Results 91 to 100 of about 957 (170)

Case Report: Successful salvage therapy with sulbactam-durlobactam combined with meropenem for carbapenem-resistant Acinetobacter baumannii bloodstream infection in a child after failure of allogeneic hematopoietic stem cell transplantation

Frontiers in Pediatrics
Bloodstream infections (BSI) caused by carbapenem-resistant Acinetobacter baumannii (CRAB) constitute a serious complication in patients undergoing hematopoietic stem cell transplantation (HSCT), with pediatric patients facing particularly formidable ...
Qian Zhang, Chunjing Wang, Zhiheng Ding, Jiayi Lyu, Yu Zhang, Fangyuan Lai, Ruihao Zheng, Sixi Liu   +7 more
doaj   +1 more source

The epidemiological and molecular characteristics and sulbactam-durlobactam susceptibility of carbapenem-resistant Acinetobacter baumannii in a Chinese teaching hospital

Journal of Global Antimicrobial Resistance
: Objectives: This study aimed to investigate sulbactam-durlobactam (SUL-DUR) susceptibility and molecular features of carbapenem-resistant Acinetobacter baumannii (CRAB) isolates from a Shenzhen teaching hospital. Methods: A retrospective study on CRAB
Hanlian Huang, Qiaomin Zhang, Shaobo Li, Xiaoyan Dai, Zhongbiao Chen, Guili Zhang, Wen Ma, Hongwei Shen   +7 more
doaj   +1 more source

Successful Treatment of OXA-23 Acinetobacter baumannii Pneumonia with Sulbactam-Durlobactam in a Liver Transplant Recipient

Infection and Drug Resistance
Liver transplant recipients face a higher risk of multidrug-resistant (MDR) infections because of preoperative comorbidities, extensive antibiotic use, immunosuppressive therapy, and prolonged mechanical ventilation. Carbapenem-resistant Acinetobacter baumannii (CRAB) remains one of the most challenging pathogens in this group.
Guangjiao Yin, Zhongzhong Liu, Zhen Fu, Zibiao Zhong, Shaojun Ye, Huaqin Pan   +5 more
openaire   +2 more sources

New Antibiotics for Lower Respiratory Tract Infections

Microbiology Research
Respiratory tract infections are frequently encountered in clinical practice. The growing incidence of antimicrobial resistance among the causative pathogens exerts sustained pressure on the existing therapeutic options.
Despoina Papageorgiou, Maria Gavatha, Dimitrios Efthymiou, Eleni Polyzou, Aristotelis Tsiakalos, Karolina Akinosoglou   +5 more
doaj   +1 more source

P-1215. In vitro activity of Sulbactam-durlobactam and Standard-of-Care Antibiotics against Acinetobacter baumannii-calcoaceticus complex isolates from wound and urinary tract sources: ACNBio Study 2023-2025 [PDF]

Open Forum Infect Dis
Background Acinetobacter baumannii most often causes nosocomial bacteremia and pneumonia. However, A. baumannii is becoming an important cause of a broader range of infections including skin and soft tissue infection (SSTI) and urinary tract infections ...
Kirn, Thomas, Chavez, Violeta, Westblade, Lars, Mutnal, Manohar B, Potula, Raghava, Daniels, Anne R, Pierce, Virginia M, Beck, Eric T, Narayanan, Navaneeth, Simner, Patricia J, Cyr, Elizabeth, Fisher, Mark, Argotsinger, Jill, Dumm, Rebekah, Gialanella, Philip, Kufel, Wesley D, Chamberland, Robin R, Marino, Jamie, Huse, Holly, Abbo, Lilian M, Hamilton-Seth, Robert, Riddell, Scott W, Jenkins, Timothy C, Harrington, Amanda, Asempa, Tomefa E, Hankins, Julia, Tibbetts, Robert, Vu, Christine A, Tekle, Tsigereda, Humphries, Romney, Clark, Andrew E, Mochon, Brian, Nicolau, David P, Martinez, Octavio, Hand, Jonathan, Liesman, Rachel   +35 more
europepmc   +2 more sources

Evolution of an extensively antibiotic resistant sublineage of lineage 1 of GC1 Acinetobacter baumannii

npj Antimicrobials and Resistance
The multiply antibiotic-resistant lineage 1 of Acinetobacter baumannii global clone 1 (GC1) emerged in the 1970s, and subsequently more extensively resistant sublineages have emerged.
Christopher J. Harmer, Ting L. Luo, Francois Lebreton, Patrick T. McGann, Ruth M. Hall   +4 more
doaj   +1 more source

What do We Know so Far about Ges Carbapenemases, and What Threat do They Pose?

Postępy Mikrobiologii
Carbapenemases, classified as bacterial enzymes, have the ability to hydrolyze carbapenems – important broad-spectrum antibiotics. This work attempts to summarize the information on the diversity of Guiana Extended-Spectrum (GES) subgroup of ...
Rutkowski Kamil, Osnytskyy Anton, Ślifierska Magdalena, Jarząbek Paulina, Bielec Filip, Pastuszak-Lewandoska Dorota, Brauncajs Małgorzata   +6 more
doaj   +1 more source

Relative inhibitory activities of newly developed diazabicyclooctanes, boronic acid derivatives, and penicillin-based sulfone β-lactamase inhibitors against broad-spectrum AmpC β-lactamases

The relative inhibitory activities of diazabicyclooctanes (avibactam, relebactam, zidebactam, nacubactam, durlobactam), boronic acid derivatives (vaborbactam, taniborbactam, xeruborbactam), and penicillin-based sulfone derivative enmetazobactam were ...
Le Terrier, Christophe, Sadek, Mustafa, Mlynarcik, Patrik, Nordmann, Patrice, Poirel, Laurent   +4 more
core   +1 more source

In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals

The activity of a novel β-lactamase inhibitor combination, sulbactam-durlobactam (SUL-DUR), was tested against 87 colistin-resistant and/or cefiderocol-non-susceptible carbapenem-resistant Acinetobacter baumannii clinical isolates collected from U.S ...
Cober, Eric, Hill, Carol, van Duin, David, Herc, Erica S, Bonomo, Robert A, Greenwood-Quaintance, Kerryl E, Chambers, Henry F, Arias, Cesar A, Fowler, Erin L, Baum, Keri, Doi, Yohei, Fowler, Vance G, Patel, Robin, McElheny, Christi L, Iovleva, Alina   +14 more
core   +1 more source

Sulbactam-Durlobactam for Carbapenem-resistant <i>Acinetobacter baumannii</i> in India: Does Local Molecular Epidemiology Support Current Guideline Recommendations? [PDF]

Indian J Crit Care Med
Mukkelli VG, Gupta R.
europepmc   +1 more source