Results 11 to 20 of about 3,339 (149)

Impact of short‐term Dutasteride treatment on prostate‐specific membrane antigen expression in a mouse xenograft model

Cancer Reports, 2021
Background Dutasteride has been shown to increase expression of the prostate‐specific membrane antigen (PSMA) in prostate cancer cells in previous in vitro studies. This 5‐alpha‐reductase inhibitor is commonly used for the treatment of symptomatic benign
Benedikt Kranzbühler, Rosa Sousa, Lukas Prause, Irene A. Burger, Niels J. Rupp, Tullio Sulser, Souzan Salemi, Daniel Eberli   +7 more
doaj   +1 more source

Transurethral Resection of Prostate and Blood loss: Efficacy of Dutasteride in reducing perioperative blood loss.

International Journal of Endorsing Health Science Research, 2021
Background: Benign Prostatic Hyperplasia (BPH) is the most common urological cause of urinary obstruction, affecting men above 50 years of age.
Shakeel Haseeb uddin Siddique, Salman El Khalid, Muhammad Shoaib Mithani, Abdul Wasay Mahmood, Shariq Anis Khan, Fakhir Yousuf   +5 more
doaj   +1 more source

Short course of dutasteride in treatment of a refractory category IIIB chronic prostatitis (A placebo-controlled study)

Prostate International, 2022
Objective: To evaluate the short-term efficacy of Dutasteride in the management of chronic prostatitis (CP)/chronic pelvic pain syndrome. Materials and methods: A randomized placebo-controlled double-blind study was conducted that including 50 patients ...
Ahmed Higazy, A.A. Shorbagy, Mohamed Shabayek, Ahmed Radwan, George N. Halim, Dana Osman, Tarek Osman   +6 more
doaj   +1 more source

Preventive and therapeutic efficacy of finasteride and dutasteride in TRAMP mice. [PDF]

PLoS ONE, 2013
BACKGROUND:The prostate cancer prevention trial (PCPT) and Reduction by dutasteride of Prostate Cancer Events (REDUCE) trial found that 5α-reductase (5αR) inhibitors finasteride and dutasteride respectively, decreased prostate cancer prevalence but also ...
Alexander B Opoku-Acheampong, Dave Unis, Jamie N Henningson, Amanda P Beck, Brian L Lindshield   +4 more
doaj   +1 more source

Does treatment with dutasteride or finasteride has impact on renal morphology? Experimental study

Acta Cirúrgica Brasileira, 2021
Purpose: To investigate whether renal modifications occur following treatment with dutasteride or finasteride. Methods: Twenty-four male rats were divided into three groups: control (that received distilled water), dutasteride (0.5 mg/kg/day), and ...
Marcello Henrique Araújo da Silva, João Henrique Duque Estrada, Bianca Martins Gregório, Francisco José Barcellos Sampaio, Diogo Benchimol de Souza   +4 more
doaj   +1 more source

Formulation of a film-coated dutasteride tablet bioequivalent to a soft gelatin capsule (Avodart®): Effect of γ-cyclodextrin and solubilizers

Asian Journal of Pharmaceutical Sciences, 2019
The aim of this study was to optimize a tablet formulation of dutasteride that is bioequivalent to a commercially available soft gelatin capsule (Avodart®).
Mi-Hong Min, Jin-Hyong Park, Mi-Ran Choi, Jong-Hyun Hur, Byung-Nak Ahn, Dae-Duk Kim   +5 more
doaj   +1 more source

The role of preoperative dutasteride in reducing bleeding during transurethral resection of the prostate: A systematic review and meta-analysis of randomized controlled trials

Asian Journal of Urology, 2022
Objective: Bleeding is one of the most common complications of transurethral resection of the prostate (TURP). Several previous studies reported that administering dutasteride before surgery could reduce perioperative bleeding.
Yudhistira Pradnyan Kloping, Niwanda Yogiswara, Yusuf Azmi   +2 more
doaj   +1 more source

The impact of finasteride and dutasteride treatments on proliferation, apoptosis, androgen receptor, 5α-reductase 1 and 5α-reductase 2 in TRAMP mouse prostates

Heliyon, 2017
Background: Previously, we studied the effect of finasteride- or dutasteride-containing diets in male C57BL/6 TRAMP x FVB mice. Pre (6 weeks of age) and post (12 weeks of age) groups received finasteride or dutasteride to determine the efficacy of these ...
Alexander B. Opoku-Acheampong, Jamie N. Henningson, Brian L. Lindshield   +2 more
doaj   +1 more source

Free combination of dutasteride plus tamsulosin for the treatment of benign prostatic hyperplasia in South Korea: analysis of drug utilization and adverse events using the National Health Insurance Review and Assessment Service database

BMC Urology, 2021
Objective To assess the use and safety of free combination therapy (dutasteride and tamsulosin), dutasteride monotherapy, or tamsulosin monotherapy in patients with benign prostatic hyperplasia (BPH).
Zrinka Lulic, Hwancheol Son, Sang-Bae Yoo, Marianne Cunnington, Pratiksha Kapse, Diane Miller, Vanessa Cortes, Suna Park, Rachel H. Bhak, Mei Sheng Duh   +9 more
doaj   +1 more source

Patterns of finasteride and dutasteride use in the prostate, lung, colorectal and ovarian (PLCO) cancer screening trial cohort: effects of socio-demographic factors and a black box warning [PDF]

Journal of Men's Health, 2022
Background: Five-alpha reductase inhibitors (5-ARIs), specifically finasteride and dutasteride, have been shown to significantly reduce prostate cancer incidence.
Jarrett A. Johnson, Paul F. Pinsky, Howard L. Parnes, Damali N. Martin   +3 more
doaj   +1 more source