Results 81 to 90 of about 924 (199)

Influence of Aging and Immune Alterations on Susceptibility to Pneumococcal Pneumonia in the Elderly. [PDF]

Pneumonia is a common respiratory infection affecting individuals of all ages, with a significantly higher incidence among the elderly. As the aging population grows, pneumonia is expected to become an increasingly critical health concern.
Agrawal, Anshu, Kang, Nathan, Subramanian, Veedamali   +2 more
core   +1 more source

Microbiological eradication of XDR Acinetobacter baumannii intra-abdominal infection using sulbactam-durobactam: clinical and microbiological outcomes amidst irreversible host comorbidities

Frontiers in Medicine
BackgroundThe management of extensively drug-resistant (XDR) Acinetobacter baumannii (CRAB) in deep-seated infections remains a critical challenge, particularly when compounded by severe host comorbidities.Case presentationWe report the case of a 63-year-
Lei Yu, Jieli He, Waiming Chan, Waiming Chan, Shan Zou, Qingshan Zhou, Jun Jin   +6 more
doaj   +1 more source

Neumonía asociada a la ventilación mecánica. [PDF]

Introduction: Ventilator-associated pneumonia is a healthcare-associated infection that causes increased morbidity and mortality in the intensive care unit 48 hours after endotracheal intubation and invasive mechanical ventilation.
Canales Vélez , Stefanny Michell, Chalco Román , Graciela Jemima, Cárdenas Matute, Rebeca Tamara, Hidalgo Acosta, Javier Aquiles, Toala Zambrano, Gabriela Roxana   +4 more
core   +2 more sources

Innovative Antibiotic Therapies for Carbapenem-Resistant Gram-Negative Bacterial Infections: Clinical Efficacy, Safety, and Comparative Studies

Microorganisms
This review provides an overview of recent research and advancements in infection prevention and the treatment of drug-resistant bacterial diseases.
Majid Eslami, Amirabbas Safaripour, Seyedeh Zahra Banihashemian, Sahar Nikjoo Niaragh, Mohammad Amin Hemmati, Arefeh Shojaeian, Setayesh Fakhariyan, Atiye Rabbani, Valentyn Oksenych   +8 more
doaj   +1 more source

PNEUMONIA ADQUIRIDA NA COMUNIDADE: UM ESTUDO SOBRE TRATAMENTO EM REGIME DE INTERNAÇÃO [PDF]

A pneumonia adquirida na comunidade (PAC) é uma condição que requer atenção diferenciada, dado seu impacto significativo na saúde pública e nos sistemas de saúde.
Eudyslaine Kennia de Souza, Maria Caroline Moyses Bastos, Roberto Spadoni Campigotto, Yamila Audrey Santos Costa   +3 more
core   +2 more sources

Avanços na terapia antimicrobiana em infecções causadas pela espécie Acinetobacter baumannii [PDF]

, 2019
Acinetobacter baumannii is often associated to healthcare-associated infections, representing a serious public health problem, as it increases the risk of death in critically ill and immunocompromised patients.
Josiane Patrícia Nogueira da Cunha
core  

The changing landscape of antimicrobial resistance and use in South Africa: The need for access to new antibiotics: A position paper [PDF]

Antibiotic resistance is a global threat, with a disproportionate burden of mortality in low- and middle-income countries. It is increasing in both the public and private healthcare sectors within South Africa, especially in Gram-negative organisms, and ...
Chibabhai, V, Finlayson, H, Jeena, P, Kolman, S, Lowman, W, Manzini, T C, Nana, T, Nuttall, J, Parker, A, Skosana, P, Ueckermann, V, Wise, A   +11 more
core   +2 more sources

In vitro activity of cefiderocol against European Pseudomonas aeruginosa and Acinetobacter spp., including isolates resistant to meropenem and recent β-lactam/β-lactamase inhibitor combinations

Microbiology Spectrum
Carbapenem-resistant Pseudomonas aeruginosa and Acinetobacter spp. represent major threats and have few approved therapeutic options. Non-‍fermenting Gram-negative isolates were collected from hospitalized inpatients from 49 sites in 6 European countries
Anne Santerre Henriksen, Katy Jeannot, Antonio Oliver, John D. Perry, Mathias W. Pletz, Stefania Stefani, Ian Morrissey, Christopher Longshaw   +7 more
doaj   +1 more source

Activity of ampicillin-sulbactam, sulbactam-durlobactam, and comparators against Acinetobacter baumannii-calcoaceticus complex strains isolated from respiratory and bloodstream sources: results from ACNBio study [PDF]

Infections caused by carbapenem-resistant Acinetobacter baumannii-calcoaceticus complex (ABC) are associated with high mortality rates and limited treatment options.
Abbo, Lilian M., Acinetobacter baumannii Complex National Biorepository (ACNBio) Study Group, Argotsinger, Jill, Asempa, Tomefa E., Beck, Eric T., Buyukyanbolu, Ecem, Chamberland, Robin R., Clark, Andrew E., Daniels, Anne R., Dumm, Rebekah E., Fisher, Mark, Gialanella, Philip, Hamilton-Seth, Robert, Hand, Jonathan, Hankins, Julia D., Harrington, Amanda T., Humphries, Romney M., Huse, Holly, Kirn, Thomas J., Kufel, Wesley D., Liesman, Rachael, Marino, Jamie, Martinez, Octavio, Mochon, Brian, Narayanan, Navaneeth, Nicolau, David P., Pierce, Virginia M., Potula, Raghava, Riddell, Scott W., Simner, Patricia J., Tekle, Tsigereda, Tibbetts, Robert J., Vu, Christine, Westblade, Lars F.   +33 more
core   +1 more source

Sulbactam–durlobactam: a β-lactam/β-lactamase inhibitor combination targeting Acinetobacter baumannii

Future Microbiology
Sulbactam-durlobactam is a pathogen-targeted β-lactam/β-lactamase inhibitor combination that has been approved by the US FDA for the treatment of hospital-acquired and ventilator-associated bacterial pneumonia caused by susceptible isolates of Acinetobacter baumannii-calcoaceticus complex (ABC) in patients 18 years of age and older.
Sarah M McLeod, John P O'Donnell, Navaneeth Narayanan, John P Mills, Keith S Kaye   +4 more
openaire   +2 more sources