Results 141 to 150 of about 71,232 (305)
The Astrophysical JournalThe ability to determine galaxy properties such as masses, ages, and star formation rates robustly is critically limited by the ability to measure dust attenuation accurately.
Daniel Maschmann +4 more
doaj +1 more source
Advanced Science, EarlyView.A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie +7 more
wiley +1 more source
Advanced Science, EarlyView.Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen +16 more
wiley +1 more source
Hints of Disk Substructure in the First Brown Dwarf with a Dynamical Mass Constraint
The Astrophysical Journal LettersWe present high-resolution Atacama Large Millimeter/submillimeter Array (ALMA) observations at 0.89 mm of the Class II brown dwarf 2MASS J04442713+2512164 (2M0444), achieving a spatial resolution of 0 $\mathop{.}\limits^{^{\prime\prime} }$ 046 (∼6.4 au ...
Alejandro Santamaría-Miranda +16 more
doaj +1 more source
Mapping the interstellar medium in galaxies with Herschel/SPIRE [PDF]
, 2010 The standard method of mapping the interstellar medium in a galaxy, by observing the molecular gas in the CO 1-0 line and the atomic gas in the 21-cm line, is largely limited with current telescopes to galaxies in the nearby universe.
Bock, J. J. +4 more
core
Advanced Science, EarlyView.This study employs longitudinal fluorescence imaging in transgenic mice to map post‐craniotomy cortical recovery. We identify distinct neuroimmune recovery phases: microglial structural inflammation peaks at ∼10 days, neuronal structural intensity peaks at ∼14 days and correlates with microglial activity, and functional network modularity is most ...
Guihua Xiao +13 more
wiley +1 more source
Single‐Mitochondrion ATP Profiling Directs Discovery of Targetable OXPHOS Dependency in Cancers
Advanced Science, EarlyView.MitoATP‐nFCM integrates nano‐flow cytometry with fluorogenic probes (ATP/membrane potential) and antibodies to quantify mitochondrial metabolites and protein expression at single‐organelle resolution, exposing oxidative phosphorylation (OXPHOS)‐driven metabolic rewiring in cancers.
Xu Xiao +7 more
wiley +1 more source
ALMA High-resolution Observation for the Transitional Disk Around IRAS 04125+2902
The Astrophysical JournalRecently, the youngest transiting planet was discovered around the T Tauri star, IRAS 04125+2902, in the Taurus-Auriga star-forming region. This system is crucial for understanding the early stages of planet formation.
Ayumu Shoshi +7 more
doaj +1 more source
Probing the Protostellar Envelope around L1157: the Dust and Gas Connection
, 2009 We present observations of the Class 0 protostar L1157-mm using the Combined Array for Research in Millimeter-wave Astronomy (CARMA) in 3 mm dust continuum and N2H+ line emission.
Aikawa +62 more
core +1 more source
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
Advanced Science, EarlyView.NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source