Results 61 to 70 of about 15,990,582 (283)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

A new intuitionism: Meaning, memory, and development in Fuzzy-Trace Theory

open access: yesJudgment and Decision Making, 2012
Combining meaning, memory, and development, the perennially popular topic of intuition can be approached in a new way. Fuzzy-trace theory integrates these topics by distinguishing between meaning-based gist representations, which support fuzzy (yet ...
Valerie F. Reyna
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Research on dual process theory based telecom augmented cognition

open access: yesDianxin kexue
Incorporating the current works in augmented large language models (LLM), a dual process theory based telecom augmented cognition architecture (TACA) was proposed.This architecture addressed challenges faced by LLM in the field of telecom, such as lack ...
Xiaoxing LIAN   +5 more
doaj   +2 more sources

Debiasing in motion: Boosting sound intuiting through animated video training

open access: yesActa Psychologica
Recent debiasing studies have shown that an explanation of the correct solution to a reasoning problem can often improve the performance of initially biased reasoners. However, most of these training studies have relied on text-based interventions. While
Nina Franiatte   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Concepts, Perception and the Dual Process Theories of Mind

open access: yesBaltic International Yearbook of Cognition, Logic and Communication, 2014
In this article we argue that the problem of the relationships between concepts and perception in cognitive science is blurred by the fact that the very notion of concept is rather confused. Since it is not always clear exactly what concepts are, it is not easy to say, for example, whether and in what measure concept possession involves entertaining ...
FRIXIONE, Marcello, LIETO, ANTONIO
openaire   +5 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Cognitive Demands And the EFL Writer: Observations on Kind, Degree, and Agency

open access: yesIkala: Revista de Lenguaje y Cultura, 2014
Research into understanding the process through which EFL writers revise texts have centered on matters of degree: of cognitive capacity and complexity or volume of tasks.
Juan David Gómez González
doaj  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

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