P41 Combating periodontal disease:chitosan-FK13a1 microparticles as a promising antibiotic alternative [PDF]
Background: Due to antibiotic resistance in the present era the treatment of bacterial infections has become difficult. In dentistry, irregular administration of antibiotics has complicated the treatment of dental and periodontal infections.
Grant, Melissa +2 more
core +1 more source
Focusing on the Basic Principles of Dialysis to Optimize Antibiotic Therapy during Renal Replacement Therapy in Critically Ill Patients [PDF]
Bacterial infections frequently occur in patients in the ICU undergoing renal dialysis using extracorporeal procedures (KRT) that can be applied for different time periods, such as Prolonged Intermittent Renal Replacement Therapy (PIRRT) or Continuous ...
Biancone, L., Mariano, F., Mella, A.
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Antimicrobial Resistance in ESKAPE Pathogens: A Retrospective Epidemiological Study at the University Hospital of Palermo, Italy [PDF]
Background: Antimicrobial resistance (AMR) is an escalating global health threat, projected to cause over 40 million deaths by 2050. ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii ...
Bono E. +11 more
core +1 more source
New Antibiotics for Lower Respiratory Tract Infections
Microbiology ResearchRespiratory tract infections are frequently encountered in clinical practice. The growing incidence of antimicrobial resistance among the causative pathogens exerts sustained pressure on the existing therapeutic options.
Despoina Papageorgiou +5 more
doaj +1 more source
β-Lactam/β-Lactamase Inhibitor Combination Antibiotics Under Development
PathogensAntimicrobial resistance remains a public health problem of global concern with a great health and financial burden. Its recognition as a threat by political leadership has boosted the research and development of new antibiotics and particularly novel ...
Angeliki Katsarou +4 more
doaj +1 more source
Treatment Strategies of Colistin Resistance Acinetobacter baumannii Infections
AntibioticsAcinetobacter baumannii has emerged as a pressing challenge in clinical practice, mainly due to the development of resistance to multiple antibiotics, including colistin, one of the last-resort treatments.
Andria Papazachariou +5 more
doaj +1 more source
New antibiotics approved by EMA and FDA (2020–2024): Trends, access in Bulgaria, and implications for antimicrobial resistance control [PDF]
The aim of the study is to identify trends by analyzing the new antibacterial drugs approved by the EMA and FDA during the period 2020-2024, which can be used for planning antibiotic policies in healthcare institutions providing hospital care.
Ilieva, Mariya
core +2 more sources
npj Antimicrobials and ResistanceThe multiply antibiotic-resistant lineage 1 of Acinetobacter baumannii global clone 1 (GC1) emerged in the 1970s, and subsequently more extensively resistant sublineages have emerged.
Christopher J. Harmer +4 more
doaj +1 more source
Clinical Outcomes and Bacterial Characteristics of Carbapenem-resistant Acinetobacter baumannii Among Patients From Different Global Regions. [PDF]
BACKGROUND: Carbapenem-resistant Acinetobacter baumannii (CRAb) is 1 of the most problematic antimicrobial-resistant bacteria. We sought to elucidate the international epidemiology and clinical impact of CRAb.
Alenazi, Thamer +41 more
core +1 more source
What do We Know so Far about Ges Carbapenemases, and What Threat do They Pose?
Postępy MikrobiologiiCarbapenemases, classified as bacterial enzymes, have the ability to hydrolyze carbapenems – important broad-spectrum antibiotics. This work attempts to summarize the information on the diversity of Guiana Extended-Spectrum (GES) subgroup of ...
Rutkowski Kamil +6 more
doaj +1 more source