Results 41 to 50 of about 1,324,687 (286)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Beyond “fake news”: Analytic thinking and the detection of false and hyperpartisan news headlines [PDF]

open access: yesJudgment and Decision Making, 2021
Why is misleading partisan content believed and shared? An influential account posits that political partisanship pervasively biases reasoning, such that engaging in analytic thinking exacerbates motivated reasoning and, in turn, the acceptance of ...
Robert M. Ross   +2 more
doaj  

Duality Theory for Portfolio Optimisation under Transaction Costs [PDF]

open access: yes, 2014
For portfolio optimisation under proportional transaction costs, we provide a duality theory for general cadlag price processes. In this setting, we prove the existence of a dual optimiser as well as a shadow price process in a generalised sense.
Czichowsky, Christoph   +1 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Strong Subadditivity, Null Energy Condition and Charged Black Holes [PDF]

open access: yes, 2014
Using the Hubeny-Rangamani-Takayanagi (HRT) conjectured formula for entanglement entropy in the context of the AdS/CFT correspondence with time-dependent backgrounds, we investigate the relation between the bulk null energy condition (NEC) of the stress ...
Caceres, Elena   +3 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Accuracy of ‘My Gut Feeling:’ Comparing System 1 to System 2 Decision-Making for Acuity Prediction, Disposition and Diagnosis in an Academic Emergency Department

open access: yesWestern Journal of Emergency Medicine, 2015
Introduction: Current cognitive sciences describe decision-making using the dual-process theory, where a System 1 is intuitive and a System 2 decision is hypothetico-deductive.
Daniel Cabrera   +6 more
doaj   +1 more source

Self-disclosure on social networks: More than a rational decision-making process

open access: yesCyberpsychology: Journal of Psychosocial Research on Cyberpspace, 2022
Although consequences of sharing personal information can be negative and severe (e.g., identity theft), individuals still engage in extensive self-disclosures on social networks.
Sina Ostendorf   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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