Results 71 to 80 of about 2,492,581 (284)

A comprehensive study of dual diagnosis and counseling clients with chemical dependency and depression [PDF]

, 2007
Includes bibliographical ...
Hoogheem, Lisa
core  

Knowledge and therapeutic gaps : a public health problem in the rare coagulation disorders population

, 2011
Rare coagulation disorders (RCDs) present a considerable and multifaceted public health risk. Although inherited RCDs affect a minor segment of any local healthcare delivery system, their global impact is major and highlight the challenges of delivering ...
J. M. Soucie, Clotting Disorders Working Group, UDC Rare Bleeding, D. M. Dimichele, the European Network Rare Bleeding Disorders Database, A. D. Shapiro, D. J. Aschman, F. Peyvandi   +7 more
core   +1 more source

Additive effect of cerebrolysin and amantadine on disorders of consciousness secondary to acquired brain injury: A retrospective case-control study

Journal of Rehabilitation Medicine, 2020
Background: Acquired brain injury can cause disorders of consciousness. An additive effect of cerebrolysin and amantadine has been postulated, but not systematically studied.
Seunghwan Lee, Hyun Haeng Lee, Yejin Lee, Jongmin Lee   +3 more
doaj   +1 more source

Evaluation of plasma cytokines in patients with cocaine use disorders in abstinence identifies transforming growth factor alpha (TGFα) as a potential biomarker of consumption and dual diagnosis [PDF]

PeerJ, 2017
Background Cocaine use disorder (CUD) is a complex health condition, especially when it is accompanied by comorbid psychiatric disorders (dual diagnosis). Dual diagnosis is associated with difficulties in the stratification and treatment of patients. One
Rosa Maza-Quiroga, Nuria García-Marchena, Pablo Romero-Sanchiz, Vicente Barrios, María Pedraz, Antonia Serrano, Raquel Nogueira-Arjona, Juan Jesus Ruiz, Maribel Soria, Rafael Campos, Julie Ann Chowen, Jesus Argente, Marta Torrens, Meritxell López-Gallardo, Eva María Marco, Fernando Rodríguez de Fonseca, Francisco Javier Pavón, Pedro Araos   +17 more
doaj   +2 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Dual disorders: an overview

Irish Journal of Psychological Medicine
Abstract The coexistence of substance use disorders (SUD) and other mental disorders – commonly referred to as dual disorders (DD) – is highly prevalent and clinically significant. Although various terms have been used over time (e.g., psychiatric comorbidity, dual pathology), the lack of a standardised definition has created ...
Torrens, Marta, Fonseca Casals, Francina, Gonzalez-Saiz, Francisco, Mestre-Pintó, Juan Ignacio   +3 more
openaire   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Prevalence of dual diagnosis in the south of Peru: descriptive clinical study

Interacciones, 2016
Comorbidity between substance use disorders and other psychiatric disorders or dual diagnosis (PD) is characterized by difficulty in their therapeutic approach, constant relapses and hospital admissions, as well as higher violent and criminal behavior ...
Jonathan A. Zegarra-Valdivia, Brenda Nadia Chino Vilca, Ernesto Cazorla Perez   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Exploring 'dual diagnosis' treatment motivation [PDF]

, 2011
Section A reviews the clinical and risk implications of dual diagnosis along with the treatment context. The value of gathering firsthand accounts of service users to inform the planning and delivery of healthcare is touched on.
Ward, M.
core