Results 91 to 100 of about 4,194,149 (156)

DTI-ALPS is not independently associated with overall survival beyond established prognostic factors in glioblastoma

Purpose Impaired glymphatic function has been associated with shorter survival in glioblastoma. However, the relationship between glymphatic dysfunction and survival has not yet been evaluated in the context of established prognostic ...
Leon Schmidt, Max Jägersberg, Bianca Kollmann, Katrin Frauenknecht, Sebastian Altmann, Ahmed E. Othman, Harald Krenzlin, Andrea Kronfeld, Sascha D. Santaniello, Marc A. Brockmann, Oliver Tüscher, Tüscher, Oliver, Schmidt, Leon, Frauenknecht, Katrin, Altmann, Sebastian, Brockmann, Marc A, Kronfeld, Andrea, Othman, Ahmed E, Santaniello, Sascha D, Krenzlin, Harald, Kollmann, Bianca, Jägersberg, Max   +21 more
core   +1 more source

Evaluation of conductivity tensor image along the perivascular space in the brains of patients with cognitive impairments

Frontiers in Aging Neuroscience
BackgroundThe diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) index has been proposed as an imaging marker of impaired perivascular water transport across the Alzheimer’s disease (AD) continuum. Whether a conductivity-based ALPS
Jehyeuk Ahn, Sang-Young Kim, Mun Bae Lee, Oh-In Kwon, Hak Young Rhee, Yu Jin Jung, Yoon Kim, Soonchan Park, Chang-Woo Ryu, Jinseok Lee, Geon-Ho Jahng   +10 more
doaj   +1 more source

Dynamic changes in glymphatic function in reversible cerebral vasoconstriction syndrome

The Journal of Headache and Pain
Background The pathophysiology of the reversible cerebral vasoconstriction syndrome (RCVS) remains enigmatic and the role of glymphatics in RCVS pathophysiology has not been evaluated.
Chia-Hung Wu, Yu Kuo, Yu-Hsiang Ling, Yen-Feng Wang, Jong-Ling Fuh, Jiing-Feng Lirng, Hsiu-Mei Wu, Shuu-Jiun Wang, Shih-Pin Chen   +8 more
doaj   +1 more source

Harnessing Brain Age-Specific Effects on the Associations Between Sleep Quality, Glymphatic Function, and Cognition in Normal Ageing Adults: Insights for Gerotherapeutics

Neurology and Therapy
Introduction The interplay between glymphatic function and sleep quality is crucial for brain health and cognitive longevity in late adulthood. Beyond chronological age, whether brain age has specific effects on the associations between glymphatic ...
Hanna Lu, Zeyan Li, Liwei Guo, Xi Ni, Ben Chen, Xiaomei Zhong, Yanling Zhou, Yuping Ning   +7 more
doaj   +1 more source

Decreased diffusivity along the perivascular spaces in bipolar disorder: an MRI-based cross-sectional and Mendelian randomization study

Translational Psychiatry
The pathophysiology of bipolar disorder (BD) remains unclear. We investigated whether diffusion tensor imaging along perivascular spaces (DTI-ALPS), a putative MRI marker of glymphatic function, is altered in BD and whether this index relates to ...
Zhuohui Chen, Ziwei Teng, Yan Qiu, Sujuan Li, Xuelei Xu, Min Yang, Jindong Chen, Dong Yang, Hao Li   +8 more
doaj   +1 more source

DTI-ALPS alterations in cerebral small vessel disease: Associations with executive deficits and gait disorders via white matter injury

Neurobiology of Disease
Cerebral small vessel disease (CSVD) is a major cause of executive dysfunction and gait disturbances in older adults, with white matter injury being a key contributor.
Shujian Chen, Xianfeng Yu, Qiuju Gong, Jing Cao, Jiajia Qin, Yayu Wang, Zhongwu Sun, Xia Zhou, Xiaoqun Zhu   +8 more
doaj   +1 more source

DTI-ALPS index and cognitive impairment in cerebral small vessel disease: a systematic review and meta-analysis

Objective The diffusion tensor image analysis along the perivascular space (DTI-ALPS) index is a non-invasive diffusion tensor imaging-based metric proposed to reflect glymphatic processes.
Xiao-xue Zeng, Xia He, Ming-xi Xu, Xia-lian Huang, Fu-li Qin, Yan-qiu Wang, Ying-ying Yang, Feng-le Mao   +7 more
core   +1 more source

Impairment of the intracranial lymphatic system in Parkinson’s disease: a combined study of the meningeal lymphatics vessels and glymphatic system based on noninvasive neuroimaging

European Journal of Medical Research
Background The role of intracranial lymphatic circulation in Parkinson’s disease (PD) causes more and more concerns nowadays. The drainage function of meningeal lymphatic vessels (MLVs) and the clearance capability of the glymphatic system have been ...
Mingxian Huang, Pan Zhang, Zhen Chen, Xiaoyang Wang, Hui Li, Shangwen Xu, Limin Lan, Wenxi Zheng, Hui Xiao   +8 more
doaj   +1 more source

Evaluation of the glymphatic system using the DTI-ALPS index in type 2 diabetes mellitus-induced cognitive impairment

Journal of Clinical Imaging Science
Objectives: The objective of the study is to assess the utility of the perivascular space diffusion tensor imaging - along the perivascular space (DTI-ALPS) index in evaluating the activity of the brain glymphatic system in patients with type 2 diabetes mellitus (T2DM) and cognitive impairment.
Wang, Nan, Yin, Rendi, Fang, Yao, Wei, Xiaole, Shen, Li, Feng, Wei, Lv, Haorui, Zhou, Xiaoyan, Zhang, Chao, Ying, Changjiang, Liu, Xuan   +10 more
openaire   +3 more sources

Association between early serum uric acid levels and diffusion tensor imaging analysis along the perivascular space with cognitive function

Brain-X
Serum uric acid (SUA) demonstrates dual roles as both an antioxidant and a pro‐oxidant; however, its long‐term effects on glymphatic function and cognitive performance remain unclear.
Tong Zhang, Han Lv, Ying Hui, Xinyu Zhao, Na Zeng, Ning Wu, Mingze Xu, Max Wintermark, Jing Sun, Shuohua Chen, Jing Li, Xiaoshuai Li, Shouling Wu, Liufu Cui, Zhenchang Wang, Yanying Liu   +15 more
doaj   +1 more source