Results 61 to 70 of about 662,452 (292)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Cognitive Remediation Interventions in Schizoaffective Disorder: A Systematic Review

open access: yesFrontiers in Psychiatry, 2018
Background: Patients with schizoaffective disorder (SAD) suffer from cognitive impairment, which negatively influences their functionality. Cognitive remediation (CR) interventions have been shown to be effective in patients with schizophrenia (SZ) and ...
Ester Lopez-Fernandez   +13 more
doaj   +1 more source

Group Motivational Interviewing as a Psychotherapeutic Intervention for Dual Diagnosis Patients Living with a Psychotic Disorder: Critique of the Literature [PDF]

open access: yes, 2012
Studies indicate that 50% of individuals living with a psychotic disorder also meet Diagnostic and Statistical Manual IV Text Revision (DSM-IV-TR) criteria for substance abuse disorder during their lifetime (Green, Drake, Brunette, & Noordsy, 2007 ...
Stauder, Alexander D
core   +1 more source

Family Interaction Styles of Children with Depressive Disorders, Schizophrenia-Spectrum Disorders, and Normal Controls

open access: yes, 1999
Family interaction processes during a problem-solving task were examined in children with depressive disorders, children with schizophrenia-spectrum disorders, and a normal control group of community children screened for the absence of psychiatric ...
Asarnow, Joan   +2 more
core   +1 more source

Protein folding disorders: Toward a basic biological paradigm [PDF]

open access: yes, 2010
Mechanistic 'physics' models of protein folding fail to account for the observed spectrum of protein folding and aggregation disorders, suggesting that a more appropriately biological paradigm will be needed for understanding the etiology ...
Rodrick Wallace
core   +3 more sources

RELATIONSHIP BETWEEN DUAL DISORDERS AND SLEEP DISORDERS

open access: yesLIBRO COMUNICACIONES, 2021
Objectives Study the relationship between Dual Disorders and Sleep Disorders Describe the most frequent Sleep Disorders amongst substance dependent patients. Material and methods A database was designed, providing the clinical information obtained from the entry sheets of 398 drug dependent patients during their first visit to the Addictions Unit ...
openaire   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Poor sleep quality and progression of gait impairment in an incident Parkinson’s disease cohort [PDF]

open access: yes, 2017
Abnormal sleep may associate with cognitive decline in Parkinson's disease (PD). Furthermore, sleep dysfunction may associate with worse motor outcome.
Anderson, Kirstie N.   +8 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Psychiatric comorbidity in patients with substance use disorder: A hospital-based study

open access: yesIndian Journal of Social Psychiatry, 2017
Background: Pattern of substance use, profile of substance users, and treatment-seeking differ across cultures and continents. These differences could potentially affect the pattern and perhaps prevalence of dual diagnosis.
Ab Majid Gania   +5 more
doaj   +1 more source

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