Results 51 to 60 of about 3,490 (164)

Potential Anticancer, Anti-inflammatory, and Antioxidant Effects of Dutasteride on LNCap Prostate Cancer Cell Line

Medical Journal of Babylon
Background: Prostate cancer (PCa) is one of the main causes of death in men across the world. Particular focus has been placed on its preventative and treatment techniques, which include focusing on the activity of 5-alpha reductase enzyme which is ...
Zahraa Abdulhasan Jihad, Majid Kadhim Abbas, Kaiser N. Madlum   +2 more
doaj   +1 more source

The influence of age and the presence of prostate cancer on prostate volume, PSA and PSA density

BJU International, Volume 137, Issue 5, Page 805-812, May 2026.
Objective To assess prostate volume (PV) changes with age in symptomatic and asymptomatic men with and without clinically significant prostate cancer (csPCa). In symptomatic patients, we additionally analysed the effect of age and csPCa on PSA and PSA‐density (PSA‐D) and compared these to current National Institute for Health and Care Excellence (NICE)
Jill Rusbridge, Iztok Caglic, Liness Thavaraja, Nikita Sushentsev, Tristan Barrett   +4 more
wiley   +1 more source

Efficacy and safety of oral finasteride versus dutasteride in moderate-to-severe androgenetic alopecia in males based on trichoscopic and laboratory findings: a clinical comparison in Iran

Journal of Dermatological Treatment
Background Androgenetic alopecia (AGA) is the most common type of hair loss in men. Finasteride and dutasteride are oral 5-alpha-reductase inhibitors. This study compared their efficacy and safety in Iranian men with moderate to severe AGA.Methods This ...
Nazila Poostiyan, Zahra Nikyar, Reza Makhmali, Mohsen Hosseini, Zabihollah Shahmoradi   +4 more
doaj   +1 more source

Efficacy of tadalafil treatment on erectile dysfunction in patients under dutasteride treatment: A prospective non-randomized comparative study

Urology Research and Practice, 2019
Objective: In this study, we aimed to evaluate the efficacy of tadalafil in the management of erectile dysfunction in patients under dutasteride medication for bladder outlet obstruction.
Önder Yaman, Mete Özkıdık, Mehmet İlker Gökce   +2 more
doaj   +1 more source

Impact of Hormonal and Radiation Therapy on Bladder Outlet Obstruction in High‐Risk Localized Prostate Cancer: A Prospective Pressure‐Flow Study

International Journal of Urology, Volume 33, Issue 5, May 2026.
ABSTRACT Purpose There are few reports investigating urodynamic changes after radiotherapy and hormonal therapy (HT) for prostate cancer. We prospectively evaluated differences in bladder outlet obstruction (BOO) using pressure‐flow studies (PFS) before and after HT and radiotherapy in patients with high‐risk localized or locally advanced prostate ...
Yuki Kyoda, Masakazu Hori, Mitsuhiro Nakanishi, Tetsuya Shindo, Kohei Hashimoto, Ko Kobayashi, Toshiaki Tanaka, Naoya Masumori   +7 more
wiley   +1 more source

Process Factors Affecting the Preparation and Characterization of Dutasteride Nanosuspension

Iraqi Journal of Pharmaceutical Sciences
Dutasteride, a synthetic compound belonging to the 4-azasteroid class, functions as a selective and competitive inhibitor of both type 1 and type 2 5-alpha-reductase enzymes.
Shaimaa N. Abd-Alhammid , Rusul Wahhab Kadhum   +1 more
doaj   +1 more source

Metastatic Prostate Cancer Masquerading as Locally Advanced Breast Cancer

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT We report a rare case of a 72‐year‐old man with prostatic adenocarcinoma metastasizing to gynecomastia breast tissue with ipsilateral axillary lymph node involvement. This presentation is notable for the absence of disseminated metastatic disease or prolonged androgen deprivation therapy.
Tess Howard, Mylestone Gobe Monna, Jasmine Zhu, Jiasian Teh, Sze Ting Lee, Grace L Chew   +5 more
wiley   +1 more source

Comparison of Finasteride and Dutasteride on Risk of Prostate Cancer in Patients with Benign Prostatic Hyperplasia: A Pooled Analysis of 15 Real-world Databases

The World Journal of Men's Health
Purpose: Finasteride and dutasteride are used to treat benign prostatic hyperplasia (BPH) and reduce the risk of developing prostate cancer. Finasteride blocks only the type 2 form of 5-alpha-reductase, whereas dutasteride blocks both type 1 and 2 forms
Dae Yul Yang, Won-Woo Seo, Rae Woong Park, Sang Youl Rhee, Jae Myung Cha, Yoon Soo Hah, Chang Won Jeong, Kyung-Jin Kim, Hyeon-Jong Yang, Do Kyung Kim, Ji Yong Ha   +10 more
doaj   +1 more source

Adverse Sexual Effects of Treatment with Finasteride or Dutasteride for Male Androgenetic Alopecia: A Systematic Review and Meta-analysis

Acta Dermato-Venereologica, 2018
Treatment of male androgenetic alopecia with 5α-reductase inhibitors is efficacious. However, the risk of adverse sexual effects remains controversial.
Solam Lee, Young Bin Lee, Sung Jay Choe, Won-Soo Lee   +3 more
doaj   +1 more source

Evaluating the Effectiveness of Commercial Oral Supplements for Hair Growth: A Systematic Review and Meta‐Analysis

Journal of Cosmetic Dermatology, Volume 25, Issue 4, April 2026.
ABSTRACT Background Hair loss is a common condition affecting both men and women, with significant psychosocial impact. While oral supplements are marketed to improve hair growth, their clinical efficacy remains debated. This systematic review aimed to evaluate the effectiveness and safety of commercial oral nutraceuticals for hair growth.
Razan Alanazi, Shadan Alshammari, Kadi Aldossari, Raneem Alwatban, Deema Aljeribah, Shoog Alanazi, Abdulaziz Alsalhi, Aminah Alhumam, Abdulmajeed Alajlan   +8 more
wiley   +1 more source