Results 81 to 90 of about 757,573 (291)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
International Journal of Integrated CareIntroduction: This study explores the challenges faced by healthcare professionals in providing integrated care for individuals living with co-occurring schizophrenia and type 2 diabetes in Denmark.
Tanja Juhl Mikkelsen +3 more
doaj +1 more source
Substance misuse assessment in mental health services: the importance of professional curiosity [PDF]
, 2017 Co-morbidity of mental health and substance misuse problems (or "Dual Diagnosis") is highly prevalent in mental health and drug treatment services. The parallel approach, where the two conditions are treated at the same time in separate services, is the ...
Milani, Raffaella Margherita +1 more
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Journal of Patient-Reported OutcomesBackground The Dermatology Life Quality Index (DLQI) was designed to be a simple, practical questionnaire for routine clinical use and is the most widely used tool to measure the burden of skin diseases and assess effectiveness of interventions based on ...
Jeffrey Johns +5 more
doaj +1 more source
Neural Regeneration Research, 2015 The transplantation of polylactic glycolic acid conduits combining bone marrow mesenchymal stem cells and extracellular matrix gel for the repair of sciatic nerve injury is effective in some respects, but few data comparing the biomechanical factors ...
Yang Wang +4 more
doaj +1 more source
Towards declarative diagnosis of constraint programs over finite domains [PDF]
, 2003 The paper proposes a theoretical approach of the debugging of constraint programs based on a notion of explanation tree. The proposed approach is an attempt to adapt algorithmic debugging to constraint programming.
Ferrand, Gerard +2 more
core +1 more source
The diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combination with CA125 in the differential diagnosis of ovarian masses [PDF]
, 2011 Background: Cancer antigen 125 (CA125) is the best known single tumor marker for ovarian cancer (OC). We investigated whether the additional information of the human epididymis protein 4 (HE4) improves diagnostic accuracy.
Burges, Alexander +9 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Neural Regeneration Research, 2015 The morphological changes that occur in the taste buds after denervation are not well understood in rats, especially in the contralateral tongue epithelium.
Yi-ke Li +4 more
doaj +1 more source