Results 91 to 100 of about 1,157 (239)

Polymerized Pro‐Estrogen Microneedles via Two Photon Polymerization

open access: yesMacromolecular Rapid Communications, EarlyView.
Acrylic pro‐drugs of 17β‐estradiol were subjected to spatially controlled two‐photon polymerization to create bespoke microneedle geometries with potential biomedical applications for long‐term transdermal hormone delivery. ABSTRACT Two‐photon polymerization (TPP) is a powerful technique to create microscale structures with high precision, offering ...
Yang Lou   +6 more
wiley   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu   +4 more
wiley   +1 more source

Clinically Feasible White Matter Fiber Tractography in Peritumoral Zones With Cerebral Vasogenic Edema

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose In diffusion MRI, vasogenic edema manifests as a major fraction of isotropic water that dilutes the anisotropic intra‐axonal portion of the signal. Many tractography algorithms mistake vasogenic edema for the white matter boundary and terminate tracking to prevent producing spurious streamlines.
Patryk Filipiak   +6 more
wiley   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

open access: yesChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel   +5 more
wiley   +1 more source

Dubbing

open access: yes, 2018
Dubbing has been practised for many years all over the world. As Chaume points out, it is ‘one of the oldest modes of ‘AVT’ and ‘it origins can be traced back to the late 1920’s’ (2012: 1); as a matter of fact, it is when ‘written language on screen in silent movies were introduced, with intertitles, that translation becomes essential to the full ...
openaire   +1 more source

How AI and Digital Technologies Can Enhance Sustainable Livestock Manure Management: An Overview From Treatment to Distribution

open access: yesSustainable Development, EarlyView.
ABSTRACT Sustainable livestock manure management sits at the nexus of climate, nutrient circularity and water quality. This review explores how artificial intelligence (AI) and digital platforms are used across four management stages, that is, treatment, storage, valorisation and distribution, and figures out where integration fails to deliver ...
Zhan Shi   +3 more
wiley   +1 more source

Recycled Thermocol Nanofibers Based Smart Triboelectric Nanogenerators for AI‐Assisted Switching

open access: yesSmall, EarlyView.
Waste expanded polystyrene is recycled into electrospun nanofibers for a sustainable triboelectric nanogenerator. The device exhibits enhanced surface morphology, improved triboelectric output, and multifunctional applications including energy harvesting, self‐powered sensing, and intelligent human‐machine interfaces using lightweight, flexible, and ...
Shubham V. Patil   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy