Cognitive Remediation Interventions in Schizoaffective Disorder: A Systematic Review
Background: Patients with schizoaffective disorder (SAD) suffer from cognitive impairment, which negatively influences their functionality. Cognitive remediation (CR) interventions have been shown to be effective in patients with schizophrenia (SZ) and ...
Ester Lopez-Fernandez +13 more
doaj +1 more source
Psychiatric comorbidity among patients attending an addiction treatment center in Morocco
Introduction The comorbidity between psychiatric disorders and substance use disorders is more and more common in daily clinical practice. However, only few studies have adressed this subject in north african patients.
A. Jelti +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Types of treatment and effects of treatment for dual diagnoses clients: a survey of community support professionals [PDF]
Plan BA literature review of the topic dual diagnoses and the treatment options available to community support professionals was conducted. The survey explored the treatment options available to clinical coordinators and case managers who work for ...
Olson, Diane L.
core
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The impact of COVID-19 on community neurology patients [PDF]
BackgroundThe COVID-19 pandemic has had a worldwide impact. People with neurological disorders are at an increased risk of severe infection and consequent mortality.
Allana Louise Gurney; Neurodegenerative Disorders Research Pty Ltd +1 more
core
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
A reconfigurable wideband and multiband antenna using dual-patch elements for compact wireless devices [PDF]
This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 IEEEA reconfigurable wideband and multiband C-Slot patch antenna with dual-patch elements is proposed and studied.
AbuTarboush, HF +26 more
core +1 more source
Psychiatric comorbidity in patients with substance use disorder: A hospital-based study
Background: Pattern of substance use, profile of substance users, and treatment-seeking differ across cultures and continents. These differences could potentially affect the pattern and perhaps prevalence of dual diagnosis.
Ab Majid Gania +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

