetongue virus serotype 26 Kuwait (KUW2010/02).

, 2013
Characteristics of dsRNA genome segments (cDNA copy) and proteins of the bluetongue virus serotype 26 Kuwait (KUW2010/02).
Sushila Maan (177215), Manjunatha N. Belaganahalli (177211), Narender S. Maan (177220), Katarzyna Bachanek-Bankowska (199876), Peter P. C. Mertens (177259), Kyriaki Nomikou (177223), Houssam Attoui (177251), Eva Veronesi (195523)   +7 more
core   +1 more source

Segregation of Citrus Tristeza Virus Strains Evidenced by Double Stranded RNA (dsRNA) Analysis [PDF]

, 1991
A field isolate of citrus tristeza virus (CTV), T-385, was separated from other virus and virus-like diseases by aphid transmission to Mexican lime seedlings.
Ballester-Olmos, José F., Ballester-Olmos, J. F., Guerri, José, Moreno, P., Guerri, J., Moreno, Pedro, Martínez, M. E., J. Guerri, J. F. Ballester-Olmos, Moreno, P. ; Guerri, J. ; Ballester-Olmos, J. F. ; Martínez, M. E., M. E. Martínez, P. Moreno   +11 more
core   +1 more source

Generation of Virus- and dsRNA-Derived siRNAs with Species-Dependent Length in Insects

Viruses, 2019
Double-stranded RNA (dsRNA) molecules of viral origin trigger a post-transcriptional gene-silencing mechanism called RNA interference (RNAi). Specifically, virally derived dsRNA is recognized and cleaved by the enzyme Dicer2 into short interfering RNAs (siRNAs), which further direct sequence-specific RNA silencing, ultimately silencing replication of ...
Dulce Santos, Lina Mingels, Elise Vogel, Luoluo Wang, Olivier Christiaens, Kaat Cappelle, Niels Wynant, Yannick Gansemans, Filip Van Nieuwerburgh, Guy Smagghe, Luc Swevers, Jozef Vanden Broeck   +11 more
openaire   +5 more sources

Matrine–Tea Saponin Synergism Involves Suppressed Detoxification and Digestion in a Leaf Beetle

Integrative Zoology, EarlyView.
Tea saponin and matrine showed synergistic toxicity against Plagiodera versicolora. Combined exposure suppressed digestion‐ and detoxification‐related processes, while silencing the trypsin gene Pver105950 and chitinase gene Pver001190 increased larval susceptibility to tea saponin and matrine, respectively.
Owais Khan, Xiayu Li, Yanping Zhang, Runhua Han, Letian Xu   +4 more
wiley   +1 more source

(A,B) RNA profiling (RNAseq analysis) of CYP3-dsRNA-derived RNAs in local and distal tissue of CYP3-dsRNA-treated barley leaves on Illumina HiSeq.

, 2016
Higher numbers of reads of CYP3-dsRNA-derived sRNAs were found in infected vs. non-infected leaves both in the sprayed (local [A]) and non-sprayed (semi-systemic [B]) leaf area at 6 dpi with strain Fg-IFA65.
John McMillan (3217584), Dagmar Biedenkopf (201484), Aline Koch (3217596), Vinitha Cardoza (3217605), Eltayb Abdellatef (3217602), Lennart Weber (479942), Alexandra Furch (3217590), Karl-Heinz Kogel (54116), Lukas Jelonek (839039), Alexander Goesmann (11354), Lukas Linicus (3217587), Tobias Mentzel (3217593), Jan Johannsmeier (3217581), Oliver Rossbach (3217599)   +13 more
core   +1 more source

dsRNA-Seq: Identification of Viral Infection by Purifying and Sequencing dsRNA [PDF]

, 2019
RNA viruses are a major source of emerging and re-emerging infectious diseases around the world. We developed a method to identify RNA viruses that is based on the fact that RNA viruses produce double-stranded RNA (dsRNA) while replicating. Purifying and
Roy Parker, Mark D. Stenglein, Sara L. Sawyer, Laura L. Hoon-Hanks, Alex C. Stabell, Decker, Carolyn J., Morrison, Thomas E., Parker, Roy, Steiner, Halley R., Carolyn J. Decker, Kelsey C. Haist, Haist, Kelsey C., Hoon-Hanks, Laura L., Stabell, Alex C., James H. Morrison, Sawyer, Sara L., Morrison, James H., Halley R. Steiner, Stenglein, Mark D., Eric M. Poeschla, Thomas E. Morrison, Poeschla, Eric M.   +21 more
core   +1 more source

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

Cryo-EM reveals a previously unrecognized structural protein of a dsRNA virus implicated in its extracellular transmission. [PDF]

PLoS Pathog, 2021
Shao Q, Jia X, Gao Y, Liu Z, Zhang H, Tan Q, Zhang X, Zhou H, Li Y, Wu, Zhang Q.   +10 more
europepmc   +1 more source

SLAMF6 Enhances the Efficacy of Anti‐PD‐L1 Immunotherapy in CRC Through the STAT1/CXCL10 Signaling Axis

Cancer Science, EarlyView.
SLAMF6 recruits SHP‐2 to activate STAT1, upregulates CXCL10 and PD‐L1, promotes CD8+T cell infiltration, and enhances the efficacy of anti‐PD‐L1 therapy. ABSTRACT As a T‐cell receptor co‐stimulatory protein, signaling lymphocyte activation molecule family 6 (SLAMF6) is a member of the immune cell activating receptor family and is expressed on T cells ...
Yu Wu, Xinhui Lv, Shunhao Zhang, Yafang Chen, Sicong Liu, Feiyang Song, Chunmei Zhao, Guihua Wang, Xudong Wang   +8 more
wiley   +1 more source

Limitations in harnessing oral RNA interference as an antiviral strategy in Aedes aegypti

iScience
Summary: Mosquitoes, particularly Aedes aegypti, are critical vectors for globally significant pathogenic viruses. This study examines the limitations of oral RNA interference (RNAi) as a strategy to disrupt viral transmission by Ae. aegypti.
Ottavia Romoli, Annabelle Henrion-Lacritick, Hervé Blanc, Lionel Frangeul, Maria-Carla Saleh   +4 more
doaj   +1 more source